Meis1 coordinates a network of genes implicated in eye development and microphthalmia

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Development

• Publication date

  2015-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1242/dev.122176PMID 26253404
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Meis2 is a Pax6 co-factor in neurogenesis and dopaminergic periglomerular fate specification in the adult olfactory bulb

  2014cited by this paper
• The genetic architecture of microphthalmia, anophthalmia and coloboma.

  2014cited by this paper
• Diffusible signals and epigenetic timing cooperate in late proximo-distal limb patterning

  2014cited by this paper
• TALE transcription factors during early development of the vertebrate brain and eye

  2014cited by this paper
• Longitudinal fundus and retinal studies with SD-OCT: a comparison of five mouse inbred strains

  2013cited by this paper
• Lens density tracking in mice by Scheimpflug imaging

  2013cited by this paper
• The regulation of Hox gene expression during animal development

  2013cited by this paper
• Biochemistry of the tale transcription factors PREP, MEIS, and PBX in vertebrates

  2013influential reference
• The logic of gene regulatory networks in early vertebrate forebrain patterning.

  2013influential reference
• Characterizing visual performance in mice: an objective and automated system based on the optokinetic reflex.

  2013cited by this paper
• The impairment of HCCS leads to MLS syndrome by activating a non-canonical cell death pathway in the brain and eyes

  2013cited by this paper
• Meis1 regulates Foxn4 expression during retinal progenitor cell differentiation

  2013cited by this paper
• Analysis of the DNA-binding profile and function of TALE homeoproteins reveals their specialization and specific interactions with Hox genes/proteins.

  2013cited by this paper
• Genetic and physical interaction of Meis2, Pax3 and Pax7 during dorsal midbrain development

  2012cited by this paper
• Identification and Analysis of Conserved cis-Regulatory Regions of the MEIS1 Gene

  2012cited by this paper
• A map of the cis-regulatory sequences in the mouse genome

  2012cited by this paper
• An Integrated Encyclopedia of DNA Elements in the Human Genome

  2012cited by this paper
• Eye development genes and known syndromes.

  2011cited by this paper
• Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification

  2011cited by this paper
• BMP4 loss-of-function mutations in developmental eye disorders including SHORT syndrome

  2011cited by this paper
• The genetics of anophthalmia and microphthalmia

  2011cited by this paper
• RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

  2011cited by this paper
• Cofactor binding evokes latent differences in DNA binding specificity between Hox proteins.

  2011cited by this paper
• Mutations in the SPARC-related modular calcium-binding protein 1 gene, SMOC1, cause waardenburg anophthalmia syndrome.

  2011cited by this paper
• Pbx homeodomain proteins: TALEnted regulators of limb patterning and outgrowth

  2011cited by this paper
• SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis

  2011cited by this paper
• SMOC1 is essential for ocular and limb development in humans and mice.

  2011cited by this paper
• FOXE3 plays a significant role in autosomal recessive microphthalmia

  2010cited by this paper
• Eye morphogenesis and patterning of the optic vesicle.

  2010influential reference
• miR-204 is required for lens and retinal development via Meis2 targeting

  2010cited by this paper
• GREAT improves functional interpretation of cis-regulatory regions

  2010cited by this paper
• Meis1 specifies positional information in the retina and tectum to organize the zebrafish visual system

  2010cited by this paper
• SOX1 links the function of neural patterning and Notch signalling in the ventral spinal cord during the neuron-glial fate switch.

  2009cited by this paper
• GADEM: A Genetic Algorithm Guided Formation of Spaced Dyads Coupled with an EM Algorithm for Motif Discovery

  2009cited by this paper
• Ectopic Meis1 expression in the mouse limb bud alters P-D patterning in a Pbx1-independent manner.

  2009cited by this paper
• Mouse models of cataract

  2009cited by this paper
• edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

  2009cited by this paper
• Meis2 competes with the Groucho co-repressor Tle4 for binding to Otx2 and specifies tectal fate without induction of a secondary midbrain-hindbrain boundary organizer

  2009cited by this paper
• meis1 regulates cyclin D1 and c-myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye

  2008cited by this paper
• Pbx/Meis Deficiencies Demonstrate Multigenetic Origins of Congenital Heart Disease

  2008cited by this paper
• Identification of STRA6 and SKI sequence variants in patients with anophthalmia/microphthalmia

  2008influential reference
• Evidence for an evolutionary conserved role of homothorax/Meis1/2 during vertebrate retina development

  2008influential reference
• Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary dysplasia, lung hypoplasia, and mental retardation.

