Chronic treatment with diazepam or the inverse benzodiazepine receptor agonist FG 7142 causes differential changes in the effects of GABA receptor stimulation.

No abstract is available for this paper.

• Publication year

  1988

• Venue

  Epilepsy Research

• Publication date

  1988-07-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1016/0920-1211(88)90016-2PMID 2848700
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Tolerance to the benzodiazepine diazepam in an animal model of anxiolytic activity

  2004cited by this paper
• Decreased sensitivity to benzodiazepine receptor agonists and increased sensitivity to inverse agonists following chronic treatments: evidence for separate mechanisms.

  1988cited by this paper
• Chronic treatment with lorazepam and FG 7142 may change the effects of benzodiazepine receptor agonists, antagonists and inverse agonists by different mechanisms.

  1987cited by this paper
• Behavioral and biochemical evidence for a long-lasting decrease in GABAergic function elicited by chronic administration of FG 7142

  1986cited by this paper
• Behavioural and biochemical evidence for a long-lasting decrease in GABAergic function elicited by chronic administration of FG 7142.

  1986cited by this paper
• Physical dependence on clonazepam in dogs.

  1986cited by this paper
• The effects of drugs acting at the GABAA‐receptor/ionophore after chemical kindling with the benzodiazepine receptor ligand FG 7142

  1986cited by this paper
• Spontaneous and RO 15-1788-induced reversal of subsensitivity to GABA following chronic benzodiazepines.

  1985cited by this paper
• Effects of repeated RO 15-1788 administration in benzodiazepine-dependent baboons.

  1985cited by this paper
• Tolerance to the behavioral actions of benzodiazepines.

  1985cited by this paper
• Chronic administration of diazepam to rats causes changes in EEG patterns and in coupling between GABA receptors and benzodiazepine binding sites in vitro.

  1984cited by this paper
• Benzodiazepine receptors.

  1984cited by this paper
• Chronic benzodiazepine treatment decreases postsynaptic GABA sensitivity

  1984cited by this paper
• β-Carbolines with agonistic and inverse agonistic properties at benzodiazepine receptors of the rat

  1984cited by this paper
• Acute and chronic effects of the benzodiazepine receptor ligand FG 7142: proconvulsant properties and kindling

  1984cited by this paper
• Differential pharmacological effects of benzodiazepine receptor inverse agonists.

  1983cited by this paper
• Comparative assay of anticonvulsant and toxic potencies of sixteen GABAmimetic drugs.

  1982cited by this paper
• A three-state model of the benzodiazepine receptor explains the interactions between the benzodiazepine antagonist Ro 15-1788, benzodiazepine tranquilizers, β-carbolines, and phenobarbitone

  1982cited by this paper
• Interaction of convulsive ligands with benzodiazepine receptors.

  1982cited by this paper
• The GABA postsynaptic membrane receptor-ionophore complex

  1981cited by this paper
• Studies on the post-ictal rise in seizure threshold.

  1981cited by this paper
• Dependence, tolerance, and addiction to benzodiazepines: clinical and pharmacokinetic considerations.

  1978cited by this paper
• Benzodiasepine and neurotransmitter receptor binding in rat brain after chronic administration of diazepam or phenobarbital.

  1978cited by this paper
• Central monoamines and convulsine thresholds in mice and rats.

  1973cited by this paper
• Experimental Models of Epilepsy--a Manual for the Laboratory Worker

  1972cited by this paper
• Chemical protection against ionizing radiation. I. Sampling methods for screening compounds in radiation protection studies with mice.

  1957cited by this paper
• Electrically Induced Convulsions

  1940cited by this paper

• COLORcation: A new application to phenotype exploratory behavior models of anxiety in mice.

  2016cites this paper
• Anti-Epileptic Activity

  2016cites this paper
• Neuroadaptive processes in GABAergic and glutamatergic systems in benzodiazepine dependence.

  2003cites this paper
• Psychotropic and neurotropic activity

  1997cites this paper
• Effects of early protein malnutrition and environmental stimulation upon the reactivity to diazepam in two animal models of anxiety.

  1994cites this paper
• [Quantitative clinical and EEG measures of epileptogenesis in temporal lobe epilepsy].

  1994cites this paper
• Kindling to the benzodiazepine receptor inverse agonist, FG 7142: evidence for involvement of NMDA, but not non-NMDA, glutamatergic receptors.

  1993cites this paper
• Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.

  1991cites this paper
• Behavioral effects of benzodiazepine ligands in non-dependent, diazepam-dependent and diazepam-withdrawn baboons.

  1991cites this paper
• Muscimol-associated changes in local cerebral glucose use following chronic diazepam administration.

  1991cites this paper
• Augmentation of GABAA receptor function by chronic exposure to GABA-neutral and GABA-negative benzodiazepine ligands in cultured cortical neurons.

  1990cites this paper
• Chronic handling modifies the anxiolytic effect of diazepam in the elevated plus-maze.

  1990cites this paper
• GABAergic and dopaminergic transmission in the rat cerebral cortex: effect of stress, anxiolytic and anxiogenic drugs.

  1990cites this paper
• Behavioral differentiation of benzodiazepine ligands after repeated administration in baboons.

  1989cites this paper
• Blockade of FG 7142 kindling by anticonvulsants acting at sites distant from the benzodiazepine receptor.

  1989cites this paper
• Co-existence of kindling induced by the beta-carboline, FG 7142, and tolerance to diazepam following chronic treatment in mice.

  1988cites this paper