Novel Mechanisms of Disease: Network Biology and MicroRNA Signaling in Pulmonary Hypertension

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/978-3-319-23594-3_7
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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  2015cited by this paper
• Role of epigenetics in pulmonary hypertension.

  2014cited by this paper
• MicroRNA-124 Controls the Proliferative, Migratory, and Inflammatory Phenotype of Pulmonary Vascular Fibroblasts

  2014cited by this paper
• Correction.

  2014cited by this paper
• Endothelial Apoptosis in Pulmonary Hypertension Is Controlled by a microRNA/Programmed Cell Death 4/Caspase-3 Axis

  2014cited by this paper
• Regulation of microRNA biogenesis

  2014cited by this paper
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  2013cited by this paper
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  2013cited by this paper
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  2013cited by this paper
• Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension.

  2013cited by this paper
• Hypoxia Mediates Mutual Repression between microRNA-27a and PPARγ in the Pulmonary Vasculature

  2013cited by this paper
• Reconstructing dynamic microRNA-regulated interaction networks

  2013cited by this paper
• Diversifying microRNA sequence and function

  2013cited by this paper
• miR-26a linked to pulmonary hypertension by global assessment of circulating extracellular microRNAs.

  2013cited by this paper
• miRBase: annotating high confidence microRNAs using deep sequencing data

  2013cited by this paper
• miRNA–transcription factor interactions: a combinatorial regulation of gene expression

  2013cited by this paper
• Sustained-input switches for transcription factors and microRNAs are central building blocks of eukaryotic gene circuits

  2013cited by this paper
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  2013cited by this paper
• Relevant issues in the pathology and pathobiology of pulmonary hypertension.

  2013cited by this paper
• A brief overview of mouse models of pulmonary arterial hypertension: problems and prospects.

  2012cited by this paper
• The monocrotaline model of pulmonary hypertension in perspective.

  2012cited by this paper
• DNA Damage Induces NF-κB-dependent MicroRNA-21 Up-regulation and Promotes Breast Cancer Cell Invasion*

  2012cited by this paper
• Novel Modeling of Combinatorial miRNA Targeting Identifies SNP with Potential Role in Bone Density

  2012cited by this paper
• A Role for miR-145 in Pulmonary Arterial Hypertension: Evidence From Mouse Models and Patient Samples

  2012cited by this paper
• miR-210 has an antiapoptotic effect in pulmonary artery smooth muscle cells during hypoxia.

  2012cited by this paper
• Analytical challenges and technical limitations in assessing circulating MiRNAs

  2012cited by this paper
• miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling.

  2012cited by this paper
• MicroRNA-21 Integrates Pathogenic Signaling to Control Pulmonary Hypertension: Results of a Network Bioinformatics Approach

  2012cited by this paper
• MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship

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• Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease?

  2012cited by this paper
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  2012cited by this paper
• Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma

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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
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  2011cited by this paper
• Altered MicroRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8.

  2011cited by this paper
• Role for miR-204 in human pulmonary arterial hypertension

  2011cited by this paper
• A novel murine model of severe pulmonary arterial hypertension.

  2011cited by this paper
• Disruption of the Apelin-APJ System Worsens Hypoxia-Induced Pulmonary Hypertension

  2011cited by this paper
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  2010cited by this paper
• Genome-wide dissection of microRNA functions and cotargeting networks using gene set signatures.

  2010cited by this paper
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  2010cited by this paper
• Reversible or irreversible remodeling in pulmonary arterial hypertension.

  2010cited by this paper
• Mammalian microRNAs predominantly act to decrease target mRNA levels

  2010cited by this paper
• MicroRNA expression in human airway smooth muscle cells: role of miR-25 in regulation of airway smooth muscle phenotype.

