The fate of mosaic aneuploid embryos during mouse development.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Developmental Biology

• Publication date

  2006-01-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.YDBIO.2005.11.001PMID 16337934
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• How do so few control so many?

  2005cited by this paper
• Mitotic errors in chromosome 21 of human preimplantation embryos are associated with non-viability.

  2004cited by this paper
• Differences in chromosome susceptibility to aneuploidy and survival to first trimester.

  2004cited by this paper
• Low level chromosome instability in embryonic cells of primary aneuploid mice

  2004cited by this paper
• Transcriptome analysis of human autosomal trisomy.

  2002cited by this paper
• Segregating Sister Genomes: The Molecular Biology of Chromosome Separation

  2002cited by this paper
• Female Germ Cell Aneuploidy and Embryo Death in Mice Lacking the Meiosis-Specific Protein SCP3

  2002cited by this paper
• Sorting Out Chromosome Errors

  2002cited by this paper
• Human genetics and disease: Mechanisms and consequences of somatic mosaicism in humans

  2002cited by this paper
• Chromosome mosaicism in cleavage-stage human embryos: evidence of a maternal age effect.

  2002cited by this paper
• Telomere dysfunction triggers extensive DNA fragmentation and evolution of complex chromosome abnormalities in human malignant tumors

  2001cited by this paper
• Analysis of a malsegregating mouse Y chromosome: evidence that the earliest cleavage divisions of the mammalian embryo are non-disjunction-prone.

  2001cited by this paper
• Developmental ability of chromosomally abnormal human embryos to develop to the blastocyst stage.

  2001cited by this paper
• To err (meiotically) is human: the genesis of human aneuploidy

  2001cited by this paper
• The checkpoint monitoring chromosomal pairing in male meiotic cells is p53-independent

  2001cited by this paper
• Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

  2001cited by this paper
• Chromosome analysis of blastomeres from human embryos by using comparative genomic hybridization.

  2000cited by this paper
• Comprehensive chromosomal analysis of human preimplantation embryos using whole genome amplification and single cell comparative genomic hybridization.

  2000cited by this paper
• A long twentieth century of the cell cycle and beyond.

  2000cited by this paper
• Chromosome analysis of blastomeres from human embryos by using comparative genomic hybridization

  2000cited by this paper
• Hypersensitivity to DNA damage leads to increased apoptosis during early mouse development.

  2000cited by this paper
• Detailed chromosomal and molecular genetic analysis of single cells by whole genome amplification and comparative genomic hybridisation.

  1999cited by this paper
• Mouse autosomal trisomy: two's company, three's a crowd.

  1999cited by this paper
• p53 in embryonic development: maintaining a fine balance

  1999cited by this paper
• Retarded postimplantation development of X0 mouse embryos: impact of the parental origin of the monosomic X chromosome.

  1998cited by this paper
• Chromosome abnormalities in human embryos.

  1998cited by this paper
• Mosaicism in the inner cell mass of human blastocysts.

  1998cited by this paper
• Human aneuploidy: lessons from achiasmate segregation in Drosophila melanogaster

  1998cited by this paper
• Multicolour FISH detects frequent chromosomal mosaicism and chaotic division in normal preimplantation embryos from fertile patients

  1997cited by this paper
• Meiosis in Drosophila: seeing is believing.

  1995cited by this paper
• Chromosome mosaicism in human embryos.

  1994cited by this paper
• Detection of aneuploidy and chromosomal mosaicism in human embryos during preimplantation sex determination by fluorescent in situ hybridisation, (FISH).

  1993cited by this paper
• Confirmation of CVS mosaicism in term placentae and high frequency of intrauterine growth retardation association with confined placental mosaicism

  1991cited by this paper
• Survival of XO mouse fetuses: effect of parental origin of the X chromosome or uterine environment?

  1991cited by this paper
• The lethal(1)TW-6cs mutation of Drosophila melanogaster is a dominant antimorphic allele of nod and is associated with a single base change in the putative ATP-binding domain.

  1991cited by this paper
• Developmental consequences of autosomal aneuploidy in mammals.

  1987cited by this paper
• Autosomal aneuploidy in mice: generation and developmental consequences.

  1986cited by this paper
• Cytogenetics of pregnancy wastage.

  1985cited by this paper
• Mouse monosomies and trisomies as experimental systems for studying mammalian aneuploidy

  1985cited by this paper
• Trisomy in man.

  1984cited by this paper
• Fetal Loss after Implantation: A Prospective Study

  1980cited by this paper
• Gastrulation in the mouse: Growth and regionalization of the epiblast

  1977cited by this paper
• The immediate postimplantation development of tetraploid mouse blastocysts.

