Pyrrolidinedithiocarbamate Induces Apoptosis in Human Acute Myelogenous Leukemic Cells Affecting NF-κB Activity

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Cancer Investigation

• Publication date

  2005-01-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1081/CNV-67147
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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  1999influential reference
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  1998influential reference
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  1995influential reference
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