Chromogranin A and Derived Peptides in Health and Disease

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Journal of Molecular Neuroscience

• Publication date

  2012-03-03

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s12031-012-9728-2PMID 22388654PMCID PMC3402615
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Targeted Drug Delivery and Penetration Into Solid Tumors

  2012cited by this paper
• The novel chromogranin A‐derived serpinin and pyroglutaminated serpinin peptides are positive cardiac β‐adrenergic‐like inotropes

  2012cited by this paper
• How to improve exposure of tumor cells to drugs: promoter drugs increase tumor uptake and penetration of effector drugs.

  2012cited by this paper
• Catestatin, a chromogranin A-derived peptide, is sympathoinhibitory and attenuates sympathetic barosensitivity and the chemoreflex in rat CVLM.

  2012cited by this paper
• Role of pGlu-Serpinin, a Novel Chromogranin A-Derived Peptide in Inhibition of Cell Death

  2011cited by this paper
• Serpinin: a novel chromogranin A-derived, secreted peptide up-regulates protease nexin-1 expression and granule biogenesis in endocrine cells.

  2011cited by this paper
• The vasostatin‐1 fragment of chromogranin A preserves a quiescent phenotype in hypoxia‐driven endothelial cells and regulates tumor neovascularization

  2011cited by this paper
• The extended granin family: structure, function, and biomedical implications.

  2011cited by this paper
• Chromogranin A restricts drug penetration and limits the ability of NGR-TNF to enhance chemotherapeutic efficacy.

  2011cited by this paper
• Tumor vasculature targeting through NGR peptide-based drug delivery systems.

  2011cited by this paper
• Macrophages, inflammation, and insulin resistance.

  2010cited by this paper
• The Neuropeptide Catestatin Acts As a Novel Angiogenic Cytokine via a Basic Fibroblast Growth Factor–Dependent Mechanism

  2010cited by this paper
• Chromogranin A and the Tumor Microenvironment

  2010cited by this paper
• Granins and granin-related peptides in neuroendocrine tumours.

  2010cited by this paper
• Catestatin in rat RVLM is sympathoexcitatory, increases barosensitivity, and attenuates chemosensitivity and the somatosympathetic reflex.

  2010cited by this paper
• Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin.

  2010cited by this paper
• Direct Vasoactive Effects of the Chromogranin A (CHGA) Peptide Catestatin in Humans In Vivo

  2010cited by this paper
• Neuropeptidomic Components Generated by Proteomic Functions in Secretory Vesicles for Cell–Cell Communication

  2010cited by this paper
• Role of Reactive Oxygen Species in Hyperadrenergic Hypertension: Biochemical, Physiological, and Pharmacological Evidence From Targeted Ablation of the Chromogranin A (Chga) Gene

  2010cited by this paper
• Catestatin: a multifunctional peptide from chromogranin A.

  2010cited by this paper
• A Novel Pathway of Insulin Sensitivity in Chromogranin A Null Mice

  2009cited by this paper
• Global disturbances in autonomic function yield cardiovascular instability and hypertension in the chromogranin a null mouse.

  2009cited by this paper
• Catestatin attenuates the effects of intrathecal nicotine and isoproterenol.

  2009cited by this paper
• The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism.

  2008cited by this paper
• Naturally occurring human genetic variation in the 3'-untranslated region of the secretory protein chromogranin A is associated with autonomic blood pressure regulation and hypertension in a sex-dependent fashion.

  2008cited by this paper
• The neovasculature homing motif NGR: more than meets the eye.

  2008cited by this paper
• How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?

  2008cited by this paper
• The chromogranin A-derived vasostatins: new players in the endocrine heart.

  2008cited by this paper
• The endocrine role for chromogranin A: A prohormone for peptides with regulatory properties

  2007cited by this paper
• Catecholamine Release–Inhibitory Peptide Catestatin (Chromogranin A352–372): Naturally Occurring Amino Acid Variant Gly364Ser Causes Profound Changes in Human Autonomic Activity and Alters Risk for Hypertension

  2007cited by this paper
• The vasostatin‐I fragment of chromogranin A inhibits VEGF‐induced endothelial cell proliferation and migration

  2007cited by this paper
• Prognostic value of circulating chromogranin A and soluble tumor necrosis factor receptors in advanced nonsmall cell lung cancer

  2007cited by this paper
• The chromogranin A peptide vasostatin-I inhibits gap formation and signal transduction mediated by inflammatory agents in cultured bovine pulmonary and coronary arterial endothelial cells.