  1976cited by this paper
• Systematic approach to the study of trisomy in the mouse. II.

  1975cited by this paper
• Letter: Handicapped families.

  1975cited by this paper
• A meiotic mutant defective in distributive disjunction in Drosophila melanogaster.

  1973cited by this paper
• The Stability of Broken Ends of Chromosomes in Zea Mays.

  1941cited by this paper
• The Production of Homozygous Deficient Tissues with Mutant Characteristics by Means of the Aberrant Mitotic Behavior of Ring-Shaped Chromosomes.

  1938cited by this paper

• Role of spindle assembly checkpoint proteins in gametogenesis and embryogenesis

  2025cites this paper
• The Consequences of DNA Damage in the Early Embryo Are Important for Practical Procedures in Assisted Reproduction

  2025cites this paper
• The mosaic embryo: what it means for the doctor and the patient.

  2023cites this paper
• Human embryo live imaging reveals nuclear DNA shedding during blastocyst expansion and biopsy.

  2023cites this paper
• Preimplantation chromosomal mosaics, chimaeras and confined placental mosaicism

  2022cites this paper
• Maternal selection of human embryos in early gestation: Insights from recurrent miscarriage.

  2022cites this paper
• The Centriole’s Role in Miscarriages

  2022cites this paper
• A pluripotent developmental state confers a low fidelity of chromosome segregation

  2022cites this paper
• Parental genome unification is highly error-prone in mammalian embryos

  2021cites this paper
• From contemplation to classification of chromosomal mosaicism in human preimplantation embryos

  2021cites this paper
• Chromosome segregation error during early cleavage in mouse pre-implantation embryo does not necessarily cause developmental failure after blastocyst stage

  2020cites this paper
• The "life code": a theory that unifies the human life cycle and the origin of human tumors.

  2020cites this paper
• Aneuploidy during the onset of mouse embryo development.

  2020cites this paper
• Aneuploidy and DNA Methylation as Mirrored Features of Early Human Embryo Development

  2020cites this paper
• Germline nuclear transfer in mice may rescue poor embryo development associated with advanced maternal age and early embryo arrest.

  2020cites this paper
• Molecular Contribution to Embryonic Aneuploidy and Genotypic Complexity During Initial Cleavage Divisions of Mammalian Development

  2020cites this paper
• Parental genome unification is highly erroneous in mammalian embryos

  2020cites this paper
• Cell-Size-Independent Spindle Checkpoint Failure Underlies Chromosome Segregation Error in Mouse Embryos.

  2019cites this paper
• Defining the Transcriptional and Epigenetic Signature of Mouse Embryonic Stem Cells with Compromised Developmental Potency

  2019cites this paper
• Differences in blastomere totipotency in 2-cell mouse embryos are a maternal trait mediated by asymmetric mRNA distribution

  2019cites this paper
• Causes and consequences of chromosome segregation error in preimplantation embryos.

  2018cites this paper
• Regulatory mechanisms and biological implications of protein complex assembly

  2018cites this paper
• A speculative outlook on embryonic aneuploidy: Can molecular pathways be involved?

  2018cites this paper
• Ablating ATR in mouse meiosis and its consequences for synapsis, recombination and meiotic surveillance mechanisms

  2018cites this paper
• Unravelling chromosomal instability in mammalian preimplantation embryos using single-cell genomics

  2018cites this paper
• Chromosomal analysis in IVF: just how useful is it?

  2018cites this paper
• Single-cell sequencing of primate preimplantation embryos reveals chromosome elimination via cellular fragmentation and blastomere exclusion

  2018cites this paper
• Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potential

  2016cites this paper
• Blastocysts derivation from somatic cell fusion with premature oocytes (prematuration somatic cell fusion)

  2016cites this paper
• Micronucleus formation causes perpetual unilateral chromosome inheritance in mouse embryos

  2016cites this paper
• The adverse outcome pathway (AOP) for chemical binding to tubulin in oocytes leading to aneuploid offspring

  2016cites this paper
• Mammalian pre-implantation chromosomal instability: species comparison, evolutionary considerations, and pathological correlations

  2015influential citation
• Preimplantation Embryo Development and Primordial Germ Cell Lineage Specification

  2015cites this paper
• Chromosomal instability in mammalian pre-implantation embryos: potential causes, detection methods, and clinical consequences

  2015cites this paper
• The Majority of Resorptions in Old Mice Are Euploid

  2015cites this paper
• Blastocentesis: a source of DNA for preimplantation genetic testing. Results from a pilot study.

