Activin A: autocrine regulator of kidney development and repair.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Endocrine journal

• Publication date

  2008-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1507/ENDOCRJ.KR-113PMID 17827789
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Activin A is an endogenous inhibitor of ureteric bud outgrowth from the Wolffian duct.

  2006cited by this paper
• Roles of activin in tissue repair, fibrosis, and inflammatory disease.

  2006cited by this paper
• The cellular basis of kidney development.

  2006cited by this paper
• Update on mechanisms of ischemic acute kidney injury.

  2006cited by this paper
• Activin Signaling and Its Role in Regulation of Cell Proliferation, Apoptosis, and Carcinogenesis

  2006cited by this paper
• Glomerular activin A overexpression is linked to fibrosis in anti-Thy1 glomerulonephritis.

  2005cited by this paper
• MEKK1 Transduces Activin Signals in Keratinocytes To Induce Actin Stress Fiber Formation and Migration

  2005cited by this paper
• The role of GDNF/Ret signaling in ureteric bud cell fate and branching morphogenesis.

  2005cited by this paper
• Branching morphogenesis and kidney disease

  2004cited by this paper
• Activin a in the regulation of corneal neovascularization and vascular endothelial growth factor expression.

  2004cited by this paper
• New insights into TGF-β–Smad signalling

  2004cited by this paper
• Novel factors in regulation of activin signaling.

  2004cited by this paper
• Activin A is a potent activator of renal interstitial fibroblasts.

  2004cited by this paper
• Defining the epithelial stem cell niche in skin.

  2004cited by this paper
• New insights into TGF-beta-Smad signalling.

  2004cited by this paper
• TGF-beta superfamily members modulate growth, branching, shaping, and patterning of the ureteric bud.

  2004cited by this paper
• Crucial role of activin a in tubulogenesis of endothelial cells induced by vascular endothelial growth factor.

  2004cited by this paper
• Defining the Epithelial Stem Cell Niche in Skin

  2004cited by this paper
• Activin A and follistatin in systemic inflammation.

  2004cited by this paper
• Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo.

  2003cited by this paper
• Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus

  2003cited by this paper
• Mechanisms of TGF-beta signaling from cell membrane to the nucleus.

  2003cited by this paper
• Recent advances in the pathophysiology of ischemic acute renal failure.

  2003cited by this paper
• Activin a produced by ureteric bud is a differentiation factor for metanephric mesenchyme.

  2003cited by this paper
• Genetic Analysis of the Mammalian Transforming Growth Factor-β Superfamily

  2002cited by this paper
• Involvement of Pax-2 in the action of activin A on tubular cell regeneration.

  2002cited by this paper
• Genetic analysis of the mammalian transforming growth factor-beta superfamily.

  2002cited by this paper
• Activins, Inhibins, and Follistatins: From Endocrinology to Signaling. A Paradigm for the New Millennium

  2002cited by this paper
• Paradigm shift from classic anatomic theories to contemporary cell biological views of CAKUT.

  2002cited by this paper
• Little Evidence for Developmental Plasticity of Adult Hematopoietic Stem Cells

  2002cited by this paper
• Activin A: an autocrine regulator of cell growth and differentiation in renal proximal tubular cells.

  2002cited by this paper
• Toward an etiological classification of developmental disorders of the kidney and upper urinary tract.

  2002cited by this paper
• Up-regulation of the expression of activins in the pancreatic duct by reduction of the beta-cell mass.

  2002cited by this paper
• The p38 MAPK Pathway Is Required for Cell Growth Inhibition of Human Breast Cancer Cells in Response to Activin*

  2001cited by this paper
• Role of the activin-follistatin system in the morphogenesis and regeneration of the renal tubules.

  2001cited by this paper
• The role of the activin-follistatin system in the developmental and regeneration processes of the kidney.

  2001cited by this paper
• Follistatin-related protein (FSRP): a new member of the follistatin gene family.

