SCIENCE@home

Comment on Retinal findings of COVID-19 patients using ocular coherence tomography angiography two to three months after infection: Ocular appearance recovered COVID-19 patient

Pradeep Kumar Panigrahi,Suchismita Mishra

Published 2020 in Photodiagnosis and Photodynamic Therapy

ABSTRACT

This study aimed to assess the repair of complete surgical tibial fractures fi xed with internal rigid fi xation (IRF) associated or not to the use of mineral trioxide aggregate (MTA) cement and treated or not with laser ( λ =780nm, infrared) or LED ( λ =850 ± 10nm, infrared) lights, 142.8J/cm 2 per treatment, by means of Raman spectroscopy. Open surgical tibial fractures were created on 18 rabbits (6 groups of 3 animals per group, ∼ 8 months old) and fractures were fi xed with IRF. Three groups were grafted with MTA. The groups of IRF and IRF+MTA that received laser or LED were irradiated every other day during 15 days. Animals were sacri fi ced after 30 days, being the tibia surgically removed. Raman spectra were collected via the probe at the defect site in fi ve points, resulting in 15 spectra per group (90 spectra in the dataset). Spectra were collected at the same day to avoid changes in laser power and experimental setup. The ANOVA general linear model showed that the laser irradiation of tibial bone fractures fi xed with IRF and grafted with MTA had signi fi cant in fl uence in the content of phosphate (peak ∼ 960 cm -1 ) and carbonated (peak ∼ 1,070cm -1 ) hydroxyapatites as well as collagen (peak 1,452cm -1 ). Also, peaks of calcium carbonate (1,088cm -1 ) were found in the groups grafted with MTA. Based on the Raman spectroscopic data collected in this study, MTA has been shown to improve the repair of complete tibial fractures treated with IRF, with an evident increase of collagen matrix synthesis, and development of a sca ff old of hydroxyapatite-like calcium carbonate with subsequent deposition of phosphate hydroxyapatite.

PUBLICATION RECORD

CITATION MAP

EXTRACTION MAP

CLAIMS

  • No claims are published for this paper.

CONCEPTS

  • No concepts are published for this paper.

REFERENCES

Showing 1-47 of 47 references · Page 1 of 1

CITED BY

Showing 1-65 of 65 citing papers · Page 1 of 1