Growth differentiation factor-15: induction in liver injury through p53 and tumor necrosis factor-independent mechanisms.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Surgical Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.JSS.2005.07.036PMID 16154591
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• GROWTH DIFFERENTIATION FACTOR-15/MACROPHAGE INHIBITORY CYTOKINE-1 INDUCTION AFTER KIDNEY AND LUNG INJURY

  2005cited by this paper
• Expression of NAG-1, a Transforming Growth Factor-β Superfamily Member, by Troglitazone Requires the Early Growth Response Gene EGR-1*

  2004cited by this paper
• Massive liver growth in mice induced by systemic interleukin 6 administration

  2003cited by this paper
• Genotoxic profiling of MCF-7 breast cancer cell line elucidates gene expression modifications underlying toxicity of the anticancer drug 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole.

  2003cited by this paper
• Overexpression of NSAID-Activated Gene Product in Prostate Cancer

  2003cited by this paper
• Gene modulation by Cox-1 and Cox-2 specific inhibitors in human colorectal carcinoma cancer cells.

  2003cited by this paper
• Nonsteroidal anti‐inflammatory drug‐activated gene (NAG‐1) is induced by genistein through the expression of p53 in colorectal cancer cells

  2003cited by this paper
• Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer.

  2003cited by this paper
• From TGF- to Cancer Therapy

  2003cited by this paper
• Differential regulation of nonsteroidal anti-inflammatory drug-activated gene in normal human tracheobronchial epithelial and lung carcinoma cells by retinoids.

  2003cited by this paper
• Macrophage inhibitory cytokine-1 induces the invasiveness of gastric cancer cells by up-regulating the urokinase-type plasminogen activator system.

  2003cited by this paper
• Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice.

  2003cited by this paper
• MIC-1 serum level and genotype: associations with progress and prognosis of colorectal carcinoma.

  2003cited by this paper
• Induction of MIC-1/growth differentiation factor-15 following bile duct injury

  2003cited by this paper
• Growth Differentiation Factor-15 Prevents Low Potassium-induced Cell Death of Cerebellar Granule Neurons by Differential Regulation of Akt and ERK Pathways*

  2003cited by this paper
• From TGF-beta to cancer therapy.

  2003cited by this paper
• Cytostatic and apoptotic actions of TGF-β in homeostasis and cancer

  2003cited by this paper
• Anoxia induces macrophage inhibitory cytokine-1 (MIC-1) in glioblastoma cells independently of p53 and HIF-1

  2002cited by this paper
• Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53.

  2002cited by this paper
• Diallyl disulfide (DADS) induces the antitumorigenic NSAID-activated gene (NAG-1) by a p53-dependent mechanism in human colorectal HCT 116 cells.

  2002cited by this paper
• Expression and regulation of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) in human and mouse tissue.

  2002cited by this paper
• Role of immediate early gene expression in cortical morphogenesis and plasticity.

  2002cited by this paper
• Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities.

  2001cited by this paper
• Secreted and cell surface genes expressed in benign and malignant colorectal tumors.

  2001cited by this paper
• Molecular Cloning and Characterization of Human Nonsteroidal Anti-inflammatory Drug-activated Gene Promoter

  2001cited by this paper
• Cyclooxygenase Inhibitors Regulate the Expression of a TGF-β Superfamily Member That Has Proapoptotic and Antitumorigenic Activities

  2001cited by this paper
• Cytokine-Responsive Gene-2/IFN-Inducible Protein-10 Expression in Multiple Models of Liver and Bile Duct Injury Suggests a Role in Tissue Regeneration1

  2001cited by this paper
• Characterization of Growth-Differentiation Factor 15, a Transforming Growth Factor β Superfamily Member Induced following Liver Injury

  2000cited by this paper
• Placental Transforming Growth Factor-β Is a Downstream Mediator of the Growth Arrest and Apoptotic Response of Tumor Cells to DNA Damage and p53 Overexpression*

  2000cited by this paper
• PTGF-β, a type β transforming growth factor (TGF-β) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-β signaling pathway

  2000cited by this paper
• Growth/Differentiation Factor-15/Macrophage Inhibitory Cytokine-1 Is a Novel Trophic Factor for Midbrain Dopaminergic Neurons In Vivo

  2000cited by this paper
• Profile of gene expression regulated by induced p53: connection to the TGF‐β family

  2000cited by this paper
• PTGF-beta, a type beta transforming growth factor (TGF-beta) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathway.

  2000cited by this paper
• MAP kinase-mediated signalling to nucleosomes and immediate-early gene induction.

  1999cited by this paper
• Expression of a novel member of the TGF-β superfamily, growth/differentiation factor-15/macrophage-inhibiting cytokine-1 (GDF-15/MIC-1) in adult rat tissues

  1999cited by this paper
• Cloning and Characterization of a Novel Member of the Transforming Growth Factor-β/Bone Morphogenetic Protein Family*

  1998cited by this paper
• MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily.

