Protein Kinase A Contributes to the Negative Control of Snf1 Protein Kinase in Saccharomyces cerevisiae

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Eukaryotic Cell

• Publication date

  2011-12-02

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/EC.05061-11PMID 22140226PMCID PMC3272905
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Inaugural Article: Roles of two protein phosphatases, Reg1-Glc7 and Sit4, and glycogen synthesis in regulation of SNF1 protein kinase

  2011cited by this paper
• Interaction of SNF1 Protein Kinase with Its Activating Kinase Sak1

  2011cited by this paper
• Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer.

  2010cited by this paper
• Ime1 and Ime2 Are Required for Pseudohyphal Growth of Saccharomyces cerevisiae on Nonfermentable Carbon Sources

  2010cited by this paper
• PKA phosphorylates and inactivates AMPKα to promote efficient lipolysis

  2010cited by this paper
• Systems biology of energy homeostasis in yeast.

  2010cited by this paper
• Roles of the Snf1-Activating Kinases during Nitrogen Limitation and Pseudohyphal Differentiation in Saccharomyces cerevisiae

  2009cited by this paper
• Uncoupling of the LKB1-AMPKα Energy Sensor Pathway by Growth Factors and Oncogenic BRAFV600E

  2009cited by this paper
• Glucose regulates transcription in yeast through a network of signaling pathways

  2009cited by this paper
• SNF1/AMPK pathways in yeast.

  2008cited by this paper
• AMPK phosphorylation of raptor mediates a metabolic checkpoint.

  2008cited by this paper
• Detection of endogenous Snf1 and its activation state: application to Saccharomyces and Candida species

  2008cited by this paper
• How Saccharomyces responds to nutrients.

  2008cited by this paper
• The checkpoint kinase Hsl1p is activated by Elm1p-dependent phosphorylation.

  2008cited by this paper
• AMP-activated protein kinase as a drug target.

  2007cited by this paper
• AMPK and SNF1: Snuffing Out Stress

  2007cited by this paper
• Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth.

  2007cited by this paper
• AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

  2007cited by this paper
• LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons.

  2007cited by this paper
• Regulation of Snf1 Protein Kinase in Response to Environmental Stress*

  2007cited by this paper
• LKB1/STRAD promotes axon initiation during neuronal polarization.

  2007cited by this paper
• Mammalian TAK1 Activates Snf1 Protein Kinase in Yeast and Phosphorylates AMP-activated Protein Kinase in Vitro*

  2006cited by this paper
• Nitrogen Availability and TOR Regulate the Snf1 Protein Kinase in Saccharomyces cerevisiae

  2006cited by this paper
• Direct Phosphorylation and Activation of a Nim1-related Kinase Gin4 by Elm1 in Budding Yeast*

  2006cited by this paper
• Glucose Signaling in Saccharomyces cerevisiae

  2006cited by this paper
• Regulatory Domains of Snf1-Activating Kinases Determine Pathway Specificity

  2006influential reference
• Function of Mammalian LKB1 and Ca2+/Calmodulin-dependent Protein Kinase Kinase α as Snf1-activating Kinases in Yeast*

  2005cited by this paper
• Snf1 kinase complexes with different beta subunits display stress-dependent preferences for the three Snf1-activating kinases

  2005cited by this paper
• AMP-activated protein kinase induces a p53-dependent metabolic checkpoint.

  2005cited by this paper
• The Ca2+/Calmodulin-dependent Protein Kinase Kinases Are AMP-activated Protein Kinase Kinases*

  2005cited by this paper
• Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.

  2005cited by this paper
• Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase.

  2005cited by this paper
• Cyclic AMP-Dependent Protein Kinase Regulates the Subcellular Localization of Snf1-Sip1 Protein Kinase

  2004cited by this paper
• Genetic and epigenetic regulation of the FLO gene family generates cell-surface variation in yeast.

  2004cited by this paper
• Pak1 Protein Kinase Regulates Activation and Nuclear Localization of Snf1-Gal83 Protein Kinase

  2004cited by this paper
• Activation of the RAS/Cyclic AMP Pathway Suppresses a TOR Deficiency in Yeast

  2004cited by this paper
• Elm1p is one of three upstream kinases for the Saccharomyces cerevisiae SNF1 complex.

  2003cited by this paper
• Std1p (Msn3p) positively regulates the Snf1 kinase in Saccharomyces cerevisiae.

  2003cited by this paper
• Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade

  2003cited by this paper
• TSC2 mediates cellular energy response to control cell growth and survival.

