Clinical Profile of Patients Based on Receptor Status in Carcinoma Breast

Aims & Objectives: The aim of this study is to determine the factors affecting receptor status in carcinoma breast. The objectives include to determine factors to be studied, analyze the clinical and histological factors in relation to receptor status & determine the relation of factors to receptor status Materials and Methods: A prospective time bound study was planned from Nov 2013 to August 2015 with patients getting admitted in Govt Wenlock Hospital, KMC Attavar and KMC-Ambedkar Circle Hospitals in Mangalore. The factors taken into consideration were age, family history, tumour size, lymph node involvement and grading. A ‘p’ value of <0.005 is taken as significant. Results: In a total study of 93 cases, it was noted that patients with tumour size of 2-5cm has a significant correlation with Estrogen receptor (ER) i.e of the 52 patients with tumour size of 2–5cm, 43 patients has ER positive status. p value ( 0.046 ). Out of 54 patients with positive lymph nodal status, 42 patients has HER2 negative status (77.8%). p value ( 0.043). Conclusion: The results of my study implies that lymph node involvement determines the HER2 receptor status and also the tumour size determines the Estrogen receptor (ER) status. However our study could not determine any significant correlation between age and receptor status may be because of sample size being small.

• Publication year

  2016

• Venue

  IOSR Journal of Dental and Medical Sciences

• Publication date

  2016-10-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.9790/0853-1510010813
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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