Quality assessment of drug therapy

C. Daniels

Published 2022 in Atkinson's Principles of Clinical Pharmacology

ABSTRACT

Dozens of new drugs, new combinations, and new dosage forms are approved each year in the USA and Europe. The availability of valuable new agents creates opportunities for improved therapeutic outcomes, but also creates increased opportunities for inappropriate medication use. The clinical pharmacologist must have generalized expertise in the use of medications that can be applied across the organization in clinical practice and in independent and collaborative research activities. Quality assessment and improvement of medication use constitute an important skill set. The objective of this chapter will be to review medication use quality issues in an institutional context and highlight their impact on patient care and clinical research. The focus is on three themes: understanding the medication-use system and organizational interests in medication use; understanding the application of drug-use monitoring as a tool to improve medication use; and understanding processes to identify and improve medication errors. Improvement in quality of medication use revolves around identifying and minimizing systematic risk of error, and improving outcomes through the use of relevant guidelines and benchmarking tools.

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