  2007influential reference
• The rise and fall of Hox gene clusters

  2007cited by this paper
• Variations of eye size parameters among different strains of mice

  2006cited by this paper
• Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property

  2006cited by this paper
• Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development.

  2006cited by this paper
• SOX2 is a dose-dependent regulator of retinal neural progenitor competence.

  2006cited by this paper
• Secreted inducers in vertebrate eye development: more functions for old morphogens.

  2006cited by this paper
• Proper patterning of the optic fissure requires the sequential activity of BMP7 and SHH

  2006cited by this paper
• Microphthalmia with linear skin defects (MLS) syndrome: Clinical, cytogenetic, and molecular characterization of 11 cases

  2005cited by this paper
• Proximodistal identity during vertebrate limb regeneration is regulated by Meis homeodomain proteins

  2005cited by this paper
• Heterozygous mutations of OTX2 cause severe ocular malformations.

  2005cited by this paper
• The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo.

  2005influential reference
• Differentiation of the vertebrate retina is coordinated by an FGF signaling center.

  2005cited by this paper
• Rapid quantification of adult and developing mouse spatial vision using a virtual optomotor system.

  2004cited by this paper
• Pathways regulating lens induction in the mouse.

  2004influential reference
• Hematopoietic, angiogenic and eye defects in Meis1 mutant animals

  2004influential reference
• Analysis of the developmental SIX6 homeobox gene in patients with anophthalmia/microphthalmia

  2004cited by this paper
• Eye development: a view from the retina pigmented epithelium

  2004cited by this paper
• Oculofaciocardiodental and Lenz microphthalmia syndromes result from distinct classes of mutations in BCOR

  2004cited by this paper
• Sox1 acts through multiple independent pathways to promote neurogenesis.

  2004cited by this paper
• Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis

  2004cited by this paper
• Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1

  2004cited by this paper
• Mutations in the human RAX homeobox gene in a patient with anophthalmia and sclerocornea.

  2003cited by this paper
• Novel mutation in sonic hedgehog in non‐syndromic colobomatous microphthalmia

  2003cited by this paper
• Mutations in SOX2 cause anophthalmia

  2003influential reference
• Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis.

  2002influential reference
• Combinatorial control of Drosophila eye development by eyeless, homothorax, and teashirt.

  2002cited by this paper
• Otx genes are required for tissue specification in the developing eye.

  2001cited by this paper
• Human microphthalmia associated with mutations in the retinal homeobox gene CHX10

  2000cited by this paper
• Spatial specification of mammalian eye territories by reciprocal transcriptional repression of Pax2 and Pax6.

  2000cited by this paper
• Dorsal-ventral patterning defects in the eye of BF-1-deficient mice associated with a restricted loss of shh expression.

  1999cited by this paper
• Conserved regulation of proximodistal limb axis development by Meis1/Hth

  1999cited by this paper
• Implication of OTX2 in Pigment Epithelium Determination and Neural Retina Differentiation

  1997cited by this paper
• Expression of winged helix genes, BF-1 and BF-2, define adjacent domains within the developing forebrain and retina.

  1994cited by this paper
• Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer.

  1994cited by this paper
• PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects

  1994cited by this paper
• Autopsy findings in a severely affected infant with a 2q terminal deletion.

  1993cited by this paper
• Current Opinion in Ophthalmology

  1992influential reference
• De novo inv(2)(p21q31) associated with isolated bilateral microphthalmia and cataracts.

  1991cited by this paper
• Developmental Biology

  1968cited by this paper

• Role of MNX1-mediated histone modifications and PBX gene family in MNX1-induced leukemogenesis

  2026cites this paper
• Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis

  2025cites this paper
• MEIS1: From functional versatility to post-transcriptional/translational regulation.

