Nuclear α Spectrin Differentially Affects Monoubiquitinated Versus Non‐Ubiquitinated FANCD2 Function After DNA Interstrand Cross‐Link Damage

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Cellular Biochemistry

• Publication date

  2016-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/jcb.25352PMID 26297932
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Functional Significance of Nuclear α Spectrin

  2015cited by this paper
• FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex

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• XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4.

  2014influential reference
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  2014cited by this paper
• The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder.

  2014cited by this paper
• Non-erythroid alpha spectrin prevents telomere dysfunction after DNA interstrand cross-link damage

  2013cited by this paper
• Fanconi anaemia and the repair of Watson and Crick DNA crosslinks

  2013cited by this paper
• Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase

  2012cited by this paper
• Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway.

  2012cited by this paper
• Fanconi anemia pathway heterogeneity revealed by cisplatin and oxaliplatin treatments.

  2010cited by this paper
• The Fanconi anemia protein, FANCG, binds to the ERCC1-XPF endonuclease via its tetratricopeptide repeats and the central domain of ERCC1.

  2010cited by this paper
• Repair of DNA interstrand cross‐links during S phase of the mammalian cell cycle

  2010cited by this paper
• Several tetratricopeptide repeat (TPR) motifs of FANCG are required for assembly of the BRCA2/D1-D2-G-X3 complex, FANCD2 monoubiquitylation and phleomycin resistance.

  2010influential reference
• Knockdown of mu-calpain in Fanconi anemia, FA-A, cells by siRNA restores alphaII spectrin levels and corrects chromosomal instability and defective DNA interstrand cross-link repair.

  2010cited by this paper
• Translesion DNA synthesis polymerases in DNA interstrand crosslink repair

  2010cited by this paper
• Monoubiquitylation in the Fanconi anemia DNA damage response pathway.

  2009cited by this paper
• The SH3 domain of alphaII spectrin is a target for the Fanconi anemia protein, FANCG.

  2009cited by this paper
• How the fanconi anemia pathway guards the genome.

  2009cited by this paper
• Knockdown of alphaII spectrin in normal human cells by siRNA leads to chromosomal instability and decreased DNA interstrand cross-link repair.

  2009cited by this paper
• The genetic and molecular basis of Fanconi anemia.

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• The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair

  2009cited by this paper
• XPF-ERCC1 Participates in the Fanconi Anemia Pathway of Cross-Link Repair

  2009cited by this paper
• Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights.

  2009cited by this paper
• FANCI Protein Binds to DNA and Interacts with FANCD2 to Recognize Branched Structures

  2009cited by this paper
• The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links

  2009cited by this paper
• Mechanism of replication-coupled DNA interstrand crosslink repair.

  2008influential reference
• FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3

  2008influential reference
• The SH 3 Domain of R II Spectrin Is a Target for the Fanconi Anemia Protein , FANCG †

  2008cited by this paper
• Deficiency in incisions produced by XPF at the site of a DNA interstrand cross-link in Fanconi anemia cells.

  2007cited by this paper
• Histone H2AX and Fanconi anemia FANCD2 function in the same pathway to maintain chromosome stability

  2007cited by this paper
• Emergence of a DNA-damage response network consisting of Fanconi anaemia and BRCA proteins

  2007cited by this paper
• DNA Structure-Induced Recruitment and Activation of the Fanconi Anemia Pathway Protein FANCD2

  2007cited by this paper
• A requirement of FancL and FancD2 monoubiquitination in DNA repair

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  2006cited by this paper
• αII‐Spectrin interacts with five groups of functionally important proteins in the nucleus

  2006cited by this paper
• Regulated interaction of the Fanconi anemia protein, FANCD2, with chromatin.

  2005cited by this paper
• Direct DNA Binding Activity of the Fanconi Anemia D2 Protein*

  2005cited by this paper
• Functional Interaction of Monoubiquitinated FANCD2 and BRCA2/FANCD1 in Chromatin

  2004cited by this paper
• Regulation of the Fanconi anemia pathway by monoubiquitination.

  2003cited by this paper
• Nonerythroid αII spectrin is required for recruitment of FANCA and XPF to nuclear foci induced by DNA interstrand cross-links

  2003cited by this paper
• Fanconi anemia cell lines deficient in alphaII spectrin express normal levels of alphaII spectrin mRNA.

  2003cited by this paper
• Fanconi anemia cell lines deficient in αII spectrin express normal levels of αII spectrin mRNA

  2003cited by this paper
• Human alpha spectrin II and the FANCA, FANCC, and FANCG proteins bind to DNA containing psoralen interstrand cross-links.

  2001cited by this paper
• Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.

  2001influential reference
• Fanconi anemia, complementation group A, cells are defective in ability to produce incisions at sites of psoralen interstrand cross-links.

  2000cited by this paper
• DNA Replication Is Required To Elicit Cellular Responses to Psoralen-Induced DNA Interstrand Cross-Links

  2000cited by this paper
• Human α Spectrin II and the Fanconi Anemia Proteins FANCA and FANCC Interact to Form a Nuclear Complex*

  1999cited by this paper
• Correction of the DNA repair defect in Fanconi anemia complementation groups A and D cells.

  1997cited by this paper
• Human Endonucleolytic Incision of DNA 3′ and 5′ to a Site-directed Psoralen Monoadduct and Interstrand Cross-link (*)

  1995cited by this paper
• Defective DNA endonuclease activities in Fanconi's anemia cells, complementation groups A and B.

  1992cited by this paper

• Critical role of alpha spectrin in DNA repair: the importance of μ-calpain and Fanconi anemia proteins

  2025cites this paper
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• Genome-wide association study of recurrent endometriosis related with ovarian cancer

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• Spectrin and its interacting partners in nuclear structure and function

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• Functions of nuclear actin-binding proteins in human cancer.

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• Nuclear alpha spectrin: Critical roles in DNA interstrand cross-link repair and genomic stability

  2016cites this paper
• Actin, actin-binding proteins, and actin-related proteins in the nucleus

  2016cites this paper
• Coordination of the recruitment of the FANCD2 and PALB2 Fanconi anemia proteins by an ubiquitin signaling network

  2016cites this paper
• MicroRNA-128-3p regulates mitomycin C-induced DNA damage response in lung cancer cells through repressing SPTAN1

  2016cites this paper