Functional NMDA receptors with atypical properties are expressed in podocytes.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  American Journal of Physiology - Cell Physiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/ajpcell.00268.2010PMID 20739624PMCID PMC3023196
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Functional NMDA receptors in rat erythrocytes.

  2010cited by this paper
• Redox signaling via lipid raft clustering in homocysteine-induced injury of podocytes.

  2010cited by this paper
• Early increase in extrasynaptic NMDA receptor signaling and expression contributes to phenotype onset in Huntington's disease mice.

  2010cited by this paper
• Activity‐dependent synaptic plasticity of NMDA receptors

  2010cited by this paper
• NMDA Receptors are Expressed in Lymphocytes Activated Both In Vitro and In Vivo

  2010cited by this paper
• Aspartate racemase, generating neuronal D-aspartate, regulates adult neurogenesis

  2010cited by this paper
• Coupling of the NMDA receptor to neuroprotective and neurodestructive events.

  2009cited by this paper
• Neurotransmitters Drive Combinatorial Multistate Postsynaptic Density Networks

  2009cited by this paper
• Podocyte glutamatergic signaling contributes to the function of the glomerular filtration barrier.

  2009influential reference
• Glutamate, excitotoxicity, and programmed cell death in Parkinson disease.

  2009cited by this paper
• N-methyl-D-aspartate receptors are expressed in rat parathyroid gland and regulate PTH secretion.

  2009cited by this paper
• Hydrogen sulfide ameliorates hyperhomocysteinemia-associated chronic renal failure.

  2009cited by this paper
• Renal NMDA receptors independently stimulate proximal reabsorption and glomerular filtration.

  2009influential reference
• Signaling in Regulation of Podocyte Phenotypes

  2009cited by this paper
• Nephrin binds to the COOH terminus of a large-conductance Ca2+-activated K+ channel isoform and regulates its expression on the cell surface.

  2008cited by this paper
• NMDA receptor blocker ameliorates ischemia-reperfusion-induced renal dysfunction in rat kidneys.

  2008influential reference
• Increased vulnerability of hippocampal neurons with age in culture: temporal association with increases in NMDA receptor current, NR2A subunit expression and recruitment of L-type calcium channels.

  2007cited by this paper
• Emerging cardiovascular risk factors that account for a significant portion of attributable mortality risk in chronic kidney disease.

  2007cited by this paper
• NMDA receptor function: subunit composition versus spatial distribution

  2006cited by this paper
• New targets for pharmacological intervention in the glutamatergic synapse.

  2006cited by this paper
• The role of N‐methyl‐D‐asparate receptors in neurogenesis

  2006cited by this paper
• Glia-derived D-serine controls NMDA receptor activity and synaptic memory.

  2006cited by this paper
• Glomerular podocytes contain neuron‐like functional synaptic vesicles

  2006influential reference
• Subunit arrangement and function in NMDA receptors

  2005cited by this paper
• TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function

  2005cited by this paper
• A Mutation in the TRPC6 Cation Channel Causes Familial Focal Segmental Glomerulosclerosis

  2005cited by this paper
• Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels.

  2005cited by this paper
• Association between serum homocysteine and markers of impaired kidney function in adults in the United States.

  2004cited by this paper
• Hyperhomocysteinemia and the development of chronic kidney disease in a general population: the Hisayama study.

  2004cited by this paper
• Structure and function of glutamate receptor ion channels.

  2004cited by this paper
• Altered NMDA receptor expression in renal toxicity: Protection with a receptor antagonist.

  2004cited by this paper
• Characterization and localization of a human serine racemase.

  2004cited by this paper
• Contribution of astrocytes to hippocampal long-term potentiation through release of d-serine

  2003cited by this paper
• Expression and developmental regulation of the NMDA receptor subunits in the kidney and cardiovascular system.

  2002cited by this paper
• Serum Homocysteine Levels Are Associated With the Development of (Micro)albuminuria: The Hoorn Study

  2001cited by this paper
• The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal death.

  2001cited by this paper
• Intersubunit cooperativity in the NMDA receptor.

  2001cited by this paper
• D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor.

  2000cited by this paper
• Transient Expression of NMDA Receptor Subunit NR2B in the Developing Rat Heart

  2000cited by this paper
• Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission.

  1999cited by this paper
• The glutamate receptor ion channels.

