Continuous Postoperative Antibiotic Irrigation via Catheter System Following Immediate Breast Reconstruction

Breast reconstruction with implantable devices is now the most common type of technique utilized following mastectomy. Because infections are one of the most common complications for the procedure and currently no one method has been proven to stand above the rest, we designed and implemented a novel technique that employed 24 hours continuous triple-antibiotic irrigation via a catheter-based system. From August 2009 to March 2012, 79 patients underwent tissue expander-based reconstruction from a single plastic surgeon. Forty-five consecutive patients underwent breast reconstructive surgery with implant-based reconstruction alone; the remaining 34 patients underwent breast reconstructive surgery with tissue expansion and closed continuous postoperative antibiotic irrigation. Incidences of infection, seroma, hematoma, and premature explantation were recorded. Both the rate of premature explant (20% vs 2.9%; P = 0.037) and surgical site infections (22.2% vs 5.8%, P = 0.060) decreased. Twenty-four hour continuous antibiotic irrigation is a useful adjunct to tissue expander breast reconstruction.

• Publication year

  2015

• Venue

  ePlasty: Open Access Journal of Plastic and Reconstructive Surgery

• Publication date

  2015-11-13

• Fields of study

  Medicine

• Identifiers
  PMID 26664672PMCID 4655785
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Intraperitoneal chemotherapy for peritoneal surface malignancy: experience with 1,000 patients.

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• Prophylactic antibiotics in aesthetic surgery.

  2006cited by this paper
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  2006cited by this paper
• Infection in breast implants.

  2005cited by this paper
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  2005cited by this paper
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  2003cited by this paper
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  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  1999cited by this paper
• Perioperative normothermia to reduce the incidence of surgical-wound infection and shorten hospitalization. Study of Wound Infection and Temperature Group.

  1996cited by this paper
• Microbial Evaluation: 139 Implants Removed from Symptomatic Patients

  1996cited by this paper
• Complications of mastectomy and their relationship to biopsy technique

  1996cited by this paper
• Clinical relevance of positive breast periprosthetic cultures without overt infection.

  1995cited by this paper
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  1995cited by this paper
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  1993cited by this paper
• Wound complications after modified radical mastectomy compared with tylectomy with axillary lymph node dissection.

  1991cited by this paper
• Studies on the Endogenous Flora of the Human Breast

  1988cited by this paper
• Dupuytren's contracture: wound irrigation to prevent hematoma.

  1987cited by this paper
• A Dressing System Providing Fluid Supply and Suction Drainage Used for Continuous or Intermittent Irrigation

  1986cited by this paper
• Capsular Contracture: A Prospective Study of the Effect of Local Antibacterial Agents

  1986cited by this paper
• [Treatment of infected wounds].

  1986cited by this paper
• The influence of hair-removal methods on wound infections.

  1983cited by this paper
• Does Infection Play a Role in Breast Capsular Contracture?

  1981cited by this paper
• Wound infections after preoperative depilatory versus razor preparation.

  1971cited by this paper
• Augmentation mammaplasty. Survey of complications in 10,941 patients by 265 surgeons.

  1970cited by this paper

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