Simvastatin Decreases Endothelial Progenitor Cell Apoptosis in the Kidney of Hypertensive Hypercholesterolemic Pigs

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Arteriosclerosis, Thrombosis and Vascular Biology

• Publication date

  2010-05-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1161/ATVBAHA.109.201475PMID 20203299PMCID PMC2866120
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Endothelial Progenitor Cells Restore Renal Function in Chronic Experimental Renovascular Disease

  2009cited by this paper
• Effect of Oxidized Low-density Lipoprotein on Survival and Function of Endothelial Progenitor Cell Mediated by p38 Signal Pathway

  2009cited by this paper
• Angiomodulin Is a Specific Marker of Vasculature and Regulates Vascular Endothelial Growth Factor-A–Dependent Neoangiogenesis

  2009cited by this paper
• CHOP Mediates Endoplasmic Reticulum Stress-Induced Apoptosis in Gimap5-Deficient T Cells

  2009cited by this paper
• Apoptosis induced by endoplasmic reticulum stress involved in diabetic kidney disease.

  2008cited by this paper
• Oxidized low density lipoprotein impairs endothelial progenitor cell function by downregulation of E-selectin and integrin alpha(v)beta5.

  2008cited by this paper
• Atorvastatin treatment improves survival and effects of implanted mesenchymal stem cells in post-infarct swine hearts.

  2008cited by this paper
• HMG-CoA reductase inhibitors activate the unfolded protein response and induce cytoprotective GRP78 expression.

  2008cited by this paper
• Inhibition of Cardiac Remodeling by Pravastatin Is Associated with Amelioration of Endoplasmic Reticulum Stress

  2008cited by this paper
• Statin and Stromal Cell‐Derived Factor‐1 Additively Promote Angiogenesis by Enhancement of Progenitor Cells Incorporation into New Vessels

  2008cited by this paper
• Circulating endothelial cells and circulating endothelial progenitors in kidney disease--victims, witnesses, or accomplices?

  2008cited by this paper
• Simvastatin prevents coronary microvascular remodeling in renovascular hypertensive pigs.

  2007cited by this paper
• Uric acid heralds ischemic tissue injury to mobilize endothelial progenitor cells.

  2007cited by this paper
• Enhanced mobilization of bone marrow cells does not ameliorate renal fibrosis.

  2007cited by this paper
• Met-RANTES reduces endothelial progenitor cell homing to activated (glomerular) endothelium in vitro and in vivo.

  2007cited by this paper
• Rosuvastatin treatment prevents progressive kidney inflammation and fibrosis in stroke-prone rats.

  2007cited by this paper
• Antioxidant vitamins induce angiogenesis in the normal pig kidney.

  2007cited by this paper
• Angiotensin II-induced reactive oxygen species and the kidney.

  2007cited by this paper
• Oxidative stress on progenitor and stem cells in cardiovascular diseases.

  2006cited by this paper
• Effect of aggressive risk factor modification on cardiac events and myocardial ischaemia in patients with chronic kidney disease

  2006cited by this paper
• Renal manifestations in the metabolic syndrome.

  2006cited by this paper
• The effects of HMG-CoA reductase inhibitor on vascular progenitor cells.

  2006cited by this paper
• Role of Oxidative Stress in Remodeling of the Myocardial Microcirculation in Hypertension

  2006cited by this paper
• Cross-talk between the kidney and the cardiovascular system.

  2006cited by this paper
• Isolation and characterization of multipotent progenitor cells from the Bowman's capsule of adult human kidneys.

  2006cited by this paper
• L-Arginine Does Not Affect Renal Morphology and Cell Survival in Ischemic Acute Renal Failure in Rats

  2005cited by this paper
• Pathways of Renal Fibrosis and Modulation of Matrix Turnover in Experimental Hypercholesterolemia

  2005cited by this paper
• Risk factors for coronary artery disease, circulating endothelial progenitor cells, and the role of HMG-CoA reductase inhibitors.

  2005cited by this paper
• A biologic role of HIF-1 in the renal medulla.

  2005cited by this paper
• Comparison of acute and chronic antioxidant interventions in experimental renovascular disease.

  2004cited by this paper
• Antioxidant Intervention Attenuates Myocardial Neovascularization in Hypercholesterolemia

  2004cited by this paper
• Antioxidant intervention blunts renal injury in experimental renovascular disease.

  2004cited by this paper
• Decreased Number and Impaired Angiogenic Function of Endothelial Progenitor Cells in Patients With Chronic Renal Failure

  2004cited by this paper
• Atorvastatin improves the course of ischemic acute renal failure in aging rats.

