Isolated hepatic perfusion: experimental evidence and clinical utility.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Surgical Clinics of North America

• Publication date

  2004-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0039-6109(03)00233-0PMID 15062665
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• High mitomycin C concentration in tumour tissue can be achieved by isolated liver perfusion in rats

  2004cited by this paper
• Percutaneous isolated hepatic perfusion for chemotherapy: a phase 1 study.

  2003cited by this paper
• Degree of tumour vascularity correlates with drug accumulation and tumour response upon TNF-α-based isolated hepatic perfusion

  2003cited by this paper
• Locoregional Therapies for Hepatocellular Carcinoma: A Critical Review From the Surgeon’s Perspective

  2002cited by this paper
• Reduced Liver Uptake of Arterially Infused Melphalan during Retrograde Rat Liver Perfusion with Unaffected Liver Tumor Uptake

  2002cited by this paper
• Surgical treatment of liver metastases.

  2002influential reference
• Prerequisites for effective adenovirus mediated gene therapy of colorectal liver metastases in the rat using an intracellular neutralizing antibody fragment to p21-Ras

  2002cited by this paper
• Hepatic artery chemoembolization.

  2002cited by this paper
• The role of oxaliplatin in the treatment of advanced metastatic colorectal cancer: prospects and future directions.

  2002cited by this paper
• Antitumor effects of isolated hypoxic hepatic perfusion (IHHP) with high-dose TNF against colonic liver metastases in a rat model.

  2002cited by this paper
• Isolated liver perfusion for non-resectable liver tumours: a review.

  2002cited by this paper
• Percutaneous alcohol ablation for liver metastasis.

  2002cited by this paper
• Hepatic-arterial chemotherapy.

  2001cited by this paper
• Role of tumor necrosis factor on toxicity and cytokine production after isolated hepatic perfusion.

  2001cited by this paper
• Isolated hepatic perfusion for unresectable hepatic metastases from colorectal cancer.

  2001cited by this paper
• TNF- α augments intratumoural concentrations of doxorubicin in TNF- α -based isolated limb perfusion in rat sarcoma models and enhances anti-tumour effects

  2000cited by this paper
• Current status of isolated hepatic perfusion with or without tumor necrosis factor for the treatment of unresectable cancers confined to liver.

  2000cited by this paper
• Tumor Necrosis Factor-&agr; Augments Tumor Effects in Isolated Hepatic Perfusion With Melphalan in a Rat Sarcoma Model

  2000cited by this paper
• Isolated Limb Perfusion for Local Gene Delivery: Efficient and Targeted Adenovirus-Mediated Gene Transfer Into Soft Tissue Sarcomas

  2000cited by this paper
• A phase I-II study of isolated hepatic perfusion using melphalan with or without tumor necrosis factor for patients with ocular melanoma metastatic to liver.

  2000cited by this paper
• Increased local cytostatic drug exposure by isolated hepatic perfusion: a phase I clinical and pharmacologic evaluation of treatment with high dose melphalan in patients with colorectal cancer confined to the liver

  2000cited by this paper
• Isolated hypoxic hepatic perfusion (IHHP) using balloon catheter techniques: from laboratory to the clinic towards a percutaneous procedure.

  2000cited by this paper
• Pharmacokinetics of isolated hepatic perfusion with high dose tumor necrosis factor in rat model.

  2000cited by this paper
• Isolated Hyperthermic Liver Perfusion with High Dose Tumor Necrosis Factor Alpha in Pigs: An Experimental Study in Preparation of Clinical Use

  2000cited by this paper
• Tumour necrosis factor alpha increases melphalan concentration in tumour tissue after isolated limb perfusion

  2000cited by this paper
• Technique and results of hyperthermic isolated hepatic perfusion with tumor necrosis factor and melphalan for the treatment of unresectable hepatic malignancies.

  2000cited by this paper
• Radiofrequency ablation of unresectable primary and metastatic hepatic malignancies: results in 123 patients.