  2001cited by this paper
• Activins as regulators of branching morphogenesis.

  2001cited by this paper
• Involvement of the activin-follistatin system in tubular regeneration after renal ischemia in rats.

  2001cited by this paper
• Hepatocyte growth factor induces branching tubulogenesis in MDCK cells by modulating the activin-follistatin system.

  2000cited by this paper
• Number of glomeruli is increased in the kidney of transgenic mice expressing the truncated type II activin receptor.

  2000cited by this paper
• The role of activin and transforming growth factor‐β in the regulation of organ mass in the rat liver

  2000cited by this paper
• Silencing of TGF-beta signalling by the pseudoreceptor BAMBI.

  1999cited by this paper
• Re-expression of the developmental gene Pax-2 during experimental acute tubular necrosis in mice 1.

  1999cited by this paper
• A Novel Role of Follistatin, an Activin-binding Protein, in the Inhibition of Activin Action in Rat Pituitary Cells

  1997cited by this paper
• The PAX2 tanscription factor is expressed in cystic and hyperproliferative dysplastic epithelia in human kidney malformations.

  1996cited by this paper
• Follistatins and alpha 2-macroglobulin are soluble binding proteins for inhibin and activin.

  1996cited by this paper
• Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells.

  1996cited by this paper
• Follistatins and α2-Macroglobulin Are Soluble Binding Proteins for Inhibin and Activin

  1996cited by this paper
• Molecular cloning of the mouse activin beta E subunit gene.

  1996cited by this paper
• Cloning of a new member of the TGF-beta family: a putative new activin beta C chain.

  1995cited by this paper
• A single intraportal administration of follistatin accelerates liver regeneration in partially hepatectomized rats.

  1995cited by this paper
• Pax-2 controls multiple steps of urogenital development.

  1995cited by this paper
• Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse.

  1995cited by this paper
• Cloning of a New Member of the TGF-β Family: A Putative New Activin βC Chain

  1995cited by this paper
• Molecular cloning and functional analysis of a new activin beta subunit: a dorsal mesoderm-inducing activity in Xenopus.

  1995cited by this paper
• Localization of proliferating cell nuclear antigen, vimentin, c-Fos, and clusterin in the postischemic kidney. Evidence for a heterogenous genetic response among nephron segments, and a large pool of mitotically active and dedifferentiated cells.

  1994cited by this paper
• Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities

  1993cited by this paper
• Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor.

  1991influential reference
• Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors.

  1991cited by this paper
• Follistatin binds to both activin and inhibin through the common subunit.

  1991cited by this paper
• Immunohistochemical localization of follistatin in rat tissues.

  1991cited by this paper
• Follistatin, an activin-binding protein, associates with heparan sulfate chains of proteoglycans on follicular granulosa cells.

  1991cited by this paper
• FOLLISTATIN BINDS TO BOTH ACTIVIN AND INHIBIN THROUGH THE COMMON BETA-SUBUNIT

  1991cited by this paper
• Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures.

  1990cited by this paper
• Activin-binding protein from rat ovary is follistatin.

  1990cited by this paper
• Activin-like factor from a Xenopus laevis cell line responsible for mesoderm induction

  1990cited by this paper
• Activin is a nerve cell survival molecule

  1990cited by this paper
• Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A

  1990cited by this paper
• Erythroid differentiation factor is encoded by the same mRNA as that of the inhibin beta A chain.

  1988cited by this paper
• Organogenesis of the kidney

  1987cited by this paper
• Isolation and partial characterization of follistatin: a single-chain Mr 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone.

  1987cited by this paper
• Pituitary FSH is released by a heterodimer of the β-subunits from the two forms of inhibin

  1986cited by this paper
• Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid

  1986cited by this paper

• Evaluation of Urinary Activin A in different stages of AKI

  2024cites this paper
• The activin-follistatin system: Key regulator of kidney development, regeneration, inflammation, and fibrosis.

