A two‐domain model for the R domain of the cystic fibrosis transmembrane conductance regulator based on sequence similarities

No abstract is available for this paper.

• Publication year

  1994

• Venue

  FEBS Letters

• Publication date

  1994-04-25

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0014-5793(94)80300-5PMID 7513286
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Knowledge‐based model building of proteins: Concepts and examples

  1993cited by this paper
• Progress in protein structure prediction?

  1993cited by this paper
• Comparison of conformational characteristics in structurally similar protein pairs

  1993cited by this paper
• Regulation of the cystic fibrosis transmembrane conductance regulator Cl- channel by specific protein kinases and protein phosphatases.

  1993cited by this paper
• Protein kinase A (PKA) still activates CFTR chloride channel after mutagenesis of all 10 PKA consensus phosphorylation sites.

  1993cited by this paper
• Genomic organization and expression of simian foamy virus type 3 (SFV-3).

  1992cited by this paper
• Phosphorylation of the cystic fibrosis transmembrane conductance regulator.

  1992cited by this paper
• Identification and developmental expression of the Xenopus laevis cystic fibrosis transmembrane conductance regulator gene.

  1992cited by this paper
• Localization of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) in the rat to chromosome 4 and implications for the evolution of mammalian chromosomes.

  1992cited by this paper
• Purification and functional reconstitution of the cystic fibrosis transmembrane conductance regulator (CFTR).

  1992cited by this paper
• ABC transporters: from microorganisms to man.

  1992cited by this paper
• Identification and localization of a dogfish homolog of human cystic fibrosis transmembrane conductance regulator.

  1991cited by this paper
• A cross-species analysis of the cystic fibrosis transmembrane conductance regulator. Potential functional domains and regulatory sites.

  1991cited by this paper
• Database of homology‐derived protein structures and the structural meaning of sequence alignment

  1991cited by this paper
• Effect of deleting the R domain on CFTR-generated chloride channels.

  1991cited by this paper
• Cloning the mouse homolog of the human cystic fibrosis transmembrane conductance regulator gene.

  1991cited by this paper
• Phosphorylation of the R domain by cAMP-dependent protein kinase regulates the CFTR chloride channel.

  1991cited by this paper
• Phosphorylation-regulated CI− channel in CHO cells stably expressing the cystic fibrosis gene

  1991cited by this paper
• The complete nucleotide sequence of pea seed-borne mosaic virus RNA.

  1991cited by this paper
• Completion of the genomic sequence of the simian rotavirus SA11: nucleotide sequences of segments 1, 2, and 3.

  1990cited by this paper
• Rapid and sensitive sequence comparison with FASTP and FASTA.

  1990cited by this paper
• Comparative analysis of the retroviral pol and env protein sequences reveal different evolutionary trees

  1990cited by this paper
• Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells

  1990cited by this paper
• Identification of the cystic fibrosis gene: chromosome walking and jumping.

  1989cited by this paper
• Origins and Evolutionary Relationships of Retroviruses

  1989cited by this paper
• Nucleotide sequence of bovine rotavirus gene 1 and expression of the gene product in Baculovirus

  1989cited by this paper
• Nucleotide sequence of HIV1-NDK: a highly cytopathic strain of the human immunodeficiency virus.

  1989cited by this paper
• Nucleotide sequence of gene segment 1 of a porcine rotavirus strain.

  1989cited by this paper
• Genetic organization of gibbon ape leukemia virus.

  1989cited by this paper
• Nucleotide sequence of potato virus Y (N Strain) genomic RNA.

  1989cited by this paper
• Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA.

  1989cited by this paper
• Improved tools for biological sequence comparison.

  1988cited by this paper
• Nucleotide sequence of dengue 2 RNA and comparison of the encoded proteins with those of other flaviviruses.

  1988cited by this paper
• Analysis of the primary structure of the long terminal repeat and the gag and pol genes of the human spumaretrovirus

  1988cited by this paper
• Sequence of simian immunodeficiency virus from macaque and its relationship to other human and simian retroviruses

  1987cited by this paper
• Chloride and potassium channels in cystic fibrosis airway epithelia

  1986cited by this paper
• Computer analysis ofretroviral poigenes: Assignment ofenzymatic functions tospecific sequences andhomologies with nonviral enzymes

  1986cited by this paper
• Nucleotide sequence of the visna lentivirus: relationship to the AIDS virus.

  1985cited by this paper
• Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution.