  2014cites this paper
• Merotelic attachments allow alignment and stabilization of chromatids in meiosis II oocytes

  2014cites this paper
• Array comparative genomic hybridization analyses of all blastomeres of a cohort of embryos from young IVF patients revealed significant contribution of mitotic errors to embryo mosaicism at the cleavage stage

  2014cites this paper
• Comparison of epigenetic mediator expression and function in mouse and human embryonic blastomeres

  2014cites this paper
• A non-canonical mode of microtubule organization operates throughout pre-implantation development in mouse

  2013cites this paper
• Improving embryo quality in assisted reproduction

  2013cites this paper
• Nuclear Reprogramming: Kinetics of Cell Cycle and Metabolic Progression as Determinants of Success

  2012cites this paper
• Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage

  2012cites this paper
• Abnormal chromosome segregation at early cleavage is a major cause of the full-term developmental failure of mouse clones.

  2012cites this paper
• Molecular origin of mitotic aneuploidies in preimplantation embryos.

  2012cites this paper
• Preimplantation genetic screening: does it help or hinder IVF treatment and what is the role of the embryo?

  2011cites this paper
• Aneuploidy in the Human Cleavage Stage Embryo

  2011cites this paper
• Chromosome 12q24.31-q24.33 deletion causes multiple dysmorphic features and developmental delay: First mosaic patient and overview of the phenotype related to 12q24qter defects

  2011cites this paper
• Preclinical validation of a microarray method for full molecular karyotyping of blastomeres in a 24-h protocol

  2010cites this paper
• A novel mammalian HORMA domain-containing protein, HORMAD1, preferentially associates with unsynapsed meiotic chromosomes.

  2010cites this paper
• Increased incidence of mosaicism detected by FISH in murine blastocyst cultured in vitro.

  2010cites this paper
• Genetic analysis of postzygotic hybridisation barriers in Arabidopsis thaliana

  2010cites this paper
• Redefining endometrial receptivity.

  2010cites this paper
• What next for preimplantation genetic screening? Beyond aneuploidy.

  2009cites this paper
• Chromosomal mosaicism in mouse two-cell embryos after paternal exposure to acrylamide.

  2009cites this paper
• Assessment of chromosomal integrity using a novel live-cell imaging technique in mouse embryos produced by intracytoplasmic sperm injection.

  2009cites this paper
• Effects of modification of in vitro fertilization techniques on the sex ratio of the resultant bovine embryos.

  2008cites this paper
• Disruption of pairing and synapsis of chromosomes causes stage-specific apoptosis of male meiotic cells.

  2008cites this paper
• Evaluation of the developmental competence and chromosomal compliment of mouse oocytes derived from in-vitro growth and maturation of preantral follicles

  2008cites this paper
• Progression of meiotic recombination requires structural maturation of the central element of the synaptonemal complex

  2008cites this paper
• Global gene expression analysis of bovine blastocysts produced by multiple methods

  2008cites this paper
• Molecular cytogenetic investigation of the origin of chromosomal abnormalities arising in human preimplantation embryos and oocytes.

  2008cites this paper
• Oocyte karyotyping by comparative genomic hybridization [correction of hybrydization] provides a highly reliable method for selecting "competent" embryos, markedly improving in vitro fertilization outcome: a multiphase study.

  2007cites this paper
• Milder ovarian stimulation for in-vitro fertilization reduces aneuploidy in the human preimplantation embryo: a randomized controlled trial.

  2007cites this paper
• Use of cross-species in-situ hybridization (ZOO-FISH) to assess chromosome abnormalities in day-6 in-vivo- or in-vitro-produced sheep embryos

  2007cites this paper
• Expression and functional analyses of murine Pelota (Pelo) gene

  2007cites this paper
• Effets de la stimulation sur la qualité ovocytaire

  2007cites this paper
• [Consequences of stimulation on oocyte quality].

  2007cites this paper
• A haploid-diploid-triploid mosaic of the Amazon molly, Poecilia formosa

  2007cites this paper
• Meiosis 2007 – Where have we got to and where are we going?

  2007cites this paper
• Bi-orientation of achiasmatic chromosomes in meiosis I oocytes contributes to aneuploidy in mice

  2007cites this paper
• Oocyte karyotyping by comparative genomic hybrydization provides a highly reliable method for selecting “competent” embryos, markedly improving in vitro fertilization outcome: a multiphase study

  2007cites this paper
• Chromosome stability differs in cloned mouse embryos and derivative ES cells.

  2007cites this paper
• Characterization of a novel meiosis-specific protein within the central element of the synaptonemal complex

  2006cites this paper
• Mouse Embryonic Stem Cells Form Follicle‐Like Ovarian Structures but Do Not Progress Through Meiosis

  2006cites this paper