Castleman’s Disease of the Cervical Region: A Pediatric Case Report

Castleman hastaligi (CH) kotu huylu olmayan lenf bezlerinin buyumeleri ile karakterize sik gorulmeyen bir hastaliktir. Etiyolojisi ve nedeni tam olarak bilinmemektedir (1). Ilk defa Castleman ve Towne (2) tarafindan genis mediastinal lenf nodu hiperplazisi saptanan bir hasta grubunda tanimlanmistir. CH’nin klinik formu iki tanedir: Cogunlukla buyume hizi yavas olan kitle biciminde meydana gelen lokalize form ve iki ve daha fazla bolgeyi kontrolune alan multisentrik form. Hastaligin uc histopatolojik tipi vardir. Daha sik gorulen tipi hiyalin vaskulerdir ve lokalize hastalik seklindedir. Tipik olarak asemptomatiktir ve yavas buyuyen kitle vardir (3). Cok sik gorulmeyen plazma hucreli tip cogunlukla multisentriktir (4). Bazi durumlarda hiyalin vaskuler ve plazma hucreli tipe ait bulgular beraber gorulebilir. Mikst olarak adlandirilan bu tip olguda taninin koyulmasi patolojik bulgulara ve hastaligin klinik seyrine baglidir (5). Genellikle yerlestigi bolge mediyastinal olan, boyun kitlelerinin sik gorulmeyen bir nedenidir. Bu olgu boyunda kitle ile basvuran cocuk hastalarda CH’nin ayirici tanida dusunulmesi gerektigini vurgulamak amaci ile sunulmustur.

• Publication year

  2016

• Venue

  Journal of Pediatric Research

• Publication date

  2016-06-15

• Fields of study

  Not labeled

• Identifiers
  DOI 10.4274/JPR.76588
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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