Применение внутривенных иммуноглобулинов в детской гематологии-онкологии и трансплантации гемопоэтических стволовых клеток: свойства и показания – опыт федеральных центров

Кирилл Игоревич Киргизов,Татьяна Викторовна Шаманская,Екатерина Андреевна Пристанскова,Вероника Владиковна Константинова,Н.В. Сидорова,Д. Ю. Качанов,Светлана Рафаэлевна Варфоломеева,Е. В. Скоробогатова

Published 2015 in Unknown venue

ABSTRACT

This paper gives information on the structure of immunoglobulin molecules and the functions of each of them, as well as on the plasma levels of immunoglobulins. It provides basic requirements for the safety of intravenous immunoglobulins (IVVGs) and indications for their use in hematology/oncology and hematopoietic stem cell transplantation. Their doses, regimens, and possible adverse reactions are shown for a number of diseases. Moreover, the paper describes the experience with 10 % IVVGs in the federal center and gives brief clinical examples of the efficiency of using these agents.

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