  1985cited by this paper
• Three-dimensional structure of membrane and surface proteins.

  1984cited by this paper
• Chloride impermeability in cystic fibrosis

  1983cited by this paper
• Nucleotide sequence of the simian sarcoma virus genome: demonstration that its acquired cellular sequences encode the transforming gene product p28sis.

  1983cited by this paper
• Sequence homology between retroviral reverse transcriptase and putative polymerases of hepatitis B virus and cauliflower mosaic virus

  1983cited by this paper
• Similar amino acid sequences: chance or common ancestry?

  1981cited by this paper
• Nucleotide sequence of Moloney murine leukaemia virus

  1981cited by this paper

• The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue

  2021cites this paper
• Insights into the Interactions between CFTR and Small Molecule Modulators

  2014cites this paper
• Structural changes of CFTR R region upon phosphorylation: a plastic platform for intramolecular and intermolecular interactions

  2013cites this paper
• 6.6 Structures and Mechanisms in Chloride Channels

  2012cites this paper
• Role of individual R domain phosphorylation sites in CFTR regulation by protein kinase A.

  2009cites this paper
• CFTR function and prospects for therapy.

  2008cites this paper
• Molecular basis for the ATPase activity of CFTR.

  2008cites this paper
• Solubilizing mutations used to crystallize one CFTR domain attenuate the trafficking and channel defects caused by the major cystic fibrosis mutation.

  2008cites this paper
• Rôles des interactions interdomaines dans le comportement cellulaire de la protéine CFTR

  2008cites this paper
• PKC phosphorylation modulates PKA-dependent binding of the R domain to other domains of CFTR.

  2008cites this paper
• Cystic Fibrosis Transmembrane Conductance Regulator Sequences: Comparative Analysis

  2006cites this paper
• Search for proteins with similarity to the CFTR R domain using an optimized RDBMS solution, mBioSQL

  2006influential citation
• The effects of dietary sodium loading on the activity and expression of Na, K-ATPase in the rectal gland of the European dogfish (Scyliorhinus canicula).

  2002cites this paper
• Overexpression and characterization of the cystic fibrosis protein CFTR using AFM and MALDI-TOF-MS

  2002cites this paper
• The C-terminal part of the R-domain, but not the PDZ binding motif, of CFTR is involved in interaction with Ca2+-activated Cl– channels

  2001cites this paper
• Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channel by Its R Domain*

  2001cites this paper
• Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channels with R Domain Deletions and Translocations Show Phosphorylation-dependent and -independent Activity*

  2001cites this paper
• R-domain interactions with distal regions of CFTR lead to phosphorylation and activation.

  2000cites this paper
• Definition of a "functional R domain" of the cystic fibrosis transmembrane conductance regulator.

  2000cites this paper
• A functional R domain from cystic fibrosis transmembrane conductance regulator is predominantly unstructured in solution.

  2000cites this paper
• Nucleotide-binding domain 1 of cystic fibrosis transmembrane conductance regulator production of a suitable protein for structural studies.

  2000cites this paper
• Functional dissection of the R domain of cystic fibrosis transmembrane conductance regulator 1

  1999cites this paper
• Functional Domain Analysis of the Yeast ABC Transporter Ycf1p by Site-directed Mutagenesis*

  1999cites this paper
• Structure and function of the CFTR chloride channel.

  1999cites this paper
• What we know and what we do not know about cystic fibrosis transmembrane conductance regulator.

  1998cites this paper
• A Conserved Region of the R Domain of Cystic Fibrosis Transmembrane Conductance Regulator Is Important in Processing and Function*

  1998cites this paper
• Characterization of 19 disease-associated missense mutations in the regulatory domain of the cystic fibrosis transmembrane conductance regulator.

  1998cites this paper
• Covalent Modification of the Regulatory Domain Irreversibly Stimulates Cystic Fibrosis Transmembrane Conductance Regulator*

  1997cites this paper
• A platform-independent graphical user interface for SEQSEE and XALIGN

  1997cites this paper
• Function of the R Domain in the Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channel*

  1997cites this paper
• Expression in Escherichia coli of cytoplasmic portions of the cystic fibrosis transmembrane conductance regulator: apparent bacterial toxicity of peptides containing R-domain sequences.

  1996cites this paper
• A recombinant peptide model of the first nucleotide‐binding fold of the cystic fibrosis transmembrane conductance regulator: Comparison of wild‐type and ΔF508 mutant forms

