The emerging role of poly(ADP-ribose) polymerase-1 in longevity.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  International Journal of Biochemistry and Cell Biology

• Publication date

  2005-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.BIOCEL.2004.10.006PMID 15743677
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Poly(ADP-Ribosyl)ation

  2006cited by this paper
• Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.

  2004cited by this paper
• PARP-1, PARP-2 and ATM in the DNA damage response: functional synergy in mouse development.

  2004cited by this paper
• The role of endogenous and exogenous DNA damage and mutagenesis.

  2004cited by this paper
• Resolution of Sister Telomere Association Is Required for Progression Through Mitosis

  2004cited by this paper
• The PARP superfamily

  2004cited by this paper
• The Human Rap1 Protein Complex and Modulation of Telomere Length*

  2004cited by this paper
• Functional Interaction between Poly(ADP-Ribose) Polymerase 2 (PARP-2) and TRF2: PARP Activity Negatively Regulates TRF2

  2004cited by this paper
• Werner syndrome protein--unwinding function to explain disease.

  2004cited by this paper
• Poly(ADP-ribose) polymerase (PARP-1) and p53 independently function in regulating double-strand break repair in primate cells.

  2004cited by this paper
• Phosphorylation regulates the interaction and complex formation between wt p53 protein and PARP‐1

  2003cited by this paper
• Poly(ADP-ribosyl)ation accelerates DNA repair in a pathway dependent on Cockayne syndrome B protein.

  2003cited by this paper
• Poly(ADP-ribose) polymerase-1 is a survival factor for radiation-exposed intestinal epithelial stem cells in vivo.

  2003cited by this paper
• PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression

  2003cited by this paper
• Genetic cooperation between the Werner syndrome protein and poly(ADP-ribose) polymerase-1 in preventing chromatid breaks, complex chromosomal rearrangements, and cancer in mice.

  2003cited by this paper
• Role of PARP Under Stress Conditions: Cell Death or Protection?

  2003cited by this paper
• Functional interaction between PARP‐1 and PARP‐2 in chromosome stability and embryonic development in mouse

  2003cited by this paper
• Physical and functional interaction of the Werner syndrome protein with poly‐ADP ribosyl transferase

  2003cited by this paper
• Mammalian longevity under the protection of PARP-1's multi-facets.

  2003cited by this paper
• Chromatin Loosening by Poly(ADP)-Ribose Polymerase (PARP) at Drosophila Puff Loci

  2003cited by this paper
• Animal Cytogenetics and Comparative Mapping

  2003cited by this paper
• Involvement of Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribosyl)ation in Regulation of Centrosome Function

  2003cited by this paper
• A requirement for PARP-1 for the assembly or stability of XRCC1 nuclear foci at sites of oxidative DNA damage.

  2003cited by this paper
• l-Selegiline Potentiates the Cellular Poly(ADP-Ribosyl)ation Response to Ionizing Radiation

  2003cited by this paper
• Central Role for the Werner Syndrome Protein/Poly(ADP-Ribose) Polymerase 1 Complex in the Poly(ADP-Ribosyl)ation Pathway after DNA Damage

  2003cited by this paper
• The biology of aging.

  2003cited by this paper
• The Drosophila heterochromatic gene encoding poly(ADP-ribose) polymerase (PARP) is required to modulate chromatin structure during development.

  2002cited by this paper
• Poly(ADP-ribose) polymerase-1 dependence of stress-induced transcription factors and associated gene expression in glia

  2002cited by this paper
• Oxidative stress shortens telomeres.

  2002cited by this paper
• Role for the Related Poly(ADP-Ribose) Polymerases Tankyrase 1 and 2 at Human Telomeres

  2002cited by this paper
• Mediation of Poly(ADP-Ribose) Polymerase-1-Dependent Cell Death by Apoptosis-Inducing Factor

  2002cited by this paper
• The Therapeutic Potential of Poly(ADP-Ribose) Polymerase Inhibitors

  2002cited by this paper
• PARP-1 modifies the effectiveness of p53-mediated DNA damage response

  2002cited by this paper
• Mechanisms of ageing

  2001cited by this paper
• PARP‐1: A Regulator of Genomic Stability Linked with Mammalian Longevity

  2001cited by this paper
• Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability.

