Renoprotective effect of total glucosides of paeony (TGP) and its mechanism in experimental diabetes.

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Journal of Pharmacological Sciences

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1254/JPHS.08112FPPMID 19151544
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Paeoniflorin suppresses inflammatory mediator production and regulates G protein-coupled signaling in fibroblast – like synoviocytes of collagen induced arthritic rats

  2008cited by this paper
• Elucidation of Danzhixiaoyao Wan and Its Constituent Herbs on Antioxidant Activity and Inhibition of Nitric Oxide Production

  2007cited by this paper
• Transcriptional suppression of nephrin in podocytes by macrophages: Roles of inflammatory cytokines and involvement of the PI3K/Akt pathway

  2007cited by this paper
• [Effects of paeoniflorin on pathological changes in global brain ischemia model rats].

  2007cited by this paper
• Protective effects of keishibukuryogan on the kidney of spontaneously diabetic WBN/Kob rats.

  2007cited by this paper
• Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-κB activation

  2007cited by this paper
• Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation.

  2007cited by this paper
• Effects and mechanisms of Paeoniflorin, a bioactive glucoside from paeony root, on adjuvant arthritis in rats

  2007cited by this paper
• Leukocyte recruitment and vascular injury in diabetic nephropathy.

  2006cited by this paper
• The antioxidative effects of astragalus saponin I protect against development of early diabetic nephropathy.

  2006cited by this paper
• PROTECTIVE EFFECT OF PAEONIFLORIN ON IMMUNOLOGICAL LIVER INJURY INDUCED BY BACILLUS CALMETTE‐GUERIN PLUS LIPOPOLYSACCHARIDE: MODULATION OF TUMOUR NECROSIS FACTOR‐α AND INTERLEUKIN‐6 mRNA

  2006cited by this paper
• Prevention of early renal injury by mycophenolate mofetil and its mechanism in experimental diabetes.

  2006cited by this paper
• The pathobiology of diabetic complications: a unifying mechanism.

  2005cited by this paper
• Linking metabolism and immunology: diabetic nephropathy is an inflammatory disease.

  2005cited by this paper
• Effects and mechanisms of total glucosides of paeony on joint damage in rat collagen-induced arthritis

  2005cited by this paper
• Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic rats

  2005cited by this paper
• Total glucosides of paeony suppresses adjuvant arthritis in rats and intervenes cytokine-signaling between different types of synoviocytes.

  2005cited by this paper
• Erythromycin ameliorates renal injury via anti-inflammatory effects in experimental diabetic rats

  2005cited by this paper
• Methotrexate prevents renal injury in experimental diabetic rats via anti-inflammatory actions.

  2005cited by this paper
• The role of inflammation as a pathogenic factor in the development of renal disease in diabetes

  2005cited by this paper
• Effects of total glucosides of peony on immunological hepatic fibrosis in rats.

  2005cited by this paper
• Protective effects of Astragalus saponin I on early stage of diabetic nephropathy in rats.

  2004cited by this paper
• Intercellular adhesion molecule-1-deficient mice are resistant against renal injury after induction of diabetes

  2004cited by this paper
• Expression of podocyte-associated molecules in acquired human kidney diseases.

  2003cited by this paper
• Mycophenolate mofetil prevents the development of glomerular injury in experimental diabetes.

  2003cited by this paper
• Intercellular adhesion molecule-1-deficient mice are resistant against renal injury after induction of diabetes.

  2003cited by this paper
• Peroxynitrite induces formation of N( epsilon )-(carboxymethyl) lysine by the cleavage of Amadori product and generation of glucosone and glyoxal from glucose: novel pathways for protein modification by peroxynitrite.

  2002cited by this paper
• Modulation of nephrin in the diabetic kidney: association with systemic hypertension and increasing albuminuria

  2002cited by this paper
• An Oral Adsorbent Downregulates Renal Expression of Genes That Promote Interstitial Inflammation and Fibrosis in Diabetic Rats

  2002cited by this paper
• Irbesartan normalises the deficiency in glomerular nephrin expression in a model of diabetes and hypertension

  2001cited by this paper
• Increased Expression of Intercellular Adhesion Molecule-1 (ICAM-1) in Diabetic Rat Glomeruli: Glomerular Hyperfiltration Is a Potential Mechanism of ICAM-1 Upregulation

  1997cited by this paper
• Hyperglycemia and Diabetic Kidney Disease: The Case for Transforming Growth Factor–β as a Key Mediator

  1995cited by this paper
• [A review on the pharmacology of Paeonia lactiflora and its chemical components].

  1985cited by this paper
• A review on the pharmacology of Paeonia lactiflora and its chemical components

  1985cited by this paper

• Paeoniflorin: a review of its pharmacology, pharmacokinetics and toxicity in diabetes

  2025cites this paper
• Age-dependent variations in bioactive compounds in the roots of Himalayan peony (Paeonia emodi Royle)

  2023cites this paper
• Total Glucosides of Paeony Attenuates Ulcerative Colitis via Inhibiting TLR4/NF-κB Signaling Pathway.

  2022cites this paper
• Mechanisms of Zhenwu decoction for the treatment of renal fibrosis at various stages: What is the role of Corynebacterium?

  2022cites this paper
• Total Glucosides of Paeony Inhibited Autophagy and Improved Acute Kidney Injury Induced by Ischemia-Reperfusion via the lncRNA TUG1/miR-29a/PTEN Axis

  2021cites this paper
• DDDT_A_286606 2229..2242

  2021cites this paper
• Unraveling the Immunopathogenesis and Genetic Variants in Vasculitis Toward Development of Personalized Medicine

  2021cites this paper
• Total Glucosides of Paeony Alleviate Cell Apoptosis and Inflammation by Targeting the Long Noncoding RNA XIST/MicroRNA-124-3p/ITGB1 Axis in Renal Ischemia/Reperfusion Injury

  2020cites this paper
• Mechanisms of Herbal Nephroprotection in diabetes mellitus

  2020influential citation
• Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony.