  2003cited by this paper
• Yeast Pak1 Kinase Associates with and Activates Snf1

  2003cited by this paper
• Activation of yeast Snf1 and mammalian AMP-activated protein kinase by upstream kinases

  2003influential reference
• Convergence of TOR-Nitrogen and Snf1-Glucose Signaling Pathways onto Gln3

  2002cited by this paper
• Purification and Characterization of Snf1 Kinase Complexes Containing a Defined β Subunit Composition*

  2002cited by this paper
• The Gα Protein Gpa2 Controls Yeast Differentiation by Interacting with Kelch Repeat Proteins that Mimic Gβ Subunits

  2002cited by this paper
• The Galpha protein Gpa2 controls yeast differentiation by interacting with kelch repeat proteins that mimic Gbeta subunits.

  2002cited by this paper
• Snf1 Protein Kinase and the Repressors Nrg1 and Nrg2 Regulate FLO11, Haploid Invasive Growth, and Diploid Pseudohyphal Differentiation

  2002cited by this paper
• Purification and characterization of Snf1 kinase complexes containing a defined Beta subunit composition.

  2002cited by this paper
• Regulation of Snf1 Kinase ACTIVATION REQUIRES PHOSPHORYLATION OF THREONINE 210 BY AN UPSTREAM KINASE AS WELL AS A DISTINCT STEP MEDIATED BY THE Snf4 SUBUNIT*

  2001cited by this paper
• Role of the yeast Snf1 protein kinase in invasive growth.

  2001cited by this paper
• Physiological substrates of cAMP-dependent protein kinase.

  2001cited by this paper
• Regulation of Snf1 Kinase

  2001cited by this paper
• The G protein-coupled receptor gpr1 is a nutrient sensor that regulates pseudohyphal differentiation in Saccharomyces cerevisiae.

  2000cited by this paper
• A regulatory shortcut between the Snf1 protein kinase and RNA polymerase II holoenzyme.

  2000cited by this paper
• LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo.

  2000cited by this paper
• The Yeast Ras/Cyclic AMP Pathway Induces Invasive Growth by Suppressing the Cellular Stress Response

  1999cited by this paper
• Nim1-related kinases coordinate cell cycle progression with the organization of the peripheral cytoskeleton in yeast.

  1999cited by this paper
• Cyclic AMP-Dependent Protein Kinase Regulates Pseudohyphal Differentiation in Saccharomyces cerevisiae

  1999cited by this paper
• Characterization of Saccharomyces cerevisiae strains expressing ira1 mutant alleles modeled after disease-causing mutations in NF1

  1999cited by this paper
• Functional Relationships of Srb10-Srb11 Kinase, Carboxy-Terminal Domain Kinase CTDK-I, and Transcriptional Corepressor Ssn6-Tup1

  1998cited by this paper
• Snf1 Protein Kinase Regulates Phosphorylation of the Mig1 Repressor in Saccharomyces cerevisiae

  1998cited by this paper
• Expression of the SUC2 Gene of Saccharomyces cerevisiae is Induced by Low Levels of Glucose

  1997cited by this paper
• The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex

  1997cited by this paper
• Genetic aspects of carbon catabolite repression of the STA2 glucoamylase gene in Saccharomyces cerevisiae

  1996cited by this paper
• REG1 binds to protein phosphatase type 1 and regulates glucose repression in Saccharomyces cerevisiae.

  1995cited by this paper
• Characterization of glycogen-deficient glc mutants of Saccharomyces cerevisiae.

  1994cited by this paper
• A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex.

  1994cited by this paper
• The GLC7 type 1 protein phosphatase is required for glucose repression in Saccharomyces cerevisiae

  1994cited by this paper
• Genes required for derepression of an extracellular glucoamylase gene, STA2, in the yeast Saccharomyces

  1993cited by this paper
• Regulation of dimorphism in Saccharomyces cerevisiae: involvement of the novel protein kinase homolog Elm1p and protein phosphatase 2A

  1993cited by this paper
• Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases.

  1991cited by this paper
• RAS genes in Saccharomyces cerevisiae: signal transduction in search of a pathway.

  1991cited by this paper
• Deletion of SNF1 affects the nutrient response of yeast and resembles mutations which activate the adenylate cyclase pathway.

  1991cited by this paper
• IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein.

  1990influential reference
• The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae.

  1990cited by this paper
• S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein.

  1990influential reference
• A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

  1989cited by this paper
• Methods in Yeast Genetics: A Laboratory Course Manual

  1987influential reference
• Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase.