  1999influential reference
• The effect of folic acid fortification on plasma folate and total homocysteine concentrations.

  1999cited by this paper
• Homocysteine and atherothrombosis.

  1998influential reference
• Expression of an N-methyl-D-aspartate-type receptor by human and rat osteoblasts and osteoclasts suggests a novel glutamate signaling pathway in bone.

  1998cited by this paper
• Catecholamines modulate podocyte function.

  1998cited by this paper
• Identification of functional ionotropic glutamate receptor proteins in pancreatic β‐cells and in islets of Langerhans

  1995cited by this paper
• Expression and role of ionotropic glutamate receptors in pancreatic islet cells

  1995cited by this paper
• Rapid HPLC determination of total homocysteine and other thiols in serum and plasma: sex differences and correlation with cobalamin and folate concentrations in healthy subjects.

  1994cited by this paper
• Calcium permeability of the N-methyl-D-aspartate receptor channel in hippocampal neurons in culture.

  1993cited by this paper
• Inactivation of NMDA channels in cultured hippocampal neurons by intracellular calcium

  1993cited by this paper
• Excitotoxic cell death.

  1992cited by this paper
• Characterization of the binding of [3H]L-689,560, an antagonist for the glycine site on the N-methyl-D-aspartate receptor, to rat brain membranes.

  1992cited by this paper
• Hyperhomocyst(e)inemia as a risk factor for occlusive vascular disease.

  1992cited by this paper
• Glycine decreases desensitization of N-methyl-D-aspartate (NMDA) receptors expressed in Xenopus oocytes and is required for NMDA responses.

  1990cited by this paper
• Structure-activity relationships for amino acid transmitter candidates acting at N-methyl-D-aspartate and quisqualate receptors

  1990cited by this paper
• Antagonism of responses to excitatory amino acids on rat cortical neurones by the spider toxin, argiotoxin636

  1989cited by this paper
• NMDA receptor antagonists disrupt the retinotectal topographic map.

  1989cited by this paper
• Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes.

  1988cited by this paper
• Permeation and block of N‐methyl‐D‐aspartic acid receptor channels by divalent cations in mouse cultured central neurones.

  1987influential reference
• L-homocysteate is a potent neurotoxin on cultured cortical neurons.

  1987cited by this paper
• Glycine potentiates the NMDA response in cultured mouse brain neurons

  1987cited by this paper
• The presence of free D-aspartic acid in rodents and man.

  1986cited by this paper
• Voltage-dependent block by Mg2+ of NMDA responses in spinal cord neurones

  1984cited by this paper
• Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain.

  1984cited by this paper
• Excitatory amino acid receptors and synaptic excitation in the mammalian central nervous system.

  1979cited by this paper
• D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis.

  1975cited by this paper
• D-serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis.

  1975cited by this paper
• The nature of D-serine--induced nephrotoxicity.

  1974cited by this paper
• Activity Coefficients of Aqueous Sodium Chloride from 15{degrees} to 50{degrees}C Measured with a Glass Electrode.

  1968cited by this paper
• The thermodynamic activity of calcium ion in sodium chloride-calcium chloride electrolytes.

  1968cited by this paper
• Activity Coefficients of Aqueous Sodium Chloride from 15� to 50�C Measured with a Glass Electrode

  1968cited by this paper

• Evidence for conserved expression of genes annotated as associated with brain-related biological processes in human podocytes and brain.

  2026cites this paper
• Vesicular Glutamate Transporter 3 Is Involved in Glutamatergic Signalling in Podocytes

  2025cites this paper
• Kidney injury: An overlooked manifestation in autoimmune encephalitis.

  2024cites this paper
• Non-voltage gated Ca2+ channel signaling in glomerular cells in kidney health and disease.

  2024cites this paper
• NMDA receptors – regulatory function and pathophysiological significance for pancreatic beta cells

  2023cites this paper
• WITHDRAWN: NMDA Inhibitors: A Potential Contrivance to Assist in Management of Alzheimer Disease.

  2022cites this paper
• Insights into the regulation of podocyte and glomerular function by lactate and its metabolic sensor G‐protein‐coupled receptor 81

  2022cites this paper
• Ion channels and channelopathies in glomeruli.

