The genetic framework for development of nephrolithiasis

Over 1%–15% of the population worldwide is affected by nephrolithiasis, which remains the most common and costly disease that urologists manage today. Identification of at-risk individuals remains a theoretical and technological challenge. The search for monogenic causes of stone disease has been largely unfruitful and a technological challenge; however, several candidate genes have been implicated in the development of nephrolithiasis. In this review, we will review current data on the genetic inheritance of stone disease, as well as investigate the evolving role of genetic analysis and counseling in the management of nephrolithiasis.

• Publication year

  2016

• Venue

  Asian Journal of Urology

• Publication date

  2016-11-28

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.ajur.2016.11.003PMID 29264202PMCID 5730897
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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