Dopamine-based reward circuitry responsivity, genetics, and overeating.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Current topics in behavioral neurosciences

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1007/7854_2010_89PMID 21243471
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Reward circuitry responsivity to food predicts future increases in body mass: Moderating effects of DRD2 and DRD4

  2010cited by this paper
• Deficits of mesolimbic dopamine neurotransmission in rat dietary obesity.

  2009cited by this paper
• Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat.

  2008cited by this paper
• Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors

  2008cited by this paper
• Dissociating the Role of the Orbitofrontal Cortex and the Striatum in the Computation of Goal Values and Prediction Errors

  2008cited by this paper
• High-Fat Diet Exposure Increases Dopamine D2 Receptor and Decreases Dopamine Transporter Receptor Binding Density in the Nucleus Accumbens and Caudate Putamen of Mice

  2008cited by this paper
• Relation of reward from food intake and anticipated food intake to obesity: a functional magnetic resonance imaging study.

  2008cited by this paper
• A DRD4/BDNF gene-gene interaction associated with maximum BMI in women with bulimia nervosa.

  2008cited by this paper
• Correlation between body mass index and striatal dopamine transporter availability in healthy volunteers - A SPECT study

  2008cited by this paper
• Underweight rats have enhanced dopamine release and blunted acetylcholine response in the nucleus accumbens while bingeing on sucrose.

  2008cited by this paper
• Relation Between Obesity and Blunted Striatal Response to Food Is Moderated by TaqIA A1 Allele

  2008cited by this paper
• Differential neural response to alcohol priming and alcohol taste cues is associated with DRD4 VNTR and OPRM1 genotypes.

  2008cited by this paper
• Immediate Reward Bias in Humans: Fronto-Parietal Networks and a Role for the Catechol-O-Methyltransferase 158Val/Val Genotype

  2007cited by this paper
• Food reinforcement and eating: a multilevel analysis.

  2007cited by this paper
• Linking nucleus accumbens dopamine and blood oxygenation

  2007cited by this paper
• In defense of "dependence".

  2007cited by this paper
• Is decreased prefrontal cortical sensitivity to monetary reward associated with impaired motivation and self-control in cocaine addiction?

  2007cited by this paper
• Body Mass, DRD4, Physical Activity, Sedentary Behavior, and Family Socioeconomic Status: The Add Health Study

  2007cited by this paper
• Impairment of acquisition of cocaine self-administration in rats maintained on a high-fat diet.

  2007cited by this paper
• DRD4 VNTR polymorphism is associated with transient fMRI-BOLD responses to smoking cues

  2007cited by this paper
• Hypoinsulinemia Regulates Amphetamine-Induced Reverse Transport of Dopamine

  2007cited by this paper
• Identification of brain neurons expressing the dopamine D4 receptor gene using BAC transgenic mice

  2006cited by this paper
• Effects of arousal‐ and feeding‐related neuropeptides on dopaminergic and GABAergic neurons in the ventral tegmental area of the rat

  2006cited by this paper
• Ghrelin modulates the activity and synaptic input organization of midbrain dopamine neurons while promoting appetite.

  2006cited by this paper
• Insulin-Mediated Phosphorylation of the Proline-Rich Akt Substrate PRAS40 Is Impaired in Insulin Target Tissues of High-Fat Diet–Fed Rats

  2006cited by this paper
• Dopamine D4 receptor polymorphism modulates cue-elicited heroin craving in Chinese

  2006cited by this paper
• Association of Eating Disorders with Catechol-O-Methyltransferase Gene Functional Polymorphism

  2006cited by this paper
• Leptin in energy balance and reward: two faces of the same coin?

  2006cited by this paper
• Direct Involvement of Orexinergic Systems in the Activation of the Mesolimbic Dopamine Pathway and Related Behaviors Induced by Morphine

  2006cited by this paper
• Gene variants of brain dopamine pathways and smoking-induced dopamine release in the ventral caudate/nucleus accumbens.

  2006cited by this paper
• Association between obesity and psychiatric disorders in the US adult population.