  2019cites this paper
• Total glucosides of paeony (TGP) extracted from Radix Paeoniae Alba exerts neuroprotective effects in MPTP-induced experimental parkinsonism by regulating the cAMP/PKA/CREB signaling pathway.

  2019cites this paper
• Tripterygium wilfordii mitigates hyperglycemia-induced upregulated Wnt/β-catenin expression and kidney injury in diabetic rats

  2018cites this paper
• Hepatoprotective effect of peony total glucosides and the underlying mechanisms in diabetic rats

  2017cites this paper
• Study on the interaction of paeoniflorin with human serum albumin (HSA) by spectroscopic and molecular docking techniques

  2017cites this paper
• Total glucosides of paeony ameliorates TNBS‑induced colitis by modulating differentiation of Th17/Treg cells and the secretion of cytokines.

  2017cites this paper
• Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation

  2017cites this paper
• Renoprotective Effects of Total Glucosides from Paeony against Nephrotoxicity Induced by Total Alkaloids from Semen Strychni

  2017cites this paper
• A Pharmacological Review of Bioactive Constituents of Paeonia lactiflora Pallas and Paeonia veitchii Lynch

  2016cites this paper
• Total Glucosides of Paeony Promote Intestinal Motility in Slow Transit Constipation Rats through Amelioration of Interstitial Cells of Cajal

  2016cites this paper
• Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus

  2016cites this paper
• Effect of total glucosides of paeonia on TGF-β 1 and ICAM-1 expression in the kidney of diabetic rats

  2016cites this paper
• Total glucosides of paeony (TGP) inhibits the production of inflammatory cytokines in oral lichen planus by suppressing the NF-κB signaling pathway.

  2016cites this paper
• TGP attenuates endoplasmic reticulum stress and regulates the expression of thioredoxin-interacting protein in the kidneys of diabetic rats.

  2016cites this paper
• Paeoniflorin selectively inhibits LPS-provoked B-cell function.

  2015cites this paper
• Paeoniflorin protects HUVECs from AGE-BSA-induced injury via an autophagic pathway by acting on the RAGE.

  2015cites this paper
• Angiostatin prevents IL-1β-induced down-regulation of eNOS expression by inhibiting the NF-κB cascade.

  2015cites this paper
• Production of paeoniflorin and albiflorin by callus tissue culture of Paeonia lactiflora Pall

  2015cites this paper
• The Anticancer Mechanism of an Approved Disease Modifying Herb Medicine:Total Glucosides of Paeony Target both EGFR and HER-2 in Lung Cancer Cell Lines

  2014cites this paper
• Total glucosides of paeony attenuate renal tubulointerstitial injury in STZ-induced diabetic rats: role of Toll-like receptor 2.

  2014cites this paper
• An unusual case of Sweet syndrome in a child: overlapping presentation with erythema elevatum diutinum.

  2014cites this paper
• Effects of total glucosides of paeony on immune regulatory toll-like receptors TLR2 and 4 in the kidney from diabetic rats.

  2014cites this paper
• Increased Macrophage Activation Inhibited by Tacrolimus in the Kidney of Diabetic Rats

  2014cites this paper
• Protective Effect of Paeonia anomala Extracts and Constituents against tert-Butylhydroperoxide-Induced Oxidative Stress in HepG2 Cells

  2013cites this paper
• Effects of total glucosides of paeony for delaying onset of Sjogren's syndrome: an animal study.

  2013cites this paper
• Protection of H9c2 rat cardiomyoblasts against oxidative insults by total paeony glucosides from Radix Paeoniae Rubrae.

  2013cites this paper
• Rapid screening and quantification of sulfonate derivatives in white peony root by UHPLC–MS–MS

  2012cites this paper
• Identification of ages and determination of paeoniflorin in roots of Paeonia lactiflora Pall. From four producing areas based on growth rings

  2012influential citation
• Total glucosides of paeony regulates JAK2/STAT3 activation and macrophage proliferation in diabetic rat kidneys.

  2012cites this paper
• Cardioprotective effect of total paeony glycosides against isoprenaline-induced myocardial ischemia in rats.

  2012cites this paper
• Renal protection of in vivo administration of tempol in streptozotocin-induced diabetic rats.

  2012cites this paper
• Peony glycosides reverse the effects of corticosterone on behavior and brain BDNF expression in rats.

  2012cites this paper
• Preparative purification of peoniflorin and albiflorin from peony rhizome using macroporous resin and medium-pressure liquid chromatography.

  2012cites this paper
• FK506 ameliorates renal injury in early experimental diabetic rats induced by streptozotocin.

  2011cites this paper
• Protective effects of total glucosides of paeony and the underlying mechanisms in carbon tetrachloride-induced experimental liver injury

  2011cites this paper
• Protective effects of peoniflorin against hydrogen peroxide-induced oxidative stress in human umbilical vein endothelial cells.

  2011cites this paper
• Long-term treatment with peony glycosides reverses chronic unpredictable mild stress-induced depressive-like behavior via increasing expression of neurotrophins in rat brain.

  2010cites this paper
• otal glucosides of Paeonia lactiflora Pall inhibit vascular endothelial growth actor-induced angiogenesis

  2010influential citation
• Total glucosides of Paeonia lactiflora Pall inhibit vascular endothelial growth factor-induced angiogenesis.

  2010cites this paper
• Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (Pro)renin receptor expression.

  2009cites this paper