6-Aminonicotinamide and acute degenerative changes in the central nervous system.

No abstract is available for this paper.

• Publication year

  1958

• Venue

  Science

• Publication date

  1958-03-21

• Fields of study

  Medicine

• Identifiers
  DOI 10.1126/SCIENCE.127.3299.644-APMID 13529030
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Quantitative biochemical differences between tumor and host as a basis for cancer chemotherapy. V. Niacin and 6-aminonicotinamide.

  1957cited by this paper
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  1955cited by this paper
• 6-Aminonicotinamide--a Potent Nicotinamide Antagonist.

  1955cited by this paper
• The inhibition of sulphanilamide acetylation by aromatic and heterocyclic carboxamides and carboxhydrazides.

  1955cited by this paper
• Niacin and anti-niacin activity of 3-acetylpyridine in dogs.

  1955cited by this paper
• Significance of Enzymatically Catalyzed Exchange Reactions in Chemotherapy

  1954cited by this paper

• Effects of 6-Aminonicotinic Acid Esters on the Reprogrammed Epigenetic State of Distant Metastatic Pancreatic Carcinoma.

  2022cites this paper
• Cellular and biochemical alterations in L6 myoblast cells induced by 6‐aminonicotinamide

  2007cites this paper
• Clinical Experience with 6-aminonicotinamide Updated Version Citing Articles E-mail Alerts

  2006cites this paper
• Clinical Experience with 6-Aminonicotinamide FREDERICP

  2006cites this paper
• -P-NITROPHENYLUREA OCULAR TOXICITY IN MAN AND AN ANIMAL MODEL

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• Aminonicotinamide Sensitizes Human Tumor Cell Lines to Cisplatin 1

  2005cites this paper
• Histochemical changes in the rat spinal cord after exposure to 6-aminonicotinamide

  2004cites this paper
• Distribution of 3H-labelled 6-aminonicotinamide and accumulation of 6-Phosphogluconate in the spinal cord

  2004cites this paper
• Histochemical changes in the spinal cord after acute poisoning with 6-aminonicotinamide

  2004cites this paper
• Ultrastructure of 6-aminonicotinamide (6-AN)-induced lesions in the central nervous system of rats

  2004cites this paper
• Decreased glycolytic flux rate in the isolated perfused rat brain after pretreatment with 6-aminonicotinamide

  2004cites this paper
• Correlated changes in neuronal cerebral rat brain RNA synthesis and hypo- and hypermotoric disorders induced by 6-aminonicotinamide (6-AN)

  2004cites this paper
• Neurotoxin 6-aminonicotinamide affects levels of soluble proteins and enzyme activities in various tissues of golden hamsters.

  2000cites this paper
• Effect of 6-aminonicotinamide and other protein synthesis inhibitors on formation of platinum-DNA adducts and cisplatin sensitivity.

  2000cites this paper
• Murine pharmacokinetics of 6-aminonicotinamide (NSC 21206), a novel biochemical modulating agent.

  1999cites this paper
• Spongiform neuropathy induced in dogs by prolonged, low-level administration of 6-aminonicotinamide (6-ANA).

  1998cites this paper
• 6-Aminonicotinamide sensitizes human tumor cell lines to cisplatin.

  1998cites this paper
• Effect of 6-aminonicotinamide on metabolism of astrocytes and C6-glioma cells

  1997cites this paper
• Neurotoxic Synthesis by Enzymatic Error

  1994cites this paper
• Glucose and ketone body utilization by the brain of neonatal rats.

  1993cites this paper
• Studies of activated microglia and macrophages in lumbosacral spinal cord following an intraperitoneal injection of 6-aminonicotinamide into adult rats.

  1993cites this paper
• Quantitative histochemical changes in enzymes involved in energy metabolism in the rat brain during postnatal development. II. Glucose‐6‐phosphate dehydrogenase and β‐hydroxybutyrate dehydrogenase

  1992cites this paper
• Effect of 6-aminonicotinamide on pentose cycle activity in isolated hepatocytes.

  1990cites this paper
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  1988cites this paper
• Alternative pathways of glucose utilization in developing rat spinal cord.

  1988cites this paper
• Regulation of the pentose phosphate pathway in human astrocytes and gliomas

  1987cites this paper
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  1986cites this paper
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  1986cites this paper
• Cerebral Energy Metabolism and Metabolic Encephalopathy

  1985cites this paper
• Niacin-Nicotinamide Deficiency

  1985cites this paper
• Pathology of 6-aminonicotinamide toxicosis in the rabbit.

  1985cites this paper
• 6‐Aminonicotinamide-lnduced Hydrocephalus in Suckling Mice

  1984cites this paper
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  1981cites this paper
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  1981cites this paper
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  1980cites this paper
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  1979cites this paper
• Diabetes mellitus and neuropathy following Vacor ingestion in man.

  1979cites this paper
• Effects of paraplegia produced by intrathecal 6-aminonicotinamide on motor units in the rat.

  1979cites this paper
• Is kernicterus due to inhibition of brain hexose-monophosphate shunt activity by bilirubin?

  1979cites this paper
• Physiological, biochemical and histological changes in skeletal muscle, neuromuscular junction and spinal cord of rats rendered paraplegic by subarachnoidal administration of 6-aminonicotinamide.