  2006cited by this paper
• The effect of dopamine D2, D5 receptor and transporter (SLC6A3) polymorphisms on the cue‐elicited heroin craving in Chinese

  2006cited by this paper
• Hypocretin/Orexin Selectively Increases Dopamine Efflux within the Prefrontal Cortex: Involvement of the Ventral Tegmental Area

  2006cited by this paper
• Genes, brain, and behavior: Bridging disciplines

  2006cited by this paper
• Neural substrates for the processing of cognitive and affective aspects of taste in the brain.

  2006cited by this paper
• Dopamine transporter and D2 receptor binding densities in mice prone or resistant to chronic high fat diet-induced obesity.

  2006cited by this paper
• Imaging gene-substance interactions: the effect of the DRD2 TaqIA polymorphism and the dopamine agonist bromocriptine on the brain activation during the anticipation of reward.

  2006cited by this paper
• Evaluation of a structural polymorphism in the ankyrin repeat and kinase domain containing 1 (ANKK1) gene and the activation of executive attention networks

  2006cited by this paper
• Akt Is Essential for Insulin Modulation of Amphetamine-Induced Human Dopamine Transporter Cell-Surface Redistribution

  2005cited by this paper
• Body Mass Index and Marijuana Use

  2005cited by this paper
• Cue-elicited craving for food: a fresh approach to the study of binge eating.

  2005cited by this paper
• Effects of dopamine D2 receptor (DRD2) and transporter (SLC6A3) polymorphisms on smoking cue-induced cigarette craving among African-American smokers

  2005cited by this paper
• Midbrain dopamine neurons encode a quantitative reward prediction error signal.

  2005cited by this paper
• Relationship between dopaminergic neurotransmission, alcoholism, and reward deficiency syndrome

  2005cited by this paper
• Relation between food reinforcement and dopamine genotypes and its effect on food intake in smokers.

  2004cited by this paper
• The Catechol-O-Methyltransferase Polymorphism: Relations to the Tonic–Phasic Dopamine Hypothesis and Neuropsychiatric Phenotypes

  2004cited by this paper
• Food restriction and leptin impact brain reward circuitry in lean and obese Zucker rats.

  2004cited by this paper
• Hyperdopaminergic mutant mice have higher "wanting" but not "liking" for sweet rewards.

  2004cited by this paper
• Childhood Inattention and Dysphoria and Adult Obesity Associated with the Dopamine D4 receptor Gene in Overeating Women with Seasonal Affective Disorder

  2004cited by this paper
• Effects of chronic ICV leptin infusion on motor-activating effects of D-amphetamine in food-restricted and ad libitum fed rats.

  2004cited by this paper
• Association of Seven Polymorphisms of the D2 Dopamine Receptor Gene with Brain Receptor-Binding Characteristics

  2004cited by this paper
• Dopamine Receptor 4 (DRD4) 7-Repeat Allele Predicts Methylphenidate Dose Response in Children with Attention Deficit Hyperactivity Disorder: A Pharmacogenetic Study

  2004cited by this paper
• Restricted daily consumption of a highly palatable food (chocolate Ensure®) alters striatal enkephalin gene expression

  2003cited by this paper
• Feeding-induced dopamine release in dorsal striatum correlates with meal pleasantness ratings in healthy human volunteers

  2003influential reference
• Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat.

  2003cited by this paper
• The Taq IA and Ser311 Cys polymorphisms in the dopamine D2 receptor gene and obesity.

  2003cited by this paper
• Afferent modulation of dopamine neuron firing differentially regulates tonic and phasic dopamine transmission

  2003cited by this paper
• Dopamine D2 receptors and transporters in type 1 and 2 alcoholics measured with human whole hemisphere autoradiography

  2003cited by this paper
• Catechol O-Methyltransferase (COMT) mRNA Expression in the Dorsolateral Prefrontal Cortex of Patients with Schizophrenia

  2003cited by this paper
• Dopamine D2 receptors and transporters in type 1 and 2 alcoholics

  2002cited by this paper
• Dopamine transporter genotype as a risk factor for obesity in African-American smokers.

  2002cited by this paper
• The DRD4 VNTR polymorphism moderates craving after alcohol consumption.

  2002cited by this paper
• Repeated sucrose access influences dopamine D2 receptor density in the striatum

  2002cited by this paper
• Defense of body weight depends on dietary composition and palatability in rats with diet-induced obesity.

  2002cited by this paper
• Expression of dopaminergic receptors in the hypothalamus of lean and obese Zucker rats and food intake.

