Lack of BRAF-V600E Mutation in Papillary Tumor of the Pineal Region.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Neurosurgery

• Publication date

  2015-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1227/NEU.0000000000000877PMID 26125673
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Papillary tumor of the pineal region

  2017influential reference
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  2015cited by this paper
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  2014cited by this paper
• The clinical development of MEK inhibitors

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  2014influential reference
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  2014cited by this paper
• MEK in cancer and cancer therapy.

  2014cited by this paper
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  2014cited by this paper
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  2011cited by this paper
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