  1997cited by this paper
• Human cDNA encoding a novel TGF-beta superfamily protein highly expressed in placenta.

  1997cited by this paper
• PLAB, a novel placental bone morphogenetic protein.

  1997cited by this paper
• Transient down-regulation of inhibin-betaC expression following partial hepatectomy.

  1997cited by this paper
• Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

  1996cited by this paper
• Tumor suppressor activity of the TGF-beta pathway in human cancers.

  1996cited by this paper
• Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways

  1996cited by this paper
• Tumor suppressor activity of the TGF-β pathway in human cancers

  1996cited by this paper
• Missense mutations of the transforming growth factor beta type II receptor in human head and neck squamous carcinoma cells.

  1995cited by this paper
• c-myc, c-fos, and c-jun regulation in the regenerating livers of normal and H-2K/c-myc transgenic mice

  1990cited by this paper

• GDF‐15 Levels in Cirrhosis Are Linked to Hepatic Fibrogenesis, Bacterial Translocation, and Worse Clinical Outcomes

  2026cites this paper
• Levels of Growth Differentiation Factor 15 Correlated with Metabolic Dysfunction-Associated Steatotic Liver Disease in Children

  2025cites this paper
• Hepatic Estrogen-Related Receptor gamma is a Key Regulator of GDF15 Production in Acute and Chronic Liver Injury.

  2025cites this paper
• Growth differentiation factor 15: Emerging role in liver diseases.

  2024cites this paper
• Growth differentiation factor 15 (GDF-15) in endocrinology

  2023cites this paper
• Growth differentiation factor 15 is dispensable for acetaminophen‐induced liver injury in mice

  2023cites this paper
• Multidimensional Approach of Heart Failure Diagnosis and Prognostication Utilizing Cardiac Imaging with Biomarkers

  2022cites this paper
• The Potential Role of Growth Differentiation Factor 15 in COVID-19: A Corollary Subjective Effect or Not?

  2022cites this paper
• Characterization of atherosclerotic plaques in blood vessels with low oxygenated blood and blood pressure (Pulmonary trunk): role of growth differentiation factor-15 (GDF-15)

  2021cites this paper
• Cytokines, Chemokines, and Inflammation in Pulmonary Arterial Hypertension.

  2021cites this paper
• Oxidative Phosphorylation Dysfunction Modifies the Cell Secretome

  2020cites this paper
• Conserved function of zebrafish (Danio rerio) Gdf15 as a sepsis tolerance mediator.

  2020cites this paper
• Association of Exhaled Carbon Monoxide With Ideal Cardiovascular Health, Circulating Biomarkers, and Incidence of Heart Failure in the Framingham Offspring Study

  2020cites this paper
• Increased concentrations of growth differentiation factor-15 in children with Kawasaki disease.

  2020cites this paper
• Growth differentiation factor 15: A novel biomarker with high clinical potential

  2019cites this paper
• Implications of Mitochondrial Unfolded Protein Response and Mitokines: A Perspective on Fatty Liver Diseases

  2019cites this paper
• Biomarkers in heart failure: the past, current and future

  2019cites this paper
• GDF-15: A Multifunctional Modulator and Potential Therapeutic Target in Cancer.

  2019cites this paper
• Resveratrol Improves Recovery and Survival of Diet-Induced Obese Mice Undergoing Extended Major (80%) Hepatectomy

  2018cites this paper
• Angiogenesis enhanced by treatment damage to hepatocellular carcinoma through the release of GDF15

  2018cites this paper
• Growth Differentiation Factor-15 Is a Predictor of Mortality in Critically Ill Patients with Sepsis

  2017cites this paper
• miR-542: a novel regulator for muscle mass and function

  2017cites this paper
• GDF15 deficiency exacerbates chronic alcohol- and carbon tetrachloride-induced liver injury

  2017cites this paper
• Epidermal growth factor receptor restoration rescues the fatty liver regeneration in mice.

  2017cites this paper
• Growth Differentiation Factor 15 May Predict Mortality of Peripheral and Coronary Artery Diseases and Correlate with Their Risk Factors

  2017cites this paper
• Disturbed iron metabolism in erythropoietic protoporphyria and association of GDF15 and gender with disease severity

  2017cites this paper
• Biomarkers for diet in cancer prevention studies

  2016cites this paper
• GDF-15 Is Elevated in Children with Mitochondrial Diseases and Is Induced by Mitochondrial Dysfunction

  2016cites this paper
• TGF beta Superfamily Cytokine MIC-1/GDF15 in Health and Inflammatory Diseases

  2016cites this paper
• Increased Serum Level of Growth Differentiation Factor 15 (GDF-15) is Associated with Coronary Artery Disease.

