Effects of light-activated diazido-PtIV complexes on cancer cells in vitro

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences

• Publication date

  2013-07-28

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1098/rsta.2012.0118PMID 23776289
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Multi-photon excitation in uncaging the small molecule bioregulator nitric oxide

  2013cited by this paper
• Therapeutic Discovery Trans,trans,trans-[Pt(N3)2(OH)2(py)(NH3)]: A Light-Activated Antitumor Platinum Complex That Kills Human Cancer Cells by an Apoptosis-Independent Mechanism

  2012influential reference
• The unique role of nanoparticles in nanomedicine : imaging , drug delivery and therapy

  2012cited by this paper
• The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy.

  2012cited by this paper
• Molecules and membranes: Emerging details shed light on mammalian autophagy

  2012cited by this paper
• Interactions of DNA with a new platinum(IV) azide dipyridine complex activated by UVA and visible light: relationship to toxicity in tumor cells.

  2012influential reference
• It's time to eat yourself healthy: On signals controlling autophagy

  2012cited by this paper
• Trans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: A Light-Activated Antitumor Platinum Complex That Kills Human Cancer Cells by an Apoptosis-Independent Mechanism

  2012cited by this paper
• Ground and excited state properties of photoactive platinum(IV) diazido complexes: theoretical considerations.

  2011cited by this paper
• Studies on the photoactivation of two cytotoxic trans,trans,trans-diazidodiaminodihydroxo-Pt(IV) complexes.

  2011influential reference
• Influence of pyridine versus piperidine ligands on the chemical, DNA binding and cytotoxic properties of light activated trans,trans,trans-[Pt(N3)2(OH)2(NH3)(L)].

  2011influential reference
• Photoreaction pathways for the anticancer complex trans,trans,trans-[Pt(N3)2(OH)2(NH3)2].

  2011cited by this paper
• Antibody-drug conjugates: linking cytotoxic payloads to monoclonal antibodies.

  2010cited by this paper
• A potent trans-diimine platinum anticancer complex photoactivated by visible light.

  2010influential reference
• Photocytotoxic trans-diam(m)ine platinum(IV) diazido complexes more potent than their cis isomers.

  2010influential reference
• Decomposition pathways for the photoactivated anticancer complex cis,trans,cis-[Pt(N3)2(OH)2(NH3)2]: insights from DFT calculations.

  2009cited by this paper
• Photoactive trans ammine/amine diazido platinum(IV) complexes

  2009cited by this paper
• Characterization of chemosensitivity and resistance of human cancer cell lines to platinum(II) versus platinum(IV) anticancer agents

  2009cited by this paper
• Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes

  2009cited by this paper
• Photoactivated chemotherapy (PACT): the potential of excited-state d-block metals in medicine.

  2009cited by this paper
• Discovery and Development of Folic‐Acid‐Based Receptor Targeting for Imaging and Therapy of Cancer and Inflammatory Diseases

  2008cited by this paper
• Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

  2008cited by this paper
• Discovery and development of folic-acid-based receptor targeting for imaging and therapy of cancer and inflammatory diseases.

  2008cited by this paper
• Unprecedented carbon-carbon bond formation induced by photoactivation of a platinum(IV)-diazido complex.

  2008influential reference
• Photoactivatable platinum complexes.

  2007cited by this paper
• How to Interpret LC3 Immunoblotting

  2007cited by this paper
• A potent cytotoxic photoactivated platinum complex

  2007influential reference
• Biochemical mechanisms of cisplatin cytotoxicity.

  2007influential reference
• Drug metabolism: Crystals clarify metabolism

  2006influential reference
• A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin.

  2006influential reference
• Light-activated destruction of cancer cell nuclei by platinum diazide complexes.

  2006cited by this paper
• Correlations between the activities of 19 anti-tumor agents and the intracellular glutathione concentrations in a panel of 14 human cancer cell lines: comparisons with the National Cancer Institute data

  2006cited by this paper
• Polymeric anticancer drugs with pH-controlled activation.

  2004cited by this paper
• Nucleotide cross-linking induced by photoreactions of platinum(IV)-azide complexes.

  2003influential reference
• Formation of platinated GG cross-links on DNA by photoactivation of a platinum(IV) azide complex

  2003cited by this paper
• Nucleotide Platination Induced by Visible Light.

  1999cited by this paper
• synthesis and X-ray crystal structure

  1999cited by this paper
• Gene-directed enzyme prodrug therapy.

  1998cited by this paper
• ELECTRON-TRANSFER-DRIVEN TRANS-LIGAND LABILIZATION : A NOVEL ACTIVATION MECHANISM FOR PT(IV) ANTICANCER COMPLEXES

  1998influential reference
• Photolysis of an iodoplatinum(IV) diamine complex to cytotoxic species by visible light.

  1996influential reference
• Synthesis and X-ray crystal structure of trans,cis-[Pt(OAc)2I2(en)]: a novel type of cisplatin analog that can be photolyzed by visible light to DNA-binding and cytotoxic species in vitro.

  1996cited by this paper
• A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V.

  1995cited by this paper
• Apoptosis, oncosis, and necrosis. An overview of cell death.