  2004cited by this paper
• Stromal Cell–Derived Factor-1 Effects on Ex Vivo Expanded Endothelial Progenitor Cell Recruitment for Ischemic Neovascularization

  2003cited by this paper
• The role of arterial hypertension in the progression of non-diabetic glomerular diseases.

  2003cited by this paper
• Mechanisms of Renal Structural Alterations in Combined Hypercholesterolemia and Renal Artery Stenosis

  2003cited by this paper
• Lipid-lowering-independent effects of simvastatin on the kidney in experimental hypercholesterolaemia.

  2003cited by this paper
• Renal dysfunction complicating the treatment of hypertension.

  2002cited by this paper
• Distinct Renal Injury in Early Atherosclerosis and Renovascular Disease

  2002cited by this paper
• Increased Oxidative Stress in Experimental Renovascular Hypertension

  2001cited by this paper
• Simvastatin Preserves Coronary Endothelial Function in Hypercholesterolemia in the Absence of Lipid Lowering

  2001cited by this paper
• Combination of Hypercholesterolemia and Hypertension Augments Renal Function Abnormalities

  2001cited by this paper
• Noninvasive measurement of concurrent single-kidney perfusion, glomerular filtration, and tubular function.

  2001cited by this paper
• Expression of LOX-1, an oxidized low-density lipoprotein receptor, in experimental hypertensive glomerulosclerosis.

  2000cited by this paper
• Cerivastatin prevents angiotensin II-induced renal injury independent of blood pressure- and cholesterol-lowering effects.

  2000cited by this paper
• In vivo renal vascular and tubular function in experimental hypercholesterolemia.

  1999cited by this paper
• Monocyte infiltration and adhesion molecules in a rat model of high human renin hypertension.

  1999cited by this paper
• Cumulative effects of high cholesterol levels, high blood pressure, and cigarette smoking on carotid stenosis.

  1997cited by this paper
• Arterial hypertension and hyperlipidemia as determinants of glomerulosclerosis

  1993cited by this paper
• Interactions of hypercholesterolemia and hypertension in initiation of glomerular injury.

  1992cited by this paper
• A population at risk: Prevalence of high cholesterol levels in hypertensive patients in the framingham study

  1986cited by this paper
• Prevalence and prognostic significance of hypercholesterolemia in men with hypertension. Prospective data on the primary screenees of the Multiple Risk Factor Intervention Trial.

  1986cited by this paper
• The FASEB Journal • FJ Express Full-Length Article Simvastatin promotes angiogenesis and prevents microvascular remodeling in chronic renal ischemia

  year unknowncited by this paper

• Endothelial Progenitor Cells: Disease Markers and Potential Therapy in Kidney Disease.

  2025cites this paper
• The impact of hypoxia preconditioning on mesenchymal stem cells performance in hypertensive kidney disease

  2024cites this paper
• Potentials of Natural Antioxidants in Reducing Inflammation and Oxidative Stress in Chronic Kidney Disease

  2024cites this paper
• Kidney Intrinsic Mechanisms as Novel Targets in Renovascular Hypertension.

  2023cites this paper
• Effect of Hypoxia Preconditioning on the Regenerative Capacity of Adipose Tissue Derived Mesenchymal Stem Cells in a Model of Renal Artery Stenosis.

  2022cites this paper
• Emergent players in renovascular disease.

  2022cites this paper
• Natural products in the treatment of pulmonary emphysema: Therapeutic effects and mechanisms of action.

  2022cites this paper
• Diabetic Kidney Disease Alters the Transcriptome and Function of Human Adipose-Derived Mesenchymal Stromal Cells but Maintains Immunomodulatory and Paracrine Activities Important for Renal Repair

  2021cites this paper
• Chitosan Coated Microparticles Enhance Simvastatin Colon Targeting and Pro-Apoptotic Activity

  2020cites this paper
• Novel therapeutic strategies for renovascular disease.

  2019cites this paper
• Emerging Paradigms in Chronic Kidney Ischemia.

  2018cites this paper
• Effect of Simvastatin on Lipid Accumulation and the Expression of CXCL16 and Nephrin in Podocyte Induced by Oxidized LDL

  2018cites this paper
• Monascus Adlay and Monacolin K Attenuates Arterial Thrombosis in Rats through the Inhibition of ICAM-1 and Oxidative Stress

  2016cites this paper
• Role of the Renal Microcirculation in Progression of Chronic Kidney Injury in Obesity

  2016cites this paper
• Hypercholesterolemia Impairs Nonstenotic Kidney Outcomes After Reversal of Experimental Renovascular Hypertension.

