New cerebellar phenotypes in YAC transgenic mouse in vivo library of human Down syndrome critical region-1.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2007-12-21

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.BBRC.2007.10.035PMID 17963726
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mental retardation in Down syndrome: from gene dosage imbalance to molecular and cellular mechanisms.

  2007cited by this paper
• Identification of pathways regulating cell size and cell-cycle progression by RNAi

  2006cited by this paper
• Mon2, a Relative of Large Arf Exchange Factors, Recruits Dop1 to the Golgi Apparatus*

  2006cited by this paper
• Claudins and epithelial paracellular transport.

  2006cited by this paper
• C21orf5, a new member of Dopey family involved in morphogenesis, could participate in neurological alterations and mental retardation in Down syndrome.

  2005cited by this paper
• C21orf5, a human candidate gene for brain abnormalities and mental retardation in Down syndrome

  2005cited by this paper
• Epidemiology of Down syndrome in 118,265 consecutive births.

  2005cited by this paper
• A Chromosome 21 Critical Region Does Not Cause Specific Down Syndrome Phenotypes

  2004cited by this paper
• Silencing of Chromatin Assembly Factor 1 in Human Cells Leads to Cell Death and Loss of Chromatin Assembly during DNA Synthesis

  2004cited by this paper
• Transgenic Mouse In Vivo Library of Human Down Syndrome Critical Region 1: Association between DYRK1A Overexpression, Brain Development Abnormalities, and Cell Cycle Protein Alteration

  2004cited by this paper
• Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome.

  2004cited by this paper
• Reduction of chromatin assembly factor 1 p60 and C21orf2 protein, encoded on chromosome 21, in Down syndrome brain.

  2003cited by this paper
• The differentially expressed C21orf5 gene in the medial temporal-lobe system could play a role in mental retardation in Down syndrome and transgenic mice.

  2003cited by this paper
• Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: Challenging the gene dosage effect hypothesis (Part I)

  2003cited by this paper
• Protein levels of genes encoded on chromosome 21 in fetal Down syndrome brain: Challenging the gene dosage effect hypothesis (Part II)

  2003cited by this paper
• The Newly Identified Human Nuclear Protein NXP-2 Possesses Three Distinct Domains, the Nuclear Matrix-binding, RNA-binding, and Coiled-coil Domains*

  2002cited by this paper
• Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29.

  2001cited by this paper
• Discovery and genetic localization of Down syndrome cerebellar phenotypes using the Ts65Dn mouse.

  2000cited by this paper
• C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning.

  2000cited by this paper
• Morphogenesis in Aspergillus nidulans requires Dopey (DopA), a member of a novel family of leucine zipper‐like proteins conserved from yeast to humans

  2000cited by this paper
• 10 years of Genomics, chromosome 21, and Down syndrome.

  1998cited by this paper
• SET domain proteins modulate chromatin domains in eu- and heterochromatin

  1998cited by this paper
• Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

  1997cited by this paper
• Cerebellar volume in adults with Down syndrome.

  1997cited by this paper
• Cerebellar Contribution to Spatial Event Processing: Morris Water Maze and T‐maze

  1996cited by this paper
• The yeast genome project: what did we learn?

  1996cited by this paper
• The neuropsychology of mental retardation

  1996cited by this paper
• Selective neuroanatornic abnormalities in Down's syndrome and their cognitive correlates

  1995cited by this paper
• The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication.

  1995cited by this paper
• Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2.

  1995cited by this paper
• A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum.

  1995cited by this paper
• Abnormal embryonic cerebellar development and patterning of postnatal foliation in two mouse Engrailed-2 mutants.

  1994cited by this paper
• Molecular Mapping of Twenty-Four Features of Down Syndrome on Chromosome 21

  1993cited by this paper
• Immunohistochemical localization of carbonyl reductase in human tissues.

  1992cited by this paper

• Dopey2 and Pcdh7 orchestrate the development of embryonic neural stem cells/ progenitors in zebrafish

  2023cites this paper
• Modeling Down syndrome in animals from the early stage to the 4.0 models and next.

  2020cites this paper
• Cerebellar alterations in a model of Down syndrome: The role of the Dyrk1A gene.

  2018influential citation
• Rodent models in Down syndrome research: impact and future opportunities

  2017cites this paper
• Animal and model systems for studying cystic fibrosis.

  2017cites this paper
• Mental Retardation and Human Chromosome 21 Gene Overdosage : From Functional Genomics and Molecular Mechanisms Towards Prevention and Treatment of the Neuropathogenesis of Down Syndrome

  2017influential citation
• Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks

  2014cites this paper
• Molecular Pathways of Down Syndrome Critical Region Genes

  2013cites this paper
• Using C. elegans to Decipher the Cellular and Molecular Mechanisms Underlying Neurodevelopmental Disorders

  2013cites this paper
• The in vivo Down syndrome genomic library in mouse.

  2012cites this paper
• Mental Retardation and Human Chromosome 21 Gene Overdosage: From Functional Genomics and Molecular Mechanisms Towards Prevention and Treatment of the Neuropathogenesis of Down Syndrome

  2011influential citation
• Molecular and cellular mechanisms elucidating neurocognitive basis of functional impairments associated with intellectual disability in Down syndrome.

  2010cites this paper
• A quantitative assessment of gene expression (QAGE) reveals differential overexpression of DOPEY2, a candidate gene for mental retardation, in Down syndrome brain regions

  2009influential citation