  2002cited by this paper
• PI 3‐kinase regulation of dopamine uptake

  2002cited by this paper
• Role of dopamine in drug reinforcement and addiction in humans: results from imaging studies.

  2002cited by this paper
• Relationships between the TaqI polymorphism of the dopamine D2 receptor and blood pressure in hyperglycaemic and normoglycaemic Chinese subjects

  2001cited by this paper
• Overexpression of dopamine D2 receptors reduces alcohol self‐administration

  2001cited by this paper
• Leptin Attenuates Acute Food Deprivation-Induced Relapse to Heroin Seeking

  2001cited by this paper
• Brain dopamine and obesity.

  2001cited by this paper
• Modulation of brain reward circuitry by leptin.

  2000cited by this paper
• Variant alleles of the D2 dopamine receptor gene and obesity

  2000cited by this paper
• GOLFα Mediates Dopamine D1 Receptor Signaling

  2000cited by this paper
• Intra-Accumbens Amphetamine Increases the Conditioned Incentive Salience of Sucrose Reward: Enhancement of Reward “Wanting” without Enhanced “Liking” or Response Reinforcement

  2000cited by this paper
• Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior.

  1998cited by this paper
• Food Deprivation Decreases mRNA and Activity of the Rat Dopamine Transporter

  1998cited by this paper
• Rostromedial hypothalamic monoamine changes in response to intravenous infusions of insulin and glucose in freely feeding obese Zucker rats: a microdialysis study.

  1996cited by this paper
• Modulation of Intracellular Cyclic AMP Levels by Different Human Dopamine D4 Receptor Variants

  1995cited by this paper
• Electrochemical monitoring of extracellular dopamine in nucleus accumbens of rats lever-pressing for food.

  1994cited by this paper
• The dopamine D2 receptor (DRD2) as a major gene in obesity and height.

  1993cited by this paper
• Responses of monkey dopamine neurons to reward and conditioned stimuli during successive steps of learning a delayed response task

  1993cited by this paper
• Dopamine and preparatory behavior: II. A neurochemical analysis.

  1989cited by this paper
• Ultrastructural immunocytochemistry of gamma-aminobutyrate in the cerebral and cerebellar cortex of the rat.

  1985cited by this paper

• Overexpression of the short isoform of the dopamine D2 receptor causes diet‐induced obesity and hyperglycemia in mice

  2025cites this paper
• The Pathologic Roles and Therapeutic Implications of Ghrelin/GHSR System in Mental Disorders

  2024cites this paper
• Development of novel tools for dissection of central versus peripheral dopamine D2-like receptor signaling in dysglycemia

  2024cites this paper
• Bibliometric analysis of orexin: A promising neuropeptide

  2024influential citation
• Mechanism and treatments of antipsychotic-induced weight gain

  2023cites this paper
• Ultra-Processed Food, Reward System and Childhood Obesity

  2023cites this paper
• Multilocus Genetic Profile Reflecting Low Dopaminergic Signaling Is Directly Associated with Obesity and Cardiometabolic Disorders Due to Antipsychotic Treatment

  2023influential citation
• Chronic pain precedes disrupted eating behavior in low-back pain patients

  2022cites this paper
• Animal Models of Eating Disorders

  2021cites this paper
• P.0302 Polymorphisms in dopamine d2 receptor gene are associated with obesity in antipsychotic treatment patients: no relationship with eating habits changes

  2021cites this paper
• Crème de la Créature: Dietary Influences on Behavior in Animal Models

  2021cites this paper
• Brain on Food: The Neuroepigenetics of Nutrition.

  2021cites this paper
• Converging vulnerability factors for compulsive food and drug use.

  2021cites this paper
• Associations of the ANKK1 and DRD2 gene polymorphisms with overweight, obesity and hedonic hunger among women from the Northwest of Iran

  2020cites this paper
• DRD2/ANKK1 Taq1A but not COMT single nucleotide polymorphisms contribute to the link between temporal impulsivity and obesity in men

  2020cites this paper
• Intermittent Extended Access Rodent Models of Compulsive Eating

  2020cites this paper
• Yale University School of Medicine.

  2020cites this paper
• Love at first taste: Activation in reward-related brain regions during single-trial naturalistic appetitive conditioning in humans.