  2016cites this paper
• Use of Statins to Augment Progenitor Cell Function in Preclinical and Clinical Studies of Regenerative Therapy: a Systematic Review

  2016cites this paper
• Gained in Translation: Protective Paradigms for the Poststenotic Kidney

  2015cites this paper
• Obesity and renovascular disease.

  2015cites this paper
• Mitochondria: A Pathogenic Paradigm in Hypertensive Renal Disease

  2015cites this paper
• Chronic renal ischemia in humans: can cell therapy repair the kidney in occlusive renovascular disease?

  2015cites this paper
• Paradigm Shifts in Atherosclerotic Renovascular Disease: Where Are We Now?

  2015cites this paper
• Ex vivo exposure of bone marrow from chronic kidney disease donor rats to pravastatin limits renal damage in recipient rats with chronic kidney disease

  2015cites this paper
• Sildenafil ameliorates oxidative stress and DNA damage in the stenotic kidneys in mice with renovascular hypertension

  2014cites this paper
• Endothelial dysfunction in conduit arteries and in microcirculation. Novel therapeutic approaches.

  2014influential citation
• Preserved Function of Late-Outgrowth Endothelial Cells in Medically Treated Hypertensive Patients Under Well-Controlled Conditions

  2014cites this paper
• UNIVERSIDADE FEDERAL DO ESPÍRITO SANTO CENTRO DE CIÊNCIAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS FISIOLÓGICAS

  2014cites this paper
• Effects of the herbal medicine composition "Saiko-ka-ryukotsu-borei-To" on the function of endothelial progenitor cells in hypertensive rats.

  2013cites this paper
• Renovascular Hypertension Leads to DNA Damage and Apoptosis in Bone Marrow Cells

  2013cites this paper
• Apolipoprotein A-I mimetic peptide reverse D-4F improves the biological functions of mouse bone marrow-derived late EPCs via PI3K/AKT/eNOS pathway

  2013cites this paper
• Therapeutic Potential of Traditional Chinese Medicine on Inflammatory Diseases

  2013cites this paper
• Dietary Monascus adlay supplements facilitate suppression of cigarette smoke-induced pulmonary endoplasmic reticulum stress, autophagy, apoptosis and emphysema-related PLGF in the rat.

  2013cites this paper
• Decreased endothelial progenitor cells and increased serum glycated albumin are independently correlated with plaque-forming carotid artery atherosclerosis in type 2 diabetes patients without documented ischemic disease.

  2012cites this paper
• Oxidized low density lipoprotein, stem cells, and atherosclerosis

  2012cites this paper
• Deciphering the Pathways of Death of Histoplasma capsulatum-Infected Macrophages: Implications for the Immunopathogenesis of Early Infection

  2012cites this paper
• Stem cell recruitment after injury: lessons for regenerative medicine.

  2012cites this paper
• Lipid lowering agents and the endothelium: an update after 4 years.

  2012cites this paper
• Adipose Tissue‐Derived Mesenchymal Stem Cells Improve Revascularization Outcomes to Restore Renal Function in Swine Atherosclerotic Renal Artery Stenosis

  2012cites this paper
• Noninvasive In Vivo Assessment of Renal Tissue Elasticity During Graded Renal Ischemia Using MR Elastography

  2011cites this paper
• Persistent kidney dysfunction in swine renal artery stenosis correlates with outer cortical microvascular remodeling.

  2011cites this paper
• The management of renovascular disease: ASTRAL and beyond

  2011cites this paper
• Statins and renovascular disease in the elderly: a population-based cohort study.

  2011cites this paper
• This information is current as Immunopathogenesis of Early Infection Macrophages : Implications for the-Infected Histoplasma capsulatum Deciphering the Pathways of Death of

  2011cites this paper
• Increased glomerular filtration rate in early metabolic syndrome is associated with renal adiposity and microvascular proliferation.

  2011cites this paper
• Statins--beyond lipids in CKD.

  2011cites this paper
• Statins—beyond lipids in CKD

  2011cites this paper
• Stem cells in cardiovascular regeneration: from preservation of endogenous repair to future cardiovascular therapies.

  2011cites this paper
• Textor Novel Interventions in Renovascular Disease 3 Activation of the Renin – Angiotensin – Aldosterone System

  year unknowncites this paper