  1995cited by this paper
• Antibody-Directed Enzyme Prodrug Therapy

  1994cited by this paper
• New platinum antitumor complexes.

  1993cited by this paper
• Flow cytometric studies of oxidative product formation by neutrophils: a graded response to membrane stimulation.

  1983cited by this paper
• Photochemical Four‐Electron Redox Reaction of Hexaazidoplatinate(IV)

  1983cited by this paper
• Photochemical Reductive cis‐Elimination in cis‐Diazidobis(triphenylphosphane)platinum(II) Evidence of the Formation of Bis(triphenylphosphane)platinum(0) and Hexaazabenzene

  1980cited by this paper
• Photochemical Reductive trans‐Elimination from trans‐Diazidotetracyanoplatinate(IV)

  1978influential reference

• Ultrafast photochemical processes in the complex trans,trans,trans-[Ptiv(py)2(N3)2(OH)2]

  2024cites this paper
• Chain photosolvation of trans,trans,trans-[PtIV(py)2(N3)2(OH)2] complex prospective as a light-activated antitumor agent

  2023cites this paper
• Development of Photoremovable Linkers as a Novel Strategy to Improve the Pharmacokinetics of Drug Conjugates and Their Potential Application in Antibody–Drug Conjugates for Cancer Therapy

  2022cites this paper
• The Role of Triplet States in the Photodissociation of a Platinum Azide Complex by a Density Matrix Renormalization Group Method

  2021cites this paper
• Photoactive metallodrugs

  2021cites this paper
• Simplified State Interaction for Matrix Product State Wave Functions

  2021cites this paper
• Photofunctional transition metal complexes as cellular probes, bioimaging reagents and phototherapeutics

  2021cites this paper
• Single-Cell Chemistry of Photoactivatable Platinum Anticancer Complexes

  2021cites this paper
• Three Reactions, One Catalyst: A Multi‐Purpose Platinum(IV) Complex and its Silica‐Supported Homologue for Environmentally Friendly Processes

  2020cites this paper
• Axial functionalisation of photoactive diazido platinum(iv) anticancer complexes

  2020cites this paper
• Diazido platinum(iv) complexes for photoactivated anticancer chemotherapy

  2019cites this paper
• New Designs for Phototherapeutic Transition Metal Complexes

  2019cites this paper
• Platinum alkynyl complexes: Cellular uptake, inhibition of thioredoxin reductase and toxicity in zebrafish embryos

  2019cites this paper
• The Evaluation of the Effects of N-Acetylcysteine on Cisplatin-Induced Alterations in Exploratory Activity in Elevated Plus Maze Test in Rats

  2019cites this paper
• Selective Activation of Transition-Metal Complexes in Medicine

  2018cites this paper
• A Photoactive Platinum(IV) Anticancer Complex Inhibits Thioredoxin-Thioredoxin Reductase System Activity by Induced Oxidization of the Protein.

  2018cites this paper
• Hydrogen-Bonded Organic–Inorganic Hybrid Based on Hexachloroplatinate and Nitrogen Heterocyclic Cations: Their Synthesis, Characterization, Crystal Structures, and Antitumor Activities In Vitro

  2018cites this paper
• Current Developments in Pt(IV) Prodrugs Conjugated with Bioactive Ligands

  2018cites this paper
• Current Status for Oral Platinum (IV) Anticancer Drug Development

  2018cites this paper
• Biological applications of Ru(II) polypyridyl complexes

  2018cites this paper
• Prediction of 195Pt NMR of photoactivable diazido‐ and azine‐Pt(IV) anticancer agents by DFT computational protocols

  2017cites this paper
• Fluorescent light induces neurodegeneration in the rodent nigrostriatal system but near infrared LED light does not.

  2017cites this paper
• Primary photochemical processes for Pt(iv) diazido complexes prospective in photodynamic therapy of tumors.

  2017cites this paper
• Platinum nanoparticles induce damage to DNA and inhibit DNA replication

  2017cites this paper
• Photochemistry of cis,trans-[Pt(en)(I)2(OH)2] complex in aqueous solutions

  2017cites this paper
• Correction: Platinum complexes as light promoted anticancer agents: a redefined strategy for controlled activation.

  2016cites this paper
• New trends in platinum and palladium complexes as antineoplastic agents

  2016cites this paper
• Platinum complexes as light promoted anticancer agents: a redefined strategy for controlled activation.

  2016cites this paper
• Cobalt(III) Chaperone Complexes of Curcumin: Photoreduction, Cellular Accumulation and Light-Selective Toxicity towards Tumour Cells.

  2015cites this paper
• Binding of a potential anti-hepatoma drug cis,cis,trans-[Pt(NH3)2Cl2(O2CCH2CH2COOH)-(OCONHC16H33)] with serum albumin – thermodynamic and conformational investigations

  2015cites this paper
• Platinum Anticancer Drugs and Photochemotherapeutic Agents: Recent Advances and Future Developments

  2014cites this paper
• Visible-light-induced annihilation of tumor cells with platinum-porphyrin conjugates.

  2014cites this paper
• Nanoscale drug delivery platforms overcome platinum-based resistance in cancer cells due to abnormal membrane protein trafficking.

  2013cites this paper