  2020cites this paper
• What Drives Us? Chasing Reward in a Dopaminergic Society

  2020cites this paper
• Understanding the role of incentive salience in sexual decision-making.

  2020cites this paper
• Noninvasive neuromodulation of the prefrontal cortex in young women with obesity: a randomized clinical trial

  2020cites this paper
• The orexinergic neural pathway from the lateral hypothalamus to the nucleus accumbens and its regulation of palatable food intake.

  2020cites this paper
• The dark side of compulsive eating and food addiction

  2019cites this paper
• P.201 Genetic variants associated with low dopaminergic activity relate to parameters included in the metabolic syndrome after treatment with antipsychotics

  2019cites this paper
• Appetite effects of prefrontal stimulation depend on COMT Val158Met polymorphism: A randomized clinical trial.

  2019cites this paper
• Dopamine gene methylation patterns are associated with obesity markers and carbohydrate intake

  2018cites this paper
• Hungry brains: A meta‐analytical review of brain activation imaging studies on food perception and appetite in obese individuals

  2018cites this paper
• Palatable Food Dampens the Long-Term Behavioral and Endocrine Effects of Juvenile Stressor Exposure but May Also Provoke Metabolic Syndrome in Rats

  2018cites this paper
• Taq1a polymorphism (rs1800497) is associated with obesity‐related outcomes and dietary intake in a multi‐ethnic sample of children

  2018influential citation
• Lower dopamine tone in the striatum is associated with higher body mass index.

  2018cites this paper
• A High-fat, High-sugar 'Western' Diet Alters Dorsal Striatal Glutamate, Opioid, and Dopamine Transmission in Mice.

  2018cites this paper
• Co-Administration of Cabergoline and Gliclazide Improve Glycemic Parameters and Lipid Profile in T2DM

  2017cites this paper
• Enhanced incentive motivation in obesity-prone rats is mediated by NAc core CP-AMPARs

  2017cites this paper
• Are Environmental Contaminants Responsiblefor ‘Globesity’?

  2017cites this paper
• Emotional Eating, Binge Eating and Animal Models of Binge-Type Eating Disorders

  2017cites this paper
• Effects of Bariatric Surgery on Energy Homeostasis.

  2017cites this paper
• Effect of vertical sleeve gastrectomy on alcohol consumption and preferences in dietary obese rats and mice: A plausible role for altered ghrelin signaling.

  2017cites this paper
• Eating Your Feelings? Testing a Model of Employees’ Work-Related Stressors, Sleep Quality, and Unhealthy Eating

  2017cites this paper
• Age-Related Changes in Gustatory, Homeostatic, Reward, and Memory Processing of Sweet Taste in the Metabolic Syndrome: An fMRI Study

  2017cites this paper
• Altered reward anticipation: Potential explanation for weight gain in schizophrenia?

  2017cites this paper
• Enhanced cocaine-induced locomotor sensitization and intrinsic excitability of NAc medium spiny neurons in adult but not in adolescent rats susceptible to diet-induced obesity

  2016cites this paper
• Striatal Reward Activity and Antipsychotic-Associated Weight Change in Patients With Schizophrenia Undergoing Initial Treatment.

  2016cites this paper
• Low Dopamine D2 Receptor Increases Vulnerability to Obesity Via Reduced Physical Activity, Not Increased Appetitive Motivation.

  2016cites this paper
• Effets de différents types de chirurgie bariatrique sur les concentrations circulantes de ghréline

  2016cites this paper
• Functional state of hypothalamic signaling systems in rats with type 2 diabetes mellitus treated with intranasal insulin

  2016cites this paper
• Induced impulsiveness? : eating behaviour and the modulation of behavioural sub-types of impulsivity

  2016cites this paper
• The role of prolactin in andrology: what is new?

  2015cites this paper
• A Shared Molecular and Genetic Basis for Food and Drug Addiction: Overcoming Hypodopaminergic Trait/State by Incorporating Dopamine Agonistic Therapy in Psychiatry.

  2015cites this paper
• IMAGING IN ENDOCRINOLOGY: The use of functional MRI to study the endocrinology of appetite.

  2015cites this paper
• When Chocolate Seeking Becomes Compulsion: Gene-Environment Interplay

  2015cites this paper
• [Eating disorders in psychiatric patients during treatment with second generation antipsychotics].

