Teratological research using in vitro systems. V. Nonmammalian model systems.

T. Collins

Published 1987 in Environmental Health Perspectives

ABSTRACT

In this review of alternative tests to whole-animal rodent studies, the use of sub-mammalian and sub-vertebrate systems is investigated. The history, methodology, known limitations, end points, dose response, and requirements of virus, hydra, planarian, cricket, fish, amphibia, Drosophila, and chicken embryo systems are discussed.

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