Crystal structure of metagenome-derived LC11-RNase H1 in complex with RNA/DNA hybrid.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Journal of Structural Biology

• Publication date

  2013-05-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.jsb.2013.02.018PMID 23500886
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• RNase H2-initiated ribonucleotide excision repair.

  2012cited by this paper
• Activity, stability, and structure of metagenome‐derived LC11‐RNase H1, a homolog of Sulfolobus tokodaii RNase H1

  2012cited by this paper
• RNase H and Postreplication Repair Protect Cells from Ribonucleotides Incorporated in DNA

  2012cited by this paper
• Faculty Opinions recommendation of Crystal structures of RNase H2 in complex with nucleic acid reveal the mechanism of RNA-DNA junction recognition and cleavage.

  2011cited by this paper
• HIV-1 RT-associated RNase H function inhibitors: Recent advances in drug development.

  2010cited by this paper
• Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage

  2010cited by this paper
• Cloning of the RNase H genes from a metagenomic DNA library: identification of a new type 1 RNase H without a typical active‐site motif

  2010cited by this paper
• The N‐terminal hybrid binding domain of RNase HI from Thermotoga maritima is important for substrate binding and Mg2+‐dependent activity

  2010cited by this paper
• Ribonuclease H: the enzymes in eukaryotes

  2009cited by this paper
• Ribonuclease H: molecular diversities, substrate binding domains, and catalytic mechanism of the prokaryotic enzymes

  2009cited by this paper
• Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

  2008cited by this paper
• Specific recognition of RNA/DNA hybrid and enhancement of human RNase H1 activity by HBD

  2008cited by this paper
• Crystal structure of type 1 ribonuclease H from hyperthermophilic archaeon Sulfolobus tokodaii: role of arginine 118 and C-terminal anchoring.

  2007cited by this paper
• Structure of human RNase H1 complexed with an RNA/DNA hybrid: insight into HIV reverse transcription.

  2007cited by this paper
• Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection

  2006cited by this paper
• Stepwise analyses of metal ions in RNase H catalysis from substrate destabilization to product release

  2006cited by this paper
• Making and breaking nucleic acids: two-Mg2+-ion catalysis and substrate specificity.

  2006cited by this paper
• Crystallization and preliminary crystallographic analysis of type 1 RNase H from the hyperthermophilic archaeon Sulfolobus tokodaii 7.

  2006cited by this paper
• Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis.

  2005cited by this paper
• Coot: model-building tools for molecular graphics.

  2004cited by this paper
• Cleavage of double-stranded RNA by RNase HI from a thermoacidophilic archaeon, Sulfolobus tokodaii 7.

  2004cited by this paper
• Human RNase H1 Uses One Tryptophan and Two Lysines to Position the Enzyme at the 3′-DNA/5′-RNA Terminus of the Heteroduplex Substrate*

  2003cited by this paper
• Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice.

  2003cited by this paper
• Dispensability of glutamic acid 48 and aspartic acid 134 for Mn2+-dependent activity of Escherichia coli ribonuclease HI.

  2003cited by this paper
• Cleavage of a DNA–RNA–DNA/DNA chimeric substrate containing a single ribonucleotide at the DNA–RNA junction with prokaryotic RNases HII

  2002cited by this paper
• An approach to multi-copy search in molecular replacement.

  2000cited by this paper
• Characterization of ribonuclease HII from Escherichia coli overproduced in a soluble form.

  2000cited by this paper
• The absence of ribonuclease H1 or H2 alters the sensitivity of Saccharomyces cerevisiae to hydroxyurea, caffeine and ethyl methanesulphonate: implications for roles of RNases H in DNA replication and repair

  2000cited by this paper
• Isolation of RNase H Genes That Are Essential for Growth of Bacillus subtilis 168

  1999cited by this paper
• Identification of the genes encoding Mn2+-dependent RNase HII and Mg2+-dependent RNase HIII from Bacillus subtilis: classification of RNases H into three families.

  1999cited by this paper
• Molecular diversities of RNases H.

  1999cited by this paper
• Saccharomyces cerevisiae RNase H(35) Functions in RNA Primer Removal during Lagging-Strand DNA Synthesis, Most Efficiently in Cooperation with Rad27 Nuclease

  1999cited by this paper
• [20] Processing of X-ray diffraction data collected in oscillation mode.

  1997cited by this paper
• Processing of X-ray diffraction data collected in oscillation mode.

  1997cited by this paper
• Kinetic and Stoichiometric Analysis for the Binding of Escherichia coli Ribonuclease HI to RNA-DNA Hybrids Using Surface Plasmon Resonance*

  1997cited by this paper
• Refinement of macromolecular structures by the maximum-likelihood method.

  1997cited by this paper
• Role of histidine 124 in the catalytic function of ribonuclease HI from Escherichia coli.

  1993cited by this paper
• Identification of the amino acid residues involved in an active site of Escherichia coli ribonuclease H by site-directed mutagenesis.

  1990cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper

• RNases H: Structure and mechanism.

  2019cites this paper
• Packing energetics determine the folding routes of the RNase-H proteins.

  2017cites this paper
• An Analytical and Computational Infrared Spectroscopic Review of Vibrational Modes in Nucleic Acids

  2016cites this paper
• Structural and biochemical characterization of a metagenome‐derived esterase with a long N‐terminal extension

  2015cites this paper
• Structure and stability of metagenome-derived glycoside hydrolase family 12 cellulase (LC-CelA) a homolog of Cel12A from Rhodothermus marinus

  2014cites this paper
• Trinucleotide expansion in disease: why is there a length threshold?

  2014cites this paper
• Structural basis for salt-dependent folding of ribonuclease H1 from halophilic archaeon Halobacterium sp. NRC-1.

  2014influential citation
• Role of N‐terminal extension of Bacillus stearothermophilus RNase H2 and C‐terminal extension of Thermotoga maritima RNase H2

  2013cites this paper