  1999cited by this paper
• Prerequisites for effective isolated limb perfusion using tumour necrosis factor alpha and melphalan in rats

  1999cited by this paper
• Radiofrequency Ablation of Unresectable Primary and Metastatic Hepatic Malignancies: Results in 123 Patients

  1999cited by this paper
• Isolated hepatic perfusion with extracorporeal oxygenation using hyperthermia, tumour necrosis factor alpha and melphalan.

  1999cited by this paper
• Isolated hepatic perfusion for lapine liver metastases: impact of hyperthermia on permeability of tumor neovasculature.

  1999cited by this paper
• Acute-phase response patterns in isolated hepatic perfusion with tumour necrosis factor alpha (TNF-alpha) and melphalan in patients with colorectal liver metastases.

  1999cited by this paper
• Acute‐phase response patterns in isolated hepatic perfusion with tumour necrosis factor α (TNF‐α) and melphalan in patients with colorectal liver metastases

  1999cited by this paper
• First experience and technical aspects of isolated liver perfusion for extensive liver metastasis.

  1998cited by this paper
• Augmented capillary leak during isolated hepatic perfusion (IHP) occurs via tumor necrosis factor-independent mechanisms.

  1998cited by this paper
• Isolated hepatic perfusion with tumor necrosis factor alpha and melphalan: experimental studies in pigs and phase I data from humans.

  1998cited by this paper
• Efficacy of repeated percutaneous isolated liver chemoperfusion in local control of unresectable hepatocellular carcinoma.

  1998cited by this paper
• Isolated hypoxic hepatic perfusion with tumor necrosis factor-alpha, melphalan, and mitomycin C using balloon catheter techniques: a pharmacokinetic study in pigs.

  1998cited by this paper
• Isolated hepatic perfusion with tumor necrosis factor and melphalan for unresectable cancers confined to the liver.

  1998cited by this paper
• Isolated limb perfusion in the sarcoma-bearing rat: a novel preclinical gene delivery system.

  1997cited by this paper
• Isolated hepatic perfusion in the pig with TNF-alpha with and without melphalan.

  1997cited by this paper
• Isolated limb perfusion with tumor necrosis factor and melphalan for limb salvage in 186 patients with locally advanced soft tissue extremity sarcomas. The cumulative multicenter European experience.

  1996cited by this paper
• Isolated limb perfusion with high-dose tumor necrosis factor-alpha in combination with interferon-gamma and melphalan for nonresectable extremity soft tissue sarcomas: a multicenter trial.

  1996cited by this paper
• Isolated liver perfusion with mitomycin C in the treatment of colorectal cancer metastases confined to the liver.

  1996cited by this paper
• Use of tumor necrosis factor in isolated hepatic perfusion.

  1994cited by this paper
• Isolated hyperthermic liver perfusion with chemotherapy for liver malignancy.

  1994cited by this paper
• Treatment of Metastatic Cancer to the Liver

  1994cited by this paper
• Treatment of Irresectable Soft Tissue Sarcomas of the Limbs by Isolation Perfusion with High Dose TNFα in Combination with Interferon-γ and Melphalan

  1993cited by this paper
• Tumor necrosis factor : molecular and cellular biology and clinical relevance

  1993cited by this paper
• High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma.

  1992cited by this paper
• Pharmacological evaluation of experimental isolated liver perfusion and hepatic artery infusion with 5-fluorouracil.

  1991cited by this paper
• Effectiveness of isolated liver perfusion with mitomycin C in the treatment of liver tumours of rat colorectal cancer.

  1991cited by this paper
• Increasing the effective concentration of melphalan in experimental rat liver tumours: comparison of isolated liver perfusion and hepatic artery infusion.

  1991cited by this paper
• Local treatment of liver metastases with recombinant tumour necrosis factor (rTNF): a phase one study.

  1991cited by this paper
• A technique for isolated liver perfusion in the rat with survival and results of cytotoxic drug perfusion on liver tumor growth.

  1990cited by this paper
• What is the evidence that tumors are angiogenesis dependent?