  1978cites this paper
• Ultrastructure of 6-aminonicotinamide (6-AN) —Induced lesions in the central nervous system of rats

  1978cites this paper
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  1978cites this paper
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  1978cites this paper
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  1978cites this paper
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  1978cites this paper
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  1977cites this paper
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  1977cites this paper
• Spastic paresis after 6-aminonicotinamide: Metabolic disorders in the spinal cord and electromyographically recorded changes in the hind limbs of rats

  1976cites this paper
• NEUROTROPHIC CONTROL OF THE FAST AND SLOW SKELETAL MUSCLE

  1976cites this paper
• Decreased GABA and glutamate concentration in rat brain after treatment with 6-aminonicotinamide

  1976cites this paper
• Influences of Experimental Brain Edema on the Development of the Visual System

  1975cites this paper
• [Light- and electron microscopy studies on the cerebellum in 12-day-old rats after treatment with 6-aminonicotinamide (6-AN)].

  1975cites this paper
• Electronmicroscopic study of the effect of 6-AN on the sciatic nerve in newborn rats

  1975cites this paper
• [The pathomorphology of the central nervous system in carbon tetrachloride poisoning. 5. Pathohistology of the myelon in animal experiments on randomly bred rabbits].

  1974cites this paper
• Effects of 3-acetylpyridine on the central nervous system of the rat, as demonstrated by silver methods.

  1974cites this paper
• Acute gliopathy in spinal cord and brain stem induced by 6-aminonicotinamide

  1974cites this paper
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  1974cites this paper
• Antimetabolic Action on the Pentose Phosphate Pathway in the Central Nervous System Induced by 6-Aminonicotinamide

  1974cites this paper
• [Experimental myelopathy--biochemical basis of its cellular pathogenesis (author's transl)].

  1973cites this paper
• Neurotoxic effects of 6-aminonicotinamide on cultures of central nervous tissue

  1973cites this paper
• Ultrastruktur der Glia- und Axonschädigung durch 6-Aminonicotinamid (6 An) am Sehnerv der Ratte

  1973cites this paper
• Experimentelle Myelopathie — Biochemische Grundlagenforschung ihrer cellulären Pathogenese

  1973cites this paper
• [Ultrastructure of glial and axonal changes in the optic nerve of the rat induced by 6-aminonicotinamide (author's transl)].

  1973cites this paper
• 4 – Nonspecific Changes of the Central Nervous System in Normal and Experimental Material

  1972cites this paper
• [Differentiation of functional disturbances of the central nervous system evoked by 6-aminonicotinamide, an antimetabolite of nicotinamide].

  1970cites this paper
• Untersuchungen zur Differenzierung der durch 6-Aminonicotinamid, einem Antimetaboliten des Nicotinamids, hervorgerufenen zentralnervösen Funktionsstörungen

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• [Brain carbohydrate metabolism following blockade of the pentose phosphate pathway by 6-aminonicotinamide].

  1970cites this paper
• Brain disorders induced by pharmacological blockade of the pentose phosphate pathway.

  1969cites this paper
• [Behavior changes and neuropathology in 3-acetylpyridine poisoning in rats].

  1968cites this paper
• Biosynthesis and action of dinucleotides containing 6-aminonicotinamide on membrane transport processes.

  1968cites this paper
• [Morphological findings in the central nervous system of the rat after poisoning with antimetabolites of nicotinamide (6-aminonicotinamide and 3-acetylpyridine) and a quinoline derivative (5-nitro-8-hydroxyquinoline)].

  1968cites this paper
• Verhaltensänderung und Neuropathologie bei der 3-Acetylpyridinvergiftung der Ratte

  1968cites this paper
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  1968cites this paper
• DRUG-INDUCED PATHOBIOTIC EFFECTS

  1968cites this paper
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  1967cites this paper
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  1966cites this paper
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  1965cites this paper
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  1965cites this paper
• [THE ACTIVITY OF NAD AND NADP-DEPENDENT ENZYMES IN DIFFERENT SEGMENTS OF THE RAT BRAIN].

  1964cites this paper
• Die Aktivität NAD- und NADP-abhängiger Enzyme in verschiedenen Teilen des Rattengehirns

  1964cites this paper
• [DAMAGE TO THE CENTRAL NERVOUS SYSTEM BY ANTIMETABOLITES OF NICOTINAMIDE. A CONTRIBUTION TO MOLECULAR PATHOLOGY OF PYRIDINE NUCLEOTIDES].

  1963cites this paper
• Repeated Homing Exhibited by a Female Pallid Bat

  1962cites this paper
• Clinical use of 6‐aminonicotinamide in patients with disseminated neoplastic disease

  1961cites this paper
• Clinical experience with 6-aminonicotinamide.

  1961cites this paper
• The brain and the poison.

  1959cites this paper
• Effect of Temperature Extremes and Cortisone on Toxicity of Diphosphopyridine Nucleotide in Mice

  1959cites this paper
• Quantitative biochemical differences between tumor and host tissue. VI. 6-Aminonicotinamide antagonism of DPN-dependent enzymatic systems.

  1958cites this paper