Purinergic receptors on insulin‐secreting cells

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Fundamental & Clinical Pharmacology

• Publication date

  1994-03-04

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1472-8206.1994.tb00788.xPMID 8020870
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1991cited by this paper
• Purines: Basic and Clinical Aspects

  1991cited by this paper
• Noradrenaline-ATP co-transmission in the sympathetic nervous system.

  1991cited by this paper
• Extracellular ATP causes Ca2(+)-dependent and -independent insulin secretion in RINm5F cells. Phospholipase C mediates Ca2+ mobilization but not Ca2+ influx and membrane depolarization.

  1991cited by this paper
• Investigation of the selectivity of α, β‐methylene ATP in inhibiting vascular responses of the rat in vivo and in vitro

  1990cited by this paper
• Cardiovascular purinoceptors.

  1990cited by this paper
• Investigation of the selectivity of alpha, beta-methylene ATP in inhibiting vascular responses of the rat in vivo and in vitro.

  1990cited by this paper
• Difference in the potentiating effect of adenosine triphosphate and alpha, beta-methylene ATP on the biphasic insulin response to glucose.

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• Effects of extracellular adenine nucleotides on the electrical, ionic and secretory events in mouse pancreatic β‐cells

  1989cited by this paper
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  1989cited by this paper
• Difference in the potentiating effect of adenosine triphosphate and α,β‐methylene ATP on the biphasic insulin response to glucose

  1989cited by this paper
• Membrane and intracellular effects of adenosine in mouse pancreatic beta-cells.

  1989cited by this paper
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• Selective activation of Ca2+ influx by extracellular ATP in a pancreatic beta-cell line (HIT).

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• [Study of stereoisomers of N6-phenylisopropyladenosine on the secretion of pancreatic glucagon].

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• Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells

  1984cited by this paper
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  1983cited by this paper
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  1982cited by this paper
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• Metabolic signals produced by purine ribonucleosides stimulate proinsulin biosynthesis and insulin secretion.

  1978cited by this paper
• [Effect of strychnine, hydrastine and apamin on synaptic transmission in smooth muscle cells].

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• [Adenosine triphosphate (ATP) and insulin secretion: effect of different concentrations and effect of temperature].

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• [Adenosine triphosphate (ATP) and glucose. Action on insulin and glucagon secretion].

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• Purinergic receptors.

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