Structure of the FHA1 domain of yeast Rad53 and identification of binding sites for both FHA1 and its target protein Rad9.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Journal of Molecular Biology

• Publication date

  2000-12-15

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1006/JMBI.2000.4291PMID 11124038
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization of heparin binding of human extracellular superoxide dismutase.

  2000cited by this paper
• II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.

  2000cited by this paper
• FHA domain boundaries of the Dun1p and Rad53p cell cycle checkpoint kinases

  2000cited by this paper
• The FHA domain is a modular phosphopeptide recognition motif.

  1999cited by this paper
• Protein backbone angle restraints from searching a database for chemical shift and sequence homology

  1999cited by this paper
• Kinase interaction domain of kinase-associated protein phosphatase, a phosphoprotein-binding domain.

  1999cited by this paper
• Structure and function of a new phosphopeptide-binding domain containing the FHA2 of Rad53.

  1999cited by this paper
• Determination of substrate specificity for peptide deformylase through the screening of a combinatorial peptide library.

  1999cited by this paper
• Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint.

  1998cited by this paper
• Combinatorial epitope search: Pitfalls of library design

  1997cited by this paper
• Use of surface plasmon resonance to probe the equilibrium and dynamic aspects of interactions between biological macromolecules.

  1997cited by this paper
• MOLMOL: a program for display and analysis of macromolecular structures.

  1996cited by this paper
• GENERATION AND SCREENING OF COMBINATORIAL PEPTIDE LIBRARIES DESIGNED FOR RAPID SEQUENCING BY MASS SPECTROMETRY

  1995cited by this paper
• Surface plasmon resonance detection and multispot sensing for direct monitoring of interactions involving low-molecular-weight analytes and for determination of low affinities.

  1995cited by this paper
• The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors.

  1995cited by this paper
• Gradient-Enhanced Triple-Resonance Three-Dimensional NMR Experiments with Improved Sensitivity

  1994cited by this paper
• Principles of Peptide Synthesis

  1993influential reference
• PROCHECK: a program to check the stereochemical quality of protein structures

  1993cited by this paper
• Protein structure comparison by alignment of distance matrices.

  1993cited by this paper
• A new type of synthetic peptide library for identifying ligand-binding activity

  1992cited by this paper
• Improved 3D triple-resonance NMR techniques applied to a 31 kDa protein

  1992cited by this paper
• Correlating Backbone Amide and Side-Chain Resonances in Larger Proteins By Multiple Relayed Triple Resonance NMR

  1992cited by this paper
• A new type of synthetic peptide library for identifying ligand-binding activity

  1992cited by this paper
• A novel approach for sequential assignment of proton, carbon-13, and nitrogen-15 spectra of larger proteins: heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin

  1990cited by this paper
• A novel approach for sequential assignment of 1H, 13C, and 15N spectra of proteins: heteronuclear triple-resonance three-dimensional NMR spectroscopy. Application to calmodulin.

  1990cited by this paper
• Determination of three‐dimensional structures of proteins from interproton distance data by dynamical simulated annealing from a random array of atoms Circumventing problems associated with folding

  1988influential reference
• Pseudo-structures for the 20 common amino acids for use in studies of protein conformations by measurements of intramolecular proton-proton distance constraints with nuclear magnetic resonance.

  1983cited by this paper

• Sae2 integrates CDK and checkpoint phosphorylation to coordinate MRX cleavage with checkpoint attenuation

  2025cites this paper
• Interaction between SARS-CoV PBM and Cellular PDZ Domains Leading to Virus Virulence

  2024cites this paper
• Genetically Engineered Live-Attenuated Middle East Respiratory Syndrome Coronavirus Viruses Confer Full Protection against Lethal Infection

  2021cites this paper
• Generating and Characterizing Phosphospecific Affinity Reagents Using the Forkhead-Associated 1 Domain

  2018cites this paper
• Structural insights into the recognition of phosphorylated Hop1 by Mek1.

  2018influential citation
• S-phase checkpoint activity and function throughout the cell cycle

  2017cites this paper
• Mycobacterium tuberculosis universal stress protein Rv2623 interacts with the putative ATP binding cassette (ABC) transporter Rv1747 to regulate mycobacterial growth

  2017cites this paper
• Phospho-Priming Confers Functionally Relevant Specificities for Rad53 Kinase Autophosphorylation.

  2017cites this paper
• A comparison of phosphospecific affinity reagents reveals the utility of recombinant Forkhead-associated domains in recognizing phosphothreonine-containing peptides.

  2016cites this paper
• Visualization of Compartmentalized Kinase Activity Dynamics Using Adaptable BimKARs.

  2015cites this paper
• Uncovering the Mechanism of Forkhead-Associated Domain-Mediated TIFA Oligomerization That Plays a Central Role in Immune Responses.