  2015cites this paper
• THE EFFECT OF INSULIN SENSITIVITY ON CORTICOLIMBIC RESPONSES TO METABOLIC AND VISUAL FOOD CUES

  2015cites this paper
• Integration of reward signalling and appetite regulating peptide systems in the control of food‐cue responses

  2015influential citation
• Argument for a non‐linear relationship between severity of human obesity and dopaminergic tone

  2015cites this paper
• A high multivitamin diet fed to Wistar rat dams during pregnancy increases maternal weight gain later in life and alters homeostatic, hedonic and peripheral regulatory systems of energy balance.

  2015cites this paper
• Superadditive opercular activation to food flavor is mediated by enhanced temporal and limbic coupling

  2015cites this paper
• Evidence for a compulsive‐like behavior in rats exposed to alternate access to highly preferred palatable food

  2014cites this paper
• A Randomized, Double-Blind, Placebo-Controlled Pilot Study of Naltrexone to Counteract Antipsychotic-Associated Weight Gain: Proof of Concept

  2014cites this paper
• A physiological perspective on the neuroscience of eating.

  2014cites this paper
• A High Multivitamin Diet Fed To Wistar Rat Dams During Pregnancy Increases Later Life Maternal Weight Gain and Alters Homeostatic, Hedonic and Peripheral Regulatory Systems of Energy Balance.

  2014cites this paper
• High Fat Diet Affects The Dopamine Reward System: Importance Of Sex And Critical Developmental Periods

  2014cites this paper
• Potential Role of Addiction Pharmacotherapy in Problematic Eating Behavior

  2014cites this paper
• Therapygenetics in mindfulness-based cognitive therapy: do genes have an impact on therapy-induced change in real-life positive affective experiences?

  2014cites this paper
• Dopamine and glucose, obesity, and reward deficiency syndrome

  2014cites this paper
• Hatching the behavioral addiction egg: Reward Deficiency Solution System (RDSS)™ as a function of dopaminergic neurogenetics and brain functional connectivity linking all addictions under a common rubric

  2014cites this paper
• Animal Models of Compulsive Eating Behavior

  2014cites this paper
• Prevalence and Correlates of Attention Deficit Hyperactivity Disorder in Adults From a French Community Sample

  2014cites this paper
• Measurement of food reinforcement in preschool children. Associations with food intake, BMI, and reward sensitivity.

  2014cites this paper
• Convergent dysregulation of frontal cortical cognitive and reward systems in eating disorders

  2013cites this paper
• Pharmacotherapies for Overeating and Obesity.

  2013cites this paper
• Reward-based hypertension control by a synthetic brain–dopamine interface

  2013cites this paper
• Dopamine Signaling in reward-related behaviors

  2013cites this paper
• Investigating the safety and efficacy of naltrexone for anti-psychotic induced weight gain in severe mental illness: study protocol of a double-blind, randomized, placebo-controlled trial

  2013cites this paper
• Engineering of synthetic gene circuits for the treatment of metabolic diseases

  2013cites this paper
• Neurobehavioural correlates of body mass index and eating behaviours in adults: a systematic review.

  2013cites this paper
• Brain imaging in the context of food perception and eating

  2013cites this paper
• Dopamine signaling in food addiction: role of dopamine D2 receptors

  2013cites this paper
• Alcohol Reward Is Increased after Roux-en-Y Gastric Bypass in Dietary Obese Rats with Differential Effects following Ghrelin Antagonism

  2012cites this paper
• Sucres, addiction et obésité

  2012cites this paper
• Predictors of neuropsychiatric side effects of dopamine-agonist therapy in patients with prolactinomas

  2012cites this paper
• Sugar, addiction and obesity

  2012cites this paper
• Functional brain imaging of appetite.

  2012cites this paper
• Genetic influences on the human mesolimbic dopamine reward system

  2011cites this paper
• Neurobiology driving hyperactivity in activity-based anorexia.

  2011cites this paper
• Nutritional Therapy in Practice for Learning, Behavioural and Mood Disorders

  2011cites this paper
• Comparative and Ontogenic Biochemistry Functional State of Hypothalamic Signaling Systems in Rats with Type 2 Diabetes Mellitus Treated with Intranasal Insulin

  year unknowncites this paper