  2024cites this paper
• Immunostaining of βA-Activin and Follistatin Is Decreased in HPV(+) Cervical Pre-Neoplastic and Neoplastic Lesions

  2023cites this paper
• Tubule-Derived Follistatin Is Increased in the Urine of Rats with Renal Ischemia and Reflects the Severity of Acute Tubular Damage

  2023cites this paper
• Diminished vasculogenesis under inflammatory conditions is mediated by Activin A

  2023cites this paper
• Effect of NAD+ boosting on kidney ischemia-reperfusion injury

  2021cites this paper
• [Involvement of Notch1 and ALK4/5 Signaling Pathways in Renal Tubular Cell Death: Their Application to Clarification of Cadmium Toxicity].

  2020cites this paper
• Fibrodysplasia Ossificans Progressiva (FOP): A Segmental Progeroid Syndrome

  2020cites this paper
• Urinary Activin A is a novel biomarker reflecting renal inflammation and tubular damage in ANCA-associated vasculitis

  2019cites this paper
• Human Epicardial Adipose Tissue Activin A Expression Predicts Occurrence of Postoperative Atrial Fibrillation in Patients Receiving Cardiac Surgery.

  2019cites this paper
• Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms

  2019cites this paper
• Activin A: a novel urinary biomarker of renal impairment in multiple myeloma

  2019cites this paper
• Activin A　- A Potentially Useful Biomarker of Diastolic Dysfunction.

  2019cites this paper
• Circadian rhythm of activin A and related parameters of mineral metabolism in normal and uremic rats

  2019cites this paper
• 3D Co-Culture with Vascular Cells Supports Long-Term Hepatocyte Phenotype and Function In Vitro

  2018cites this paper
• LncRNA MALAT1 modified progression of clear cell kidney carcinoma (KIRC) by regulation of miR‐194‐5p/ACVR2B signaling

  2018cites this paper
• Identification of Urinary Activin A as a Novel Biomarker Reflecting the Severity of Acute Kidney Injury

  2018cites this paper
• Clinical Regenerative Medicine in Urology

  2017cites this paper
• Activin A in Inflammation, Tissue Repair, and Fibrosis: Possible Role as Inflammatory and Fibrotic Mediator of Uterine Fibroid Development and Growth

  2017cites this paper
• Involvement of infiltrating macrophage-derived activin A in the progression of renal damage in MRL-lpr mice.

  2017cites this paper
• Ligand trap for the activin type IIA receptor protects against vascular disease and renal fibrosis in mice with chronic kidney disease.

  2016cites this paper
• Activin A expression in esophageal carcinoma and its association with tumor aggressiveness and differentiation.

  2015cites this paper
• Activin A: Its Role and Involvement in Inflammatory Diseases

  2015cites this paper
• Activin A induction of erythroid differentiation sensitizes K562 chronic myeloid leukemia cells to a subtoxic concentration of imatinib.

  2014cites this paper
• Follistatin, an Activin Antagonist, Ameliorates Renal Interstitial Fibrosis in a Rat Model of Unilateral Ureteral Obstruction

  2014cites this paper
• Regenerative Medicine for the Kidney: Renotropic Factors, Renal Stem/Progenitor Cells, and Stem Cell Therapy

  2014cites this paper
• Antagonists of bone morphogenetic proteins in kidney disease.

  2010cites this paper
• Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-β signaling

  2010cites this paper
• Die Bedeutung von Zytokinen der TGF-β Familie für die Differenzierung von T-Zellen

  2009cites this paper
• Inhibin betaB expression in murine adipose tissue and its regulation by leptin, insulin and dexamethasone.

  2009cites this paper
• The role of the Lim1 gene in vertebrate kidney development

  2008cites this paper
• Peroxisome Proliferator-activated Receptor γ Down-regulates Follistatin in Intestinal Epithelial Cells through SP1*

  2008cites this paper