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The concentration of serum zinc in celiac patients compared to healthy subjects in Tehran

Fariba Fathi,F. Ektefa,M. Tafazzoli,K. Rostami,M. R. Nejad,M. Fathi,M. Rezaei-Tavirani,Afsaneh Arefi Oskouie,M. Zali

Published 2013 in Gastroenterology and hepatology from bed to bench

ABSTRACT

Aim This study evaluated serum levels of zinc in patient with CD compare to healthy subjects. Background Celiac disease (CD) is characterized by small intestinal malabsorption of nutrients as a consequence of ingestion of wheat gluten. Zinc is an essential trace element that it has vital biological functions. Patients and methods Sera of 30 celiac cases and 30 healthy normal cohorts as control group were obtained. Atomic absorption spectrophotometer was employed for estimating serum zinc level. Results Zinc concentrations in patients diagnosed with CD were significantly lower than healthy subjects (75.97±12 compared with 92.83±18, P-value < 0.0001). Conclusion The result of this study shows that serum zinc concentration is decreased in celiac patients compare to healthy controls. Serum zinc may thus be a marker of CD in adults presenting with gastrointestinal symptoms.

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