  2016cites this paper
• Chirurgie cardiaque sous circulation extra-corporelle et ses biomarqueurs : rôle du Growth / Différentiation Factor 15 (GDF 15) : études cliniques

  2016cites this paper
• Growth differentiation factor 15 (GDF‐15) in patients admitted for acute heart failure: results from the RELAX‐AHF study

  2015cites this paper
• The divergent roles of growth differentiation factor-15 (GDF-15) in benign and malignant skin pathologies

  2015cites this paper
• The H6D genetic variation of GDF15 is associated with genesis, progress and prognosis in colorectal cancer.

  2015cites this paper
• Growth‐differentiation factor 15 and osteoprotegerin in acute myocardial infarction complicated by cardiogenic shock: a biomarker substudy of the IABP‐SHOCK II‐trial

  2014cites this paper
• Acute exercise in elite rugby players increases the circulating level of the cardiovascular biomarker GDF-15

  2014cites this paper
• Gene expression responses in human lung fibroblasts exposed to alpha particle radiation.

  2014cites this paper
• Troubleshooting methods for microarray gene expression analysis in the onset of diabetic kidney disease.

  2013cites this paper
• Growth differentiation factor 15 impairs aortic contractile and relaxing function through altered caveolar signaling of the endothelium.

  2013cites this paper
• The multiple facets of the TGF-β family cytokine growth/differentiation factor-15/macrophage inhibitory cytokine-1.

  2013cites this paper
• Growth Differentiation Factor 15 in Heart Failure: An Update

  2012cites this paper
• Inflammation-associated regulation of the macrophage inhibitory cytokine (MIC-1) gene in prostate cancer.

  2012cites this paper
• Growth differentiation factor-15 upregulates interleukin-6 to promote tumorigenesis of prostate carcinoma PC-3 cells.

  2012cites this paper
• AUTHOR COPY ONLY Growth differentiation factor-15 upregulates interleukin-6 to promote tumorigenesis of prostate carcinoma PC-3 cells

  2012cites this paper
• The role of growth differentiaton factor 15 in diabetic kidney injury

  2012cites this paper
• Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15) Slows Cancer Development but Increases Metastases in TRAMP Prostate Cancer Prone Mice

  2012cites this paper
• Profile of stress and toxicity gene expression in human hepatic cells treated with Efavirenz.

  2012cites this paper
• GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells

  2011cites this paper
• Hepatic gene expression profiling of 5'-AMP-induced hypometabolism in mice.

  2011cites this paper
• Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy

  2011cites this paper
• The TGF-β superfamily cytokine, MIC-1/GDF15: A pleotrophic cytokine with roles in inflammation, cancer and metabolism

  2011cites this paper
• STAT3 Activation in Skeletal Muscle Links Muscle Wasting and the Acute Phase Response in Cancer Cachexia

  2011cites this paper
• Role of Nag-1 and p75NTR in non-steroidal anti-inflammatory drug inhibition of prostate cancer cell migration

  2011cites this paper
• Loss of GDF-15 abolishes Sulindac chemoprevention in the ApcMin/+ mouse model of intestinal cancer

  2010influential citation
• Association of macrophage inhibitory cytokine-1 with nutritional status, body composition and bone mineral density in patients with anorexia nervosa: the influence of partial realimentation

  2010cites this paper
• Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine‐1 in cancer

  2010influential citation
• Influence of inflammation and aging on macrophage inhibitory cytokine-1 gene expression in rat ventral prostate.

  2009cites this paper
• Secretion as an Adipokine by Human Adipocytes Identification of Macrophage Inhibitory Cytokine-1 in Adipose Tissue and Its

  2009cites this paper
• Growth/differentiation factor-15 inhibits differentiation into osteoclasts--a novel factor involved in control of osteoclast differentiation.

  2009cites this paper
• Identification of macrophage inhibitory cytokine-1 in adipose tissue and its secretion as an adipokine by human adipocytes.

  2009cites this paper
• Growth differentiation factor 15, a novel acute phase response gene in Japanese flounder, Paralichthys olivaceus.

  2009cites this paper
• Differences in Gene Expression Profiles Reflecting Differences in Drug Sensitivity to Acetaminophen in Normal and Transformed Hepatic Cell Lines In vitro

  2009cites this paper
• Growth differentiation factor-15 in idiopathic pulmonary arterial hypertension.

  2008cites this paper
• Effect of in vivo loss of GDF-15 on hepatocellular carcinogenesis

  2008cites this paper
• GDF15 triggers homeostatic proliferation of acid-secreting collecting duct cells.

  2008cites this paper
• Adipocyte culture medium stimulates production of macrophage inhibitory cytokine 1 in MDA-MB-231 cells.

  2008cites this paper
• Open Access Research

  2008cites this paper
• Identification of Differentially Expressed Genes (DEGs) by Malachite Green in HepG2 Cells

  2008cites this paper
• Transcriptomic assessment of quinone mediated hepatic oxidative stress

  2007cites this paper
• Current World Literature

  2006cites this paper
• Mediators of rat ischemic hepatic preconditioning after cold preservation identified by microarray analysis

  2006cites this paper