  2010cited by this paper
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  2010cited by this paper
• MicroRNA‐21 plays a Role in Hypoxia‐mediated Pulmonary Artery Smooth Muscle Cell Proliferation and Migration

  2010cited by this paper
• Mammalian microRNAs: experimental evaluation of novel and previously annotated genes.

  2010cited by this paper
• Dynamic Changes in Lung MicroRNA Profiles During the Development of Pulmonary Hypertension due to Chronic Hypoxia and Monocrotaline

  2010cited by this paper
• MicroRNA‐204/211 alters epithelial physiology

  2010cited by this paper
• Bone morphogenetic protein type II receptor mutations causing protein misfolding in heritable pulmonary arterial hypertension.

  2010cited by this paper
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  2010cited by this paper
• Updated clinical classification of pulmonary hypertension.

  2009cited by this paper
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  2009cited by this paper
• Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation.

  2009cited by this paper
• MicroRNAs: Target Recognition and Regulatory Functions

  2009cited by this paper
• Interleukin-6 Modulates the Expression of the Bone Morphogenic Protein Receptor Type II Through a Novel STAT3–microRNA Cluster 17/92 Pathway

  2009cited by this paper
• The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease

  2009cited by this paper
• Fibronectin Is an Important Regulator of Flow-Induced Vascular Remodeling

  2009cited by this paper
• MicroRNAs: Control and Loss of Control in Human Physiology and Disease

  2009cited by this paper
• Many roads to maturity: microRNA biogenesis pathways and their regulation

  2009cited by this paper
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  2008cited by this paper
• The impact of microRNAs on protein output

  2008cited by this paper
• Most mammalian mRNAs are conserved targets of microRNAs.

  2008cited by this paper
• Widespread changes in protein synthesis induced by microRNAs

  2008cited by this paper
• MicroRNA-210 Modulates Endothelial Cell Response to Hypoxia and Inhibits the Receptor Tyrosine Kinase Ligand Ephrin-A3*

  2008cited by this paper
• Pathobiology of pulmonary hypertension.

  2007cited by this paper
• MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals.

  2007cited by this paper
• Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation

  2007cited by this paper
• Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer.

  2007cited by this paper
• A MicroRNA Signature of Hypoxia

  2006cited by this paper
• RNA polymerase III transcribes human microRNAs

  2006cited by this paper
• Role of the adventitia in pulmonary vascular remodeling.

  2006cited by this paper
• Transforming growth factor-beta1 induces transdifferentiation of fibroblasts into myofibroblasts in hypoxic pulmonary vascular remodeling.

  2006cited by this paper
• NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses

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• The Widespread Impact of Mammalian MicroRNAs on mRNA Repression and Evolution

  2005cited by this paper
• miRBase: microRNA sequences, targets and gene nomenclature

  2005cited by this paper
• Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes.

  2005cited by this paper
• Cellular and molecular pathobiology of pulmonary arterial hypertension.

  2004cited by this paper
• Processing of primary microRNAs by the Microprocessor complex

  2004cited by this paper
• The Microprocessor complex mediates the genesis of microRNAs

  2004cited by this paper
• MicroRNA genes are transcribed by RNA polymerase II

  2004cited by this paper
• The nuclear RNase III Drosha initiates microRNA processing

  2003cited by this paper
• A uniform system for microRNA annotation.

  2003cited by this paper
• Hypoxic activation of adventitial fibroblasts: role in vascular remodeling.

  2002cited by this paper
• MicroRNA maturation: stepwise processing and subcellular localization

  2002cited by this paper
• The pathobiology of pulmonary hypertension. Endothelium.

  2001cited by this paper
• Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha.

  1999cited by this paper
• Three-dimensional reconstruction of pulmonary arteries in plexiform pulmonary hypertension using cell-specific markers. Evidence for a dynamic and heterogeneous process of pulmonary endothelial cell growth.

  1999cited by this paper
• The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14.

  1993cited by this paper
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  year unknowncited by this paper

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  2020cites this paper
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  2018cites this paper
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