  2025cites this paper
• Persistent Transcriptome Alterations in Zebrafish Embryos After Discontinued Opioid Exposure

  2025cites this paper
• Overexpression of Meis factors in late-stage retinal progenitors yields complex effects on temporal patterning and neurogenesis

  2025cites this paper
• Generation of insulin-like growth factor 1 receptor-knockout pigs as a potential system for interspecies organogenesis

  2024cites this paper
• RLS-associated MEIS transcription factors control distinct processes in human neural stem cells

  2024influential citation
• Overexpression of Bmp4 induces microphthalmia by disrupting embryonic neural retina.

  2024cites this paper
• Optic cup morphogenesis across species and related inborn human eye defects

  2023cites this paper
• Signaling – transcription interactions in mouse retinal ganglion cells early axon pathfinding –a literature review

  2023cites this paper
• Meis1 plays roles in cortical development through regulation of cellular proliferative capacity in the embryonic cerebrum.

  2022cites this paper
• The TALE never ends: A comprehensive overview of the role of PBX1, a TALE transcription factor, in human developmental defects

  2022influential citation
• De novo PBX1 variant in a patient with glaucoma, kidney anomalies, and developmental delay: An expansion of the CAKUTHED phenotype

  2021cites this paper
• Single-cell analysis of early chick hypothalamic development reveals that hypothalamic cells are induced from prethalamic-like progenitors

  2021cites this paper
• Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors

  2021cites this paper
• Meis homeobox genes control progenitor competence in the retina

  2021influential citation
• Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea

  2021cites this paper
• Homeobox gene Meis1 modulates cardiovascular regeneration.

  2020cites this paper
• Inherited Eye Diseases with Retinal Manifestations through the Eyes of Homeobox Genes

  2020cites this paper
• Homeobox transcription factor Meis1 is crucial to Sertoli cell mediated regulation of male fertility

  2020cites this paper
• MEIS1 down-regulation by MYC mediates prostate cancer development through elevated HOXB13 expression and AR activity

  2019cites this paper
• Dental Epithelial Stem Cells Express the Developmental Regulator Meis1

  2019cites this paper
• Anephrogenic phenotype induced by SALL1 gene knockout in pigs

  2019cites this paper
• MEIS transcription factors in development and disease

  2019cites this paper
• RECAPITULATING DEVELOPMENTAL MECHANISMS FOR RETINAL REGENERATION.

  2019cites this paper
• Gene regulatory network reconstruction 3D chromosomal architecture reveals key transcription factors and DNA elements driving neural lineage commitment

  2019cites this paper
• Highly dynamic chromatin interactions drive neurogenesis through gene regulatory networks

  2018cites this paper
• Sox2 and Meis1 in tooth development and murine incisor renewal

  2018influential citation
• Differential Dopamine D1 and D3 Receptor Modulation and Expression in the Spinal Cord of Two Mouse Models of Restless Legs Syndrome

  2018cites this paper
• Evaluation of the role of Meis2 during inner ear formation and morphogenesis

  2018cites this paper
• Genetics of congenital eye malformations: insights from chick experimental embryology

  2018cites this paper
• A detailed characterization of congenital defects and mortality following moderate X-ray doses during neurulation.

  2018cites this paper
• Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma

  2018cites this paper
• Update on the Tuber Activation Pathway The Multiple Signals That Control Tuber Formation 1 [ OPEN ]

  2017cites this paper
• Meis1: effects on motor phenotypes and the sensorimotor system in mice

  2017cites this paper
• The Multiple Signals That Control Tuber Formation1[OPEN]

  2017cites this paper
• MEIS1 inhibits clear cell renal cell carcinoma cells proliferation and in vitro invasion or migration

  2017cites this paper
• Update on the Tuber Activation Pathway 2 3 The multiple signals that control tuber formation 4 5

  2017cites this paper
• Distinct morphologies of fusion and closure of the choroid fissure

  2017cites this paper
• Co-regulation of microRNAs and transcription factors in cardiomyocyte specific differentiation of murine embryonic stem cells: An aspect from transcriptome analysis.

  2017cites this paper
• Modeling Glaucoma: Retinal Ganglion Cells Generated from Induced Pluripotent Stem Cells of Patients with SIX6 Risk Allele Show Developmental Abnormalities

  2017cites this paper
• A tale of TALE, PREP1, PBX1, and MEIS1: Interconnections and competition in cancer.

  2017cites this paper
• The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6

  2016cites this paper