  2022cites this paper
• Free d-Amino Acids in Salivary Gland in Rat

  2022cites this paper
• The Effect on the Kidney in Patients With Anti-N-methyl D-aspartate Receptor Antibody Encephalitis

  2021cites this paper
• Quercetin and vitamin E ameliorate cardio-apoptotic risks in diabetic rats

  2021cites this paper
• D-Serine: A Cross Species Review of Safety

  2021cites this paper
• NMDA Receptor Hypofunction in the Aging-Associated Malfunction of Peripheral Tissue

  2021cites this paper
• Acute D-Serine Co-Agonism of β-Cell NMDA Receptors Potentiates Glucose-Stimulated Insulin Secretion and Excitatory β-Cell Membrane Activity

  2021cites this paper
• Glutamate-Gated NMDA Receptors: Insights into the Function and Signaling in the Kidney

  2020cites this paper
• The Role of Calpain in Kidney Podocytes, in Health and Disease

  2020cites this paper
• The Role of NMDA Receptors in Alzheimer’s Disease

  2019cites this paper
• Autoimmune encephalitis (NMDAR antibody) in a patient receiving chronic post-transplant immunosuppression

  2018cites this paper
• The Role of Calpain in Kidney Podocytes, in Health and Disease

  2018cites this paper
• Functional Distribution and Regulation of the NMDAR in the Kidney, Heart and Parathyroid Gland

  2017cites this paper
• The effect of three angiotensin-converting enzyme inhibitors on kynurenic acid production in rat kidney in vitro

  2017cites this paper
• Physiological Roles of Non-Neuronal NMDA Receptors.

  2016cites this paper
• Renal NMDA Receptors Are Increased in the Akita Mouse Model of Type 1 Diabetes and NMDA Antagonists Reduce Diabetic Nephropathy

  2016cites this paper
• NMDA Receptors as Potential Therapeutic Targets in Diabetic Nephropathy: Increased Renal NMDA Receptor Subunit Expression in Akita Mice and Reduced Nephropathy Following Sustained Treatment With Memantine or MK-801

  2016cites this paper
• NMDA receptors participate in the progression of diabetic kidney disease by decreasing Cdc42‐GTP activation in podocytes

  2016cites this paper
• Roles of NMDARs in maintenance of the mouse cerebrovascular endothelial cell-constructed tight junction barrier.

  2016cites this paper
• Nicotine Induces Podocyte Apoptosis through Increasing Oxidative Stress

  2016cites this paper
• Glutamate receptors in the kidney.

  2015cites this paper
• The potential of targeting NMDA receptors outside the CNS

  2015influential citation
• Role of N-methyl-D-aspartate receptors in the regulation of human airway smooth muscle function and airway responsiveness

  2015cites this paper
• Molecular Pathogenesis of Anti-NMDAR Encephalitis

  2015cites this paper
• Ischemic Acute Kidney Injury Perturbs Homeostasis of Serine Enantiomers in the Body Fluid in Mice: Early Detection of Renal Dysfunction Using the Ratio of Serine Enantiomers

  2014cites this paper
• The role of calpain in kidney podocytes, in health and disease

  2014cites this paper
• Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli

  2014cites this paper
• A combinatorial approach of Proteomics and Systems Biology in unravelling the mechanisms of acute kidney injury (AKI): involvement of NMDA receptor GRIN1 in murine AKI

  2013cites this paper
• Is the Antiproteinuric Effect of Cyclosporine A Independent of Its Immunosuppressive Function in T Cells?

  2012cites this paper
• Calcium signaling in renal tubular cells.

  2012influential citation
• Sustained Activation of N-Methyl-d-Aspartate Receptors in Podoctyes Leads to Oxidative Stress, Mobilization of Transient Receptor Potential Canonical 6 Channels, Nuclear Factor of Activated T Cells Activation, and Apoptotic Cell Death

  2012influential citation
• Anti-NMDA receptor encephalitis. The disorder, the diagnosis and the immunobiology.

  2012cites this paper
• Strangers on a train: atypical glutamate receptors in the kidney glomerulus. Focus on "Functional NMDA receptors with atypical properties are expressed in podocytes".

  2011cites this paper
• Calcium mediates glomerular filtration through calcineurin and mTORC2/Akt signaling.

  2011cites this paper
• Tubal damage, infertility and tubal ectopic pregnancy: Chlamydia trachomatis and other microbial aetiologies

  2011cites this paper