  1990cited by this paper
• A comparative study of isolated liver perfusion versus hepatic artery infusion with mitomycin C in rats.

  1990cited by this paper
• Intralesional application of recombinant human tumor necrosis factor alpha induces local tumor regression in patients with advanced malignancies.

  1989cited by this paper
• Vascularization of small liver metastases

  1989cited by this paper
• In vivo isolated liver perfusion technique in a rat hepatic metastasis model: 5-fluorouracil concentrations in tumor tissue.

  1988cited by this paper
• Regional infusion for colorectal hepatic metastases. A randomized trial comparing the hepatic artery with the portal vein.

  1987cited by this paper
• Tumor and liver drug uptake following hepatic artery and portal vein infusion.

  1987cited by this paper
• A successful technique of in vivo isolated liver perfusion in pigs.

  1986cited by this paper
• Tumoricidal effects and patient survival after hyperthermic liver perfusion.

  1986cited by this paper
• Hepatic artery infusion for metastatic neoplastic disease.

  1985cited by this paper
• Isolation‐Perfusion of the Liver with 5‐Fluorouracil

  1985cited by this paper
• Hepatic artery infusion for metastatic neoplastic disease.

  1985cited by this paper
• [Isolated liver perfusion in advanced metastases of colorectal cancers].

  1984cited by this paper
• Bisfosfonáty v léčbě kostního postižení u myelomu

  1984cited by this paper
• Hyperthermic isolation‐perfusion in vivo of the canine liver

  1983cited by this paper
• Cancer : Principles and Practice of Oncology

  1982cited by this paper
• The clinical correlation of an autopsy study of recurrent colorectal cancer.

  1979cited by this paper
• Comparison of Histologic and Colposcopic Findings in DES-Exposed Females

  1978cited by this paper
• Tumor angiogenesis: therapeutic implications.

  1971cited by this paper
• Studies on the isolated perfused pig liver

  1971cited by this paper
• Development of a technic for isolated perfusion of the liver.

  1961cited by this paper

• Regional Therapies for Hepatic Melanoma Metastases

  2019cites this paper
• Isolated Hepatic Perfusion with Melphalan for Primary or Metastatic Unresectable Cancers of the Liver: Safety and Feasibility in A U.S. Academic Medical Center

  2017cites this paper
• Percutaneous Isolated Hepatic Perfusion for the Treatment of Unresectable Liver Malignancies

  2015cites this paper
• Preclinical Characterization of GLS4, an Inhibitor of Hepatitis B Virus Core Particle Assembly

  2013cites this paper
• Isolated hypoxic hepatic perfusion with melphalan in patients with irresectable ocular melanoma metastases.

  2009cites this paper
• A Phase I Study of Hyperthermic Isolated Hepatic Perfusion with Oxaliplatin in the Treatment of Unresectable Liver Metastases from Colorectal Cancer

  2009cites this paper
• Pharmacotherapy of chronic viral hepatitis and hepatocellular carcinoma

  2008cites this paper
• Isolated Hypoxic Hepatic Perfusion with Retrograde Outflow in Patients with Irresectable Liver Metastases; A New Simplified Technique in Isolated Hepatic Perfusion

  2008cites this paper
• Clinical Aspects of Hepatocellular Carcinoma

  2008cites this paper
• Isolated hepatic perfusion for the treatment of liver tumors: sunset or sunrise?

  2008cites this paper
• Synergistic Antitumor Effects of Histamine Plus Melphalan in Isolated Hepatic Perfusion for Liver Metastases

  2007cites this paper
• Correlation Between Melphalan Pharmacokinetics and Hepatic Toxicity Following Hyperthermic Isolated Liver Perfusion for Unresectable Metastatic Disease

  2007cites this paper
• Histamine’s vasoactive properties improving response rates in solid tumor treatment

  2006cites this paper
• Isolated Hypoxic Hepatic Perfusion With Orthograde or Retrograde Flow in Patients With Irresectable Liver Metastases Using Percutaneous Balloon Catheter Techniques: A Phase I and II Study

  2004cites this paper