Phytohemagglutinin rapidly lyses S49 T-lymphoma cells and the cytotoxicity is not mediated by generation of cAMP or increase in cytosolic calcium.

No abstract is available for this paper.

• Publication year

  1990

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  1990-08-16

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0006-291X(90)90496-APMID 2167667
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Drink and diet.

  1995cited by this paper
• Cyclic AMP concentrations modulate both calcium flux and hydrolysis of phosphatidylinositol phosphates in mouse T lymphocytes.

  1988cited by this paper
• Quantitation of lymphocyte intracellular free calcium signals using indo-1.

  1988cited by this paper
• Cholera toxin partially inhibits the T-cell response to phytohaemagglutinin through the ADP-ribosylation of a 45 kDa membrane protein.

  1988cited by this paper
• Phosphoinositide metabolism and the calcium response to concanavalin A in S49 T-lymphoma cells. A comparison with thymocytes.

  1988cited by this paper
• Antiproliferative response of human leukemic cells: lectin induced inhibition of DNA synthesis and cellular metabolism.

  1987cited by this paper
• Characterization of PHA and anti-T3 induced transduction mechanisms in a human T-cell leukaemia line.

  1987cited by this paper
• Induction of release of cytotoxin from murine bone marrow cells by an animal lectin.

  1987cited by this paper
• A G protein directly regulates mammalian cardiac calcium channels.

  1987cited by this paper
• Antiproliferative response of human leukemic cells. Modulation of cytosolic protein kinase C activity by phytohemagglutinin.

  1987cited by this paper
• Characterization of the role for calcium influx in mitogen‐induced triggering of human T cells. Identification of calcium‐dependent and calcium‐independent signals

  1986cited by this paper
• Release of cytotoxin by macrophages on treatment with human placenta lectin.

  1986cited by this paper
• Induction of a cytotoxin from murine macrophages by an animal lectin.

  1986cited by this paper
• Purinergic modulation of T-lymphocyte activation: differential susceptibility of distinct activation steps and correlation with intracellular 3',5'-cyclic adenosine monophosphate accumulation.

  1986cited by this paper
• Participation of polymorphonuclear leukocyte-derived factor in murine tumour cell killing.

  1985cited by this paper
• A new generation of Ca2+ indicators with greatly improved fluorescence properties.

  1985cited by this paper
• T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes

  1982cited by this paper
• Prostaglandin inhibition of T-cell proliferation is mediated at two levels.

  1981cited by this paper
• Entamoeba histolytica "toxin": fetuin neutralizable and lectin-like.

  1980cited by this paper
• Early activation events in lectin-stimulated human lymphocytes: evidence that wheat germ agglutinin and mitogenic lectins cause similar early changes in lymphocyte metabolism.

  1980cited by this paper
• Cytotoxic, cell agglutinating, and syncytium forming effect of purified lectins from Ricinus communis on cultured cells.

  1979cited by this paper
• Selection of a variant lymphoma cell deficient in adenylate cyclase.

  1975cited by this paper
• Independence of theta and TL surface antigens and killing by thymidine, cortisol, phytohemagglutinin, and cyclic AMP in a murine lymphoma.

  1973cited by this paper
• The biochemistry of plant lectins (phytohemagglutinins).

  1973cited by this paper
• Retention of lymphocyte characteristics by myelomas and theta + -lymphomas: sensitivity to cortisol and phytohemagglutinin.

  1973cited by this paper
• Cyclic adenosine 3',5'-monophosphate in human lymphocytes. Alterations after phytohemagglutinin stimulation.

  1971cited by this paper
• Mouse myelomas and lymphomas in culture.

  1970cited by this paper
• Different locations of carbohydrate-containing sites in the surface membrane of normal and transformed mammalian cells

  1970cited by this paper
• Interaction of the carbohydrate-binding protein concanavalin A with normal and transformed cells.

  1969cited by this paper
• TISSUE CULTURE STUDIES OF THE HUMAN LYMPHOCYTE.

  1964cited by this paper
• REACTIONS OF NORMAL AND TUMOR CELL SURFACES TO ENZYMES. I. WHEAT-GERM LIPASE AND ASSOCIATED MUCOPOLYSACCHARIDES.

  1963cited by this paper

• The Cytolytic Effect of a Glycoconjugate Extracted from Corms of Saffron Plant (Crocus sativus) on Human Cell Lines in Culture

  2000cites this paper