  2001cited by this paper
• Ionising radiation induces the expression of PARP-1 and PARP-2 genes in Arabidopsis

  2001cited by this paper
• TANK2, a New TRF1-associated Poly(ADP-ribose) Polymerase, Causes Rapid Induction of Cell Death upon Overexpression*

  2001cited by this paper
• Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism.

  2001cited by this paper
• Regulation of p53 Sequence-specific DNA-binding by Covalent Poly(ADP-ribosyl)ation*

  2001cited by this paper
• Genomic instability in a PARP-1(-/-) cell line expressing PARP-1 DNA-binding domain.

  2001cited by this paper
• Comparative characterisation of poly(ADP-ribose) polymerase-1 from two mammalian species with different life span.

  2000cited by this paper
• Misregulation of gene expression in primary fibroblasts lacking poly(ADP-ribose) polymerase.

  2000cited by this paper
• New polymorphisms in the human poly(ADP-ribose) polymerase-1 coding sequence: lack of association with longevity or with increased cellular poly(ADP-ribosyl)ation capacity

  2000cited by this paper
• Negative regulation of alkylation‐induced sister‐chromatid exchange by poly(ADP‐ribose) polymerase‐1 activity

  2000cited by this paper
• Poly(ADP-ribose) Binds to Specific Domains in DNA Damage Checkpoint Proteins*

  2000cited by this paper
• Tankyrase Is a Golgi-associated Mitogen-activated Protein Kinase Substrate That Interacts with IRAP in GLUT4 Vesicles*

  2000cited by this paper
• Mammalian telomeres end in a large duplex loop.

  1999cited by this paper
• Trans-dominant inhibition of poly(ADP-ribosyl)ation potentiates alkylation-induced shuttle-vector mutagenesis in Chinese hamster cells

  1999cited by this paper
• The 193-Kd Vault Protein, Vparp, Is a Novel Poly(Adp-Ribose) Polymerase

  1999cited by this paper
• Resistance to endotoxic shock as a consequence of defective NF‐κB activation in poly (ADP‐ribose) polymerase‐1 deficient mice

  1999cited by this paper
• A Role of Poly (ADP-Ribose) Polymerase in NF- B Transcriptional Activation

  1999cited by this paper
• A role of poly (ADP-ribose) polymerase in NF-kappaB transcriptional activation.

  1999cited by this paper
• PARP-2, A Novel Mammalian DNA Damage-dependent Poly(ADP-ribose) Polymerase*

  1999cited by this paper
• Telomeres do D-loop-T-loop.

  1999cited by this paper
• Poly(ADP-ribose) Polymerase Null Mouse Cells Synthesize ADP-ribose Polymers*

  1998cited by this paper
• Tankyrase, a poly(ADP-ribose) polymerase at human telomeres.

  1998cited by this paper
• XRCC1 Is Specifically Associated with Poly(ADP-Ribose) Polymerase and Negatively Regulates Its Activity following DNA Damage

  1998cited by this paper
• Poly(ADP-ribose) Binds to Specific Domains of p53 and Alters Its DNA Binding Functions*

  1998cited by this paper
• Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication.

  1998cited by this paper
• Increased poly(ADP-ribose) polymerase activity in lymphoblastoid cell lines from centenarians

  1998cited by this paper
• Regulation of the expression or recruitment of components of the DNA synthesome by poly(ADP-ribose) polymerase.

  1998cited by this paper
• Oxidative Damage and Mutation to Mitochondrial DNA and Age‐dependent Decline of Mitochondrial Respiratory Function a

  1998cited by this paper
• Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells.

  1997cited by this paper
• Trans-dominant inhibition of poly(ADP-ribosyl)ation potentiates carcinogen induced gene amplification in SV40-transformed Chinese hamster cells.

  1996cited by this paper
• Positional Cloning of the Werner's Syndrome Gene

  1996cited by this paper
• trans-dominant inhibition of poly(ADP-ribosyl)ation sensitizes cells against gamma-irradiation and N-methyl-N'-nitro-N-nitrosoguanidine but does not limit DNA replication of a polyomavirus replicon

  1995cited by this paper
• Histone shuttling by poly ADP-ribosylation

  1992cited by this paper
• Poly(ADP-ribose) polymerase activity in mononuclear leukocytes of 13 mammalian species correlates with species-specific life span.

  1992cited by this paper
• Evolution of senescence: late survival sacrificed for reproduction.

  1991cited by this paper
• Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.

  1985cited by this paper
• Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure.