  2015cites this paper
• Versatility in phospho-dependent molecular recognition of the XRCC1 and XRCC4 DNA-damage scaffolds by aprataxin-family FHA domains

  2015cites this paper
• Generating Recombinant Affinity Reagents by Phage- and Ribosome-Display

  2014cites this paper
• Achieving Peptide Binding Specificity and Promiscuity by Loops: Case of the Forkhead-Associated Domain

  2014cites this paper
• Transcription factor for gene function analysis in maize.

  2014influential citation
• Investigating the role of CK2 in the DNA damage response

  2014cites this paper
• Use of Quantitative Mass Spectrometric Analysis to Elucidate the Mechanisms of Phospho-priming and Auto-activation of the Checkpoint Kinase Rad53 in Vivo

  2013cites this paper
• Functional analyses of pSer and pThr binding domains

  2013cites this paper
• The Molecular Basis of Substrate Recognition by the Family of Pellino E3 Ubiquitin Ligases

  2013cites this paper
• Directed evolution of the forkhead-associated domain to generate anti-phosphospecific reagents by phage display.

  2012cites this paper
• 14-3-3 Proteins , FHA Domains and BRCT Domains in the DNA Damage Response Citation

  2012cites this paper
• Surprising complexity of the Asf1 histone chaperone-Rad53 kinase interaction

  2012influential citation
• Mechanism of PhosphoThreonine/Serine Recognition and Specificity for Modular Domains from All-atom Molecular Dynamics

  2011cites this paper
• Cell cycle-dependent phosphorylation of Rad53 kinase by Cdc5 and Cdc28 modulates checkpoint adaptation

  2010cites this paper
• A Strategy for Interaction Site Prediction between Phospho-binding Modules and their Partners Identified from Proteomic Data*

  2010cites this paper
• Recognition of Phospho-Serine/Threonine Phosphorylated Proteins by Phospho-Serine/Threonine-Binding Domains

  2010cites this paper
• alpha-Helical burst on the folding pathway of FHA domains from Rad53 and Ki67.

  2010cites this paper
• The Roles of Conserved Dbf4 Motifs in DNA Replication and Checkpoint Responses in Saccharomyces cerevisiae

  2010cites this paper
• 14-3-3 proteins, FHA domains and BRCT domains in the DNA damage response.

  2009cites this paper
• A Correction to the Review Titled: "Structure and Function of the Phosphothreonine-Specific FHA Domain" by A. Mahajan, C. Yuan, H. Lee, E. S.-W. Chen, P.-Y. Wu, M.-D. Tsai

  2009cites this paper
• Mechanistic insights into phosphoprotein-binding FHA domains.

  2008cites this paper
• Location-specific functions of the two forkhead-associated domains in Rad53 checkpoint kinase signaling.

  2008cites this paper
• Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade.

  2008influential citation
• Polynucleotide kinase as a potential target for enhancing cytotoxicity by ionizing radiation and topoisomerase I inhibitors.

  2008cites this paper
• Pellino proteins contain a cryptic FHA domain that mediates interaction with phosphorylated IRAK1.

  2008influential citation
• The NMR structure of the NIPP1 FHA domain

  2008cites this paper
• Structure and Function of the Phosphothreonine-Specific FHA Domain

  2008influential citation
• Regulation of cell wall synthesis and growth.

  2007cites this paper
• Phosphorylation events surrounding the DNA damage response in "Saccharomyces cerevisiae"

  2007cites this paper
• Phosphoprotein and phosphopeptide interactions with the FHA domain from Arabidopsis kinase-associated protein phosphatase.

  2007cites this paper
• Regulation of Histone Covalent Modifications During Yeast Apoptosis

  2007cites this paper
• Mechanisms of Checkpoint Kinase Rad53 Inactivation after a Double-Strand Break in Saccharomyces cerevisiae

  2007cites this paper
• Kinase-interacting FHA domain of kinase associated protein phosphatase : phosphopeptide interactions and NMR-detected dynamics

  2007cites this paper
• Interactions of Forkhead-Associated Domain, FHA1 of Saccharomyces Cerevisiae Rad53 kinase with itself and the biological partners, Mdt1 and Rad9

  2006cites this paper
• Functional studies of serine/threonine protein kinase signalling in Mycobacterium tuberculosis

  2006cites this paper
• DAWDLE, a Forkhead-Associated Domain Gene, Regulates Multiple Aspects of Plant Development1[W]

  2006cites this paper
• Nonhomologous end joining in yeast.

  2005cites this paper
• Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains.