  2006cited by this paper
• Synergistic Antitumor Activity of Cisplatin, Paclitaxel, and Gemcitabine with Tumor Vasculature-Targeted Tumor Necrosis Factor-α

  2006cited by this paper
• Pancreastatin: multiple actions on human intermediary metabolism in vivo, variation in disease, and naturally occurring functional genetic polymorphism.

  2005cited by this paper
• Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog.

  2005cited by this paper
• Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology.

  2004cited by this paper
• Chromogranin A protects vessels against tumor necrosis factor α‐induced vascular leakage

  2004cited by this paper
• The chromogranin-secretogranin family.

  2003cited by this paper
• Improving chemotherapeutic drug penetration in tumors by vascular targeting and barrier alteration.

  2002cited by this paper
• Chromogranin A expression in neoplastic cells affects tumor growth and morphogenesis in mouse models.

  2002cited by this paper
• Differential binding of drugs containing the NGR motif to CD13 isoforms in tumor vessels, epithelia, and myeloid cells.

  2002cited by this paper
• Early decline in the catecholamine release-inhibitory peptide catestatin in humans at genetic risk of hypertension.

  2002cited by this paper
• Enhancement of tumor necrosis factor α antitumor immunotherapeutic properties by targeted delivery to aminopeptidase N (CD13)

  2000cited by this paper
• Pancreastatin modulates insulin signaling in rat adipocytes: mechanisms of cross-talk.

  2000cited by this paper
• Pancreastatin. Biological effects and mechanisms of action.

  2000cited by this paper
• Mechanism of cardiovascular actions of the chromogranin A fragment catestatin in vivo.

  1998cited by this paper
• Novel autocrine feedback control of catecholamine release. A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist.

  1997cited by this paper
• Characterisation of circulating chromogranin A in human cancer patients.

  1996cited by this paper
• Pancreastatin modulates glucose-stimulated insulin secretion from the perfused rat pancreas.

  1996cited by this paper
• Pancreastatin, a novel pancreatic peptide that inhibits insulin secretion

  1986cited by this paper
• Secretion of chromogranin A by peptide-producing endocrine neoplasms.

  1986cited by this paper
• Radioimmunoassay of chromogranin A in plasma as a measure of exocytotic sympathoadrenal activity in normal subjects and patients with pheochromocytoma.

  1984cited by this paper

• Catestatin in Cardiovascular Diseases

  2025cites this paper
• A complex role of chromogranin A and its peptides in inflammation, autoimmunity, and infections

  2025cites this paper
• Peptide-based drugs in immunotherapy: current advances and future prospects

  2025cites this paper
• Maternal Serum Catestatin Levels in Gestational Diabetes Mellitus: A Potential Biomarker for Risk Assessment and Diagnosis

  2025cites this paper
• Main mechanisms and clinical implications of alterations in energy expenditure state among patients with pheochromocytoma and paraganglioma: A review

  2024cites this paper
• NADPH Oxidase 3: Beyond the Inner Ear

  2024cites this paper
• Chromogranin B Protects Human Umbilical Endothelial Cells against Oxidative Stress

  2024cites this paper
• Ten-Fold Elevation of Chromogranin A Level Unrelated to a Neuroendocrine Tumor: A Case Report of the Diagnostic Interference of Proton Pump Inhibitors

  2023cites this paper
• Chromogranin A-derived peptides pancreastatin and catestatin: emerging therapeutic target for diabetes

  2023cites this paper
• Quantification of Chromogranin A and Its Fragments in Biological Fluids.

  2023cites this paper
• Chromogranin A plasma levels predict mortality in COVID-19

  2022cites this paper
• A Novel Pathway of Flavonoids Protecting against Inflammatory Bowel Disease: Modulating Enteroendocrine System

  2022cites this paper
• Functional Gly297Ser Variant of the Physiological Dysglycemic Peptide Pancreastatin is a Novel Risk Factor for Cardiometabolic Disorders.

  2021cites this paper
• The Prognostic and Predictive Role of Chromogranin A in Gastroenteropancreatic Neuroendocrine Tumors – A Single-Center Experience

  2021cites this paper
• Proteoglycan profiling of human, rat and mouse insulin-secreting cells

  2021cites this paper
• Catestatin peptide of chromogranin A as a potential new target for several risk factors management in the course of metabolic syndrome.