  1987cited by this paper
• Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae

  1987cited by this paper
• Characterization of Saccharomyces cerevisiae genes encoding subunits of cyclic AMP-dependent protein kinase

  1987cited by this paper
• In yeast, RAS proteins are controlling elements of adenylate cyclase.

  1985cited by this paper
• Mutants of yeast defective in sucrose utilization.

  1981cited by this paper
• Genetics of carbon catabolite repression in Saccharomyces cerevisiae: genes involved in the derepression process

  1977cited by this paper
• Isolation and characterization of yeast mutants defective in intermediary carbon metabolism and in carbon catabolite derepression

  1977cited by this paper

• Rewiring energy homeostasis in Yarrowia lipolytica enables efficient terpenoid biosynthesis

  2026cites this paper
• TOR and heat shock response pathways regulate peroxisome biogenesis during proteotoxic stress

  2025cites this paper
• The Yeast Gsk-3 Kinase Mck1 Is Necessary for Cell Wall Remodeling in Glucose-Starved and Cell Wall-Stressed Cells

  2025cites this paper
• Gut health benefits and associated systemic effects provided by functional components from the fermentation of natural matrices.

  2024cites this paper
• Reactive oxygen species-mediated signal transduction and utilization strategies in microalgae.

  2024cites this paper
• The polyHIS Tract of Yeast AMPK Coordinates Carbon Metabolism with Iron Availability

  2023cites this paper
• Advances in S. cerevisiae Engineering for Xylose Fermentation and Biofuel Production: Balancing Growth, Metabolism, and Defense

  2023cites this paper
• Glucose Inhibits Yeast AMPK (Snf1) by Three Independent Mechanisms

  2023cites this paper
• The novel properties of Kluyveromyces marxianus glucose sensor/receptor repressor pathway and the construction of glucose repression-released strains

  2023cites this paper
• Regulation of yeast Snf1 (AMPK) by a polyhistidine containing pH sensing module

  2022cites this paper
• AMPK Phosphorylation Is Controlled by Glucose Transport Rate in a PKA-Independent Manner

  2021cites this paper
• Lipid biosynthesis mediated by the cyclic adenosine monophosphate (cAMP) signaling pathway in Chlorella pyrenoidosa under salt-induced osmotic stress

  2021cites this paper
• Genome-Wide Analysis of Nutrient Signaling Pathways Conserved in Arbuscular Mycorrhizal Fungi

  2021cites this paper
• Identification and Characterization of Rapidly Accumulating sch9Δ Suppressor Mutations in Saccharomyces cerevisiae.

  2021cites this paper
• Controlling Kinase Activities by Selective Inhibition of Peptide Substrates.

  2021cites this paper
• The regulation of Saccharomyces cerevisiae Snf1 protein kinase on glucose utilization is in a glucose-dependent manner

  2021cites this paper
• RCO-3 and COL-26 form an external-to-internal module that regulates the dual-affinity glucose transport system in Neurospora crassa

  2020cites this paper
• A novel yeast hybrid modeling framework integrating Boolean and enzyme-constrained networks enables exploration of the interplay between signaling and metabolism

  2020cites this paper
• The Regulatory Role of Key Metabolites in the Control of Cell Signaling

  2020cites this paper
• Modeling and analysis of the macronutrient signaling network in budding yeast

  2020cites this paper
• Spontaneous mutations that confer resistance to 2-deoxyglucose act through Hxk2 and Snf1 pathways to regulate gene expression and HXT endocytosis

  2019cites this paper
• Robustness of Nutrient Signaling Is Maintained by Interconnectivity Between Signal Transduction Pathways

  2019cites this paper
• Comprehensive Analysis of Aspergillus nidulans PKA Phosphorylome Identifies a Novel Mode of CreA Regulation

  2019cites this paper
• GLUCOSE SIGNALING AND TRANSCRIPTIONAL REGULATION OF HEXOSE TRANSPORTERS IN SACCHAROMYCES CEREVISIAE

  2019influential citation
• Glucose Sensing and Regulation in Yeasts

  2019cites this paper
• Antagonism between salicylate and the cAMP signal controls yeast cell survival and growth recovery from quiescence

  2018cites this paper
• Self-Amplifying Pulsatile Protein Dynamics without Positive Feedback.