  2005cites this paper
• SQ/TQ cluster domains: concentrated ATM/ATR kinase phosphorylation site regions in DNA‐damage‐response proteins

  2005cites this paper
• PhosphoThr peptide binding globally rigidifies much of the FHA domain from Arabidopsis receptor kinase-associated protein phosphatase.

  2005cites this paper
• Survey of the year 2003 commercial optical biosensor literature

  2005cites this paper
• FHA domain-ligand interactions: importance of integrating chemical and biological approaches.

  2005cites this paper
• Isolation and functional analysis of a chk2 homologue from Entamoeba histolytica.

  2005cites this paper
• Alternative mode of binding to phosphotyrosyl peptides by Src homology-2 domains.

  2005cites this paper
• Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67

  2005cites this paper
• The Chk2 protein kinase.

  2004cites this paper
• The ligand specificity of yeast Rad53 FHA domains at the +3 position is determined by nonconserved residues.

  2004cites this paper
• Two FHA domains on an ABC transporter, Rv1747, mediate its phosphorylation by PknF, a Ser/Thr protein kinase from Mycobacterium tuberculosis.

  2004cites this paper
• Structure of human Ki67 FHA domain and its binding to a phosphoprotein fragment from hNIFK reveal unique recognition sites and new views to the structural basis of FHA domain functions.

  2004cites this paper
• Rad53 Kinase Activation-independent Replication Checkpoint Function of the N-terminal Forkhead-associated (FHA1) Domain*

  2004cites this paper
• Cds1 Phosphorylation by Rad3-Rad26 Kinase Is Mediated by Forkhead-associated Domain Interaction with Mrc1*

  2004cites this paper
• Controlling integration specificity of a yeast retrotransposon

  2003cites this paper
• Structure of KI67 FHA domain and its binding to HNIFK

  2003cites this paper
• FHA Domain-Mediated DNA Checkpoint Regulation of Rad53

  2003cites this paper
• Identification of potential binding sites for the FHA domain of human Chk2 by in vitro binding studies.

  2003cites this paper
• DNA DAMAGE SENSORS IN THE CHECKPOINT RESPONSE

  2003cites this paper
• Analysis of Rad9 Functions; Roles in the Checkpoint Response, DNA Damage Processing, and Prevention of Genomic Instability

  2003cites this paper
• PP2C phosphatases Ptc2 and Ptc3 are required for DNA checkpoint inactivation after a double-strand break.

  2003cites this paper
• Diverse but Overlapping Functions of the Two Forkhead-associated (FHA) Domains in Rad53 Checkpoint Kinase Activation*

  2003cites this paper
• NMR structure of the forkhead-associated domain from the Arabidopsis receptor kinase-associated protein phosphatase

  2003cites this paper
• CHAPTER 85 – Recognition of Phospho-Serine/Threonine Phosphorylated Proteins

  2003cites this paper
• Checkpoint Kinase 2 (Chk2) Monomers or Dimers Phosphorylate Cdc25C after DNA Damage Regardless of Threonine 68 Phosphorylation*

  2002cites this paper
• The FHA domain

  2002cites this paper
• Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2.

  2002cites this paper
• Chk2 Activation and Phosphorylation-Dependent Oligomerization

  2002cites this paper
• Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint.

  2002cites this paper
• Posttranscriptional Regulation of the RAD5 DNA Repair Gene by the Dun1 Kinase and the Pan2-Pan3 Poly(A)-Nuclease Complex Contributes to Survival of Replication Blocks*

  2002cites this paper
• Forkhead-associated Domains of the Tobacco NtFHA1 Transcription Activator and the Yeast Fhl1 Forkhead Transcription Factor Are Functionally Conserved*

  2002cites this paper
• Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.

  2002cites this paper
• An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing

  2002cites this paper
• PhosphoSerine/Threonine Binding Minireview Domains: You Can't pSERious?

  2001cites this paper
• Development of photoreversible covalent inhibitors for protein tyrosine phosphatases.

  2001cites this paper
• Solution structures of two FHA1-phosphothreonine peptide complexes provide insight into the structural basis of the ligand specificity of FHA1 from yeast Rad53.

  2001cites this paper
• Current awareness on yeast.

  2001cites this paper
• Rapid sequencing of library-derived peptides by partial edman degradation and mass spectrometry.

  2001cites this paper
• A Novel Nucleolar Protein, NIFK, Interacts with the Forkhead Associated Domain of Ki-67 Antigen in Mitosis*

  2001cites this paper
• Role of the N-terminal Forkhead-associated Domain in the Cell Cycle Checkpoint Function of the Rad53 Kinase* 210

  2001cites this paper
• Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.

  2001cites this paper
• Survey of the year 2000 commercial optical biosensor literature.

  2001cites this paper
• PhosphoSerine/threonine binding domains: you can't pSERious?

  2001cites this paper