  2020cites this paper
• the acute

  2020cites this paper
• A systematic review of chromogranin A (CgA) and its biomedical applications, unveiling its structure-related functions

  2020cites this paper
• The associations between anxiety/depression and plasma chromogranin A among healthy workers: Results from EHOP study

  2020cites this paper
• High-Resolution mRNA and Secretome Atlas of Human Enteroendocrine Cells.

  2020cites this paper
• DIAGNOSTIC POTENTIAL OF SELECTED SALIVARY PROTEOMICS FOR AUTONOMIC NERVOUS SYSTEM ACTIVITY ASSESSMENT

  2020cites this paper
• Integrated Label-Free and 10-plex DiLeu Isobaric Tag Quantitative Methods for Profiling Changes in the Mouse Hypothalamic Neuropeptidome and Proteome: Assessment of the Impact of the Gut Microbiome.

  2020cites this paper
• Chromogranin Serves as Novel Biomarker of Endocrine and Gastric Autoimmunity.

  2020cites this paper
• Chromogranin

  2020cites this paper
• Association between preoperative Vasostatin-1 and pathological features of aggressiveness in localized nonfunctioning pancreatic neuroendocrine tumors (NF-PanNET).

  2019cites this paper
• Catestatin reverses the hypertrophic effects of norepinephrine in H9c2 cardiac myoblasts by modulating the adrenergic signaling

  2019cites this paper
• Catestatin prevents endothelial inflammation and promotes thrombus resolution in acute pulmonary embolism in mice

  2019cites this paper
• Chromogranin A pathway: from pathogenic molecule to renal disease.

  2019cites this paper
• Enteroendocrine Cells: Sensing Gut Microbiota and Regulating Inflammatory Bowel Diseases.

  2019cites this paper
• Pancreastatin inhibitor PSTi8 attenuates hyperinsulinemia induced obesity and inflammation mediated insulin resistance via MAPK/NOX3-JNK pathway.

  2019cites this paper
• Središnja medicinska knjižnica

  2019cites this paper
• Imaging Modalities: Neuropathology

  2019cites this paper
• Decreased circulating catestatin levels are associated with coronary artery disease: The emerging anti-inflammatory role.

  2019cites this paper
• Prognostic value of chromogranin A in patients with GET/NEN in the pancreas and the small intestine

  2018cites this paper
• [Oligo- and polysacharides, proteoglycans].

  2018cites this paper
• Oligo- és poliszacharidok, proteoglikánok

  2018cites this paper
• VASCULAR COGNITIVE IMPAIRMENT AND DEMENTIA: THE IMPORTANCE OF MIXED PATHOLOGIES FROM MOUSE MODELS TO HUMANS

  2018cites this paper
• Chromogranin-A and its derived peptides and their pharmacological effects during intestinal inflammation.

  2018cites this paper
• Peptides as Therapeutic Agents for Inflammatory-Related Diseases

  2018cites this paper
• Catestatin as a Target for Treatment of Inflammatory Diseases

  2018cites this paper
• The Role of the Acute Octreotide Suppression Test in Detecting Patients with Neuroendocrine Neoplasms

  2018cites this paper
• A score derived from routine biochemical parameters increases the diagnostic accuracy of chromogranin A in detecting patients with neuroendocrine neoplasms

  2018cites this paper
• Vasostatin-1: A novel circulating biomarker for ileal and pancreatic neuroendocrine neoplasms

  2018cites this paper
• Identification of proteins that bind to the neuroprotective agent neoechinulin A

  2018cites this paper
• A kromograninok, szekretograninok élettani, kórélettani és klinikai szerepéről

  2017cites this paper
• Chromogranin A Regulation of Obesity and Peripheral Insulin Sensitivity

  2017cites this paper
• Role of the neuroendocrine antimicrobial peptide catestatin in innate immunity and pain

  2017cites this paper
• Circulating chromogranin A and its fragments as diagnostic and prognostic disease markers

  2017cites this paper
• Naoling decoction restores cognitive function by inhibiting the neuroinflammatory network in a rat model of Alzheimer’s disease

  2017cites this paper
• Chromofungin (CHR: CHGA47–66) is downregulated in persons with active ulcerative colitis and suppresses pro‐inflammatory macrophage function through the inhibition of NF‐&kgr;B signaling

  2017cites this paper
• Reprogramming of Oncogene Expression in Gingival Mesenchymal Stem Cells Following Long-Term Culture In Vitro

  2017cites this paper
• Biological Roles of the Eclectic Chromogranin-A-derived Peptide Catestatin.