  2018cites this paper
• Control of nongenetic heterogeneity in growth rate and stress tolerance of Saccharomyces cerevisiae by cyclic AMP-regulated transcription factors

  2018cites this paper
• Conventional and emerging roles of the energy sensor Snf1/AMPK in Saccharomyces cerevisiae

  2018cites this paper
• Coordinated regulation of intracellular pH by two glucose-sensing pathways in yeast

  2017cites this paper
• Coupled feedback loops control the stimulus-dependent dynamics of the yeast transcription factor Msn2

  2017cites this paper
• Sphingolipid accumulation causes mitochondrial dysregulation and cell death

  2017cites this paper
• Regulation of the lignocellulolytic response in filamentous fungi

  2016cites this paper
• Role of Protein Phosphatase Reg2-Glc7 in the Regulation of the Yeast Stress Response Kinase, Snf1

  2016cites this paper
• The Kinome of Edible and Medicinal Fungus Wolfiporia cocos

  2016cites this paper
• Title Regulation of the lignocellulolytic response in filamentous fungi Permalink

  2016cites this paper
• The Hsp 70 homolog Ssb and the 14-3-3 protein Bmh 1 jointly regulate transcription of glucose repressed genes in Saccharomyces cerevisiae

  2016cites this paper
• Signaling N u t r i e n t A vailab ilit y an d S ex

  2016cites this paper
• Age-related changes in AMPK activation: Role for AMPK phosphatases and inhibitory phosphorylation by upstream signaling pathways.

  2016cites this paper
• The eukaryotic protein kinase superfamily of the necrotrophic fungal plant pathogen, Sclerotinia sclerotiorum.

  2016cites this paper
• Hexokinase 2 Is an Intracellular Glucose Sensor of Yeast Cells That Maintains the Structure and Activity of Mig1 Protein Repressor Complex*

  2016cites this paper
• The Hsp70 homolog Ssb and the 14-3-3 protein Bmh1 jointly regulate transcription of glucose repressed genes in Saccharomyces cerevisiae

  2016cites this paper
• Trehalose-6-phosphate synthesis controls yeast gluconeogenesis downstream and independent of SNF1.

  2016cites this paper
• Springing into Action: Reg2 Negatively Regulates Snf1 Protein Kinase and Facilitates Recovery from Prolonged Glucose Starvation in Saccharomyces cerevisiae

  2016cites this paper
• Systems-level investigation of the interaction between glucose metabolism and the Snf1/Mig1 signalling pathway

  2016cites this paper
• Role of Snf1/AMPK as regulator of cell cycle, signal transduction and metabolism in Saccharomyces cerevisiae

  2015influential citation
• Multiple Phosphatases Regulate Carbon Source-Dependent Germination and Primary Metabolism in Aspergillus nidulans

  2015cites this paper
• Cross-Talk between Carbon Metabolism and the DNA Damage Response in S. cerevisiae.

  2015cites this paper
• Molecular communication: crosstalk between the Snf1 and other signaling pathways.

  2015influential citation
• A contribution of budding yeast to unravel aging. Entry into quiescence relies on the transceptor Mtl1 by sensing nutrients and regulation of signaling pathways

  2015cites this paper
• Snf1 Phosphorylates Adenylate Cyclase and Negatively Regulates Protein Kinase A-dependent Transcription in Saccharomyces cerevisiae *

  2015influential citation
• Protein kinase Snf1 is involved in the proper regulation of the unfolded protein response in Saccharomyces cerevisiae.

  2015cites this paper
• Yeast as a model for Ras signalling.

  2014cites this paper
• Glucose- and nitrogen sensing and regulatory mechanisms in Saccharomyces cerevisiae.

  2014cites this paper
• Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae

  2014influential citation
• Glucose Sensing and Signal Transduction in Saccharomyces cerevisiae

  2014cites this paper
• Glucose de‐repression by yeast AMP‐activated protein kinase SNF1 is controlled via at least two independent steps

  2014cites this paper
• Signaling Crosstalk: Integrating Nutrient Availability and Sex

  2013cites this paper
• Prolonged glucose deprivation sensitizes SNF1 to negative regulation by PKA to delay entry into quiescence

  2013influential citation
• Regulation of nuclear tRNA export in response to nutrient stress is not evolutionarily conserved and requires the TORC1 and PKA signaling pathways in Saccharomyces cerevisiae

  2013cites this paper
• Cellular metabolism and its effect on the type iii secretion system of Dickeya dadantii 3937

  2013cites this paper
• Genetic and phenotypic characteristics of baker's yeast: relevance to baking.

  2013influential citation
• Reducing sphingolipid synthesis orchestrates global changes to extend yeast lifespan

  2013cites this paper
• Ligand Binding to the AMP-activated Protein Kinase Active Site Mediates Protection of the Activation Loop from Dephosphorylation*

  2012cites this paper