  1982cited by this paper
• Studies on the polymer of adenosine diphosphate ribose. I. Enzymic formation from nicotinamide adenine dinuclotide in mammalian nuclei.

  1967cited by this paper
• Polymerization of the adenosine 5'-diphosphate ribose moiety of NAD by rat liver nuclear enzyme.

  1967cited by this paper
• Nicotinamide mononucleotide activation of new DNA-dependent polyadenylic acid synthesizing nuclear enzyme.

  1963cited by this paper

• The PARP inhibitor olaparib promotes senescence in murine macrophages.

  2025cites this paper
• Kisspeptin Retards Tumor Growth of Lewis Lung Carcinoma Cells Through p38 MAPK-mediated Senescence

  2024cites this paper
• Evaluation of the efficacy of marine natural products against PARP-1/2 proteins in high-grade serous ovarian cancer: insights into MD and SMD simulations

  2024cites this paper
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  2024cites this paper
• Impact of Mitochondrial Architecture, Function, Redox Homeostasis, and Quality Control on Organismic Aging: Lessons from a Fungal Model System

  2023cites this paper
• Identification of indole-based natural compounds as inhibitors of PARP-1 against triple-negative breast cancer: a computational study

  2023cites this paper
• Telomere shortening and cellular senescence induced by oxalate and nephrolithiasis urine in HK-2 cells

  2023cites this paper
• Targeting the DNA damage response in pediatric malignancies

  2022cites this paper
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  2022cites this paper
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  2020cites this paper
• PYP1-4 peptide from Pyropia yezoensis protects against acetaminophen-induced hepatotoxicity in HepG2 cells

  2019cites this paper
• Radiation: a poly-traumatic hit leading to multi-organ injury

  2019cites this paper
• Targeting ADP-ribosylation as an antimicrobial strategy

  2019cites this paper
• Genome-Wide Profiling of PARP 1 Reveals an Interplay with Gene Regulatory Regions and DNA Methylation

  2019cites this paper
• Opportunities for the repurposing of PARP inhibitors for the therapy of non‐oncological diseases

  2018cites this paper
• Chelidonine inhibits TNF‐α‐induced inflammation by suppressing the NF‐κB pathways in HCT116 cells

  2018cites this paper
• Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases.

  2018cites this paper
• Antioxidant Vitamins and Ageing.

  2018cites this paper
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  2018cites this paper
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  2018cites this paper
• The Extract of Leonurus sibiricus Transgenic Roots with AtPAP1 Transcriptional Factor Induces Apoptosis via DNA Damage and Down Regulation of Selected Epigenetic Factors in Human Cancer Cells

  2018cites this paper
• Sirt1 and Parp1 as epigenome safeguards and microRNAs as SASP-associated signals, in cellular senescence and aging.

  2017cites this paper
• Improvement of non-alcoholic steatohepatitis by hepatocyte-like cells generated from iPSCs with Oct4/Sox2/Klf4/Parp1

  2017cites this paper
• Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span

  2017cites this paper
• Erratum: Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span

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• The Role of DNA Repair in the Evolution of Vertebrate Longevity

  2016cites this paper
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• Dihydromyricetin suppresses TNF-α-induced NF-κB activation and target gene expression

  2016cites this paper
• Radiosensitization by PARP Inhibition in DNA Repair Proficient and Deficient Tumor Cells: Proliferative Recovery in Senescent Cells

  2016cites this paper
• Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study

  2016cites this paper
• Poly(ADP-ribose) polymerase inhibition suppresses inflammation and promotes recovery from adrenal injury in a rat model of acute necrotizing pancreatitis

  2016cites this paper
• Genome-Wide Profiling of PARP1 Reveals an Interplay with Gene Regulatory Regions and DNA Methylation

  2015cites this paper
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  2015cites this paper
• Acyl-CoA-binding domain containing 3 modulates NAD+ metabolism through activating poly(ADP-ribose) polymerase 1.

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  2010cites this paper
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• [Biological activity of poly(ADP-ribose)polymerase-1].

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• Toward a Quantitative Analysis of PARP-1 and Poly(ADP-ribosyl)ation in Cellular Senescence

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• Manganese inhibits poly(ADP-ribosyl)ation in human cells: a possible mechanism behind manganese-induced toxicity?

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• Effect of PARP-1 deficiency on DNA damage and repair in human bronchial epithelial cells exposed to Benzo(a)pyrene

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  2007cites this paper
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