  2017cites this paper
• [Physiological, pathophysiological and clinical significance of chromogranins/secretogranins].

  2017cites this paper
• Chromogranins: from Cell Biology to Physiology and Biomedicine

  2017cites this paper
• Chromofungin Ameliorates the Progression of Colitis by Regulating Alternatively Activated Macrophages

  2017cites this paper
• Correlation study on chromogranin A genetic polymorphism and prognosis of critically ill patients☆,☆☆

  2017cites this paper
• Human milk oligosaccharide supplementation did not affect gut development in the healthy neonatal piglet

  2017cites this paper
• Chromogranin A in Endothelial Homeostasis and Angiogenesis

  2017cites this paper
• Serpinin Peptides: Tissue Distribution and Functions

  2017cites this paper
• Inhibition of chronic lymphocytic leukemia progression by full-length chromogranin A and its N-terminal fragment in mouse models

  2016cites this paper
• Chapter 3 – Control of Hormone Secretion

  2016cites this paper
• Chromogranin A as biomarker in diabetes.

  2016cites this paper
• Identification of novel loci affecting circulating chromogranins and related peptides

  2016cites this paper
• MicroRNA response of inhalation exposure to hexanal in lung tissues from Fischer 344 rats

  2016cites this paper
• Circulating tumor markers in patients with neuroendocrine tumors - a clinical perspective

  2015cites this paper
• Altered Chromogranin A Circulating Levels in Meniere's Disease

  2015cites this paper
• "Unclassical" Combination of Smell Dysfunction, Altered Abdominal Nociception and Human Hypertension Associated "Classical" Adrenal-Augmentation.

  2015cites this paper
• Examination of Epigenetic and other Molecular Factors Associated with mda-9/Syntenin Dysregulation in Cancer Through Integrated Analyses of Public Genomic Datasets.

  2015cites this paper
• Preliminary assessment of measurments chromogranin A in patients with gastro – entero-pancreatic neuroendocrine neoplasms

  2015cites this paper
• Influence of food intervention on enteric nervous system and enteroendocrine cells development in a small for gestational age piglet model

  2015cites this paper
• Comparison of chromogranin A (CgA) levels in serum and plasma (EDTA2K) and the respective reference ranges in healthy males.

  2015cites this paper
• Metastasising hepatic neuroendocrine carcinoma in a pygmy goat (Capra hircus hircus)

  2015cites this paper
• Chromogranin A as a biomarker in cardiovascular disease.

  2014cites this paper
• Chromogranin A: a paradoxical player in angiogenesis and vascular biology

  2014cites this paper
• Biological function and clinical relevance of chromogranin A and derived peptides

  2014cites this paper
• Catestatin decreases macrophage function in two mouse models of experimental colitis.

  2014cites this paper
• The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure

  2014cites this paper
• Catestatin-like immunoreactivity in the rat eye.

  2014cites this paper
• Cardio-vascular activity of catestatin: interlocking the puzzle pieces.

  2014cites this paper
• Apoptosis, ANUP, Chromogranin A, PGP 9.5, Endothelins and VEGF in Acquired Heart Diseases: Review of Literature

  2014cites this paper
• High-grade KIT-negative sarcoma of the small bowel in a patient with chronic myeloid leukemia receiving long-term tyrosine kinase inhibitors.

  2013cites this paper
• Gastric secretion

  2013cites this paper
• Neuroendocrine Stress Response after Burn Trauma

  2013cites this paper
• Novel autoantigens in type 1 diabetes.

  2013cites this paper
• Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 908 Neuroendocrine Stress Response after Burn Trauma

  2013cites this paper
• ANGPTL4 is produced by entero-endocrine cells in the human intestinal tract

  2013cites this paper
• Cerebrospinal fluid levels of chromogranin A in the treatment-naïve early stage Parkinson’s disease: a pilot study

  2013cites this paper
• Expression variations of chromogranin A and α1,2,4 GABA(A)Rs in discrete limbic and brainstem areas rescue cardiovascular alterations.

  2013cites this paper
• Mass spectrometry identification of granins and other proteins secreted by neuroblastoma cells

  2013cites this paper
• Naturally Occurring Variants of the Dysglycemic Peptide Pancreastatin

  2013cites this paper
• Functional Genetic Variants of the Catecholamine-Release-Inhibitory Peptide Catestatin in an Indian Population

  2012influential citation
• Cellular mechanisms for the biogenesis and transport of synaptic and dense-core vesicles.

  2012cites this paper