Modulation of host defense by the neuropeptide alpha-MSH.

alpha-melanocyte stimulating hormone (alpha-MSH), a peptide that occurs within the brain, the circulation, and other body sites, is a potent antipyretic agent when given centrally or peripherally. The peptide likewise inhibits inflammation and aspects of the acute-phase response. The combined evidence suggests that alpha-MSH molecules act as natural modulators of host reactions by antagonizing the central and peripheral actions of cytokines.

• Publication year

  1990

• Venue

  The Yale Journal of Biology and Medicine

• Publication date

  1990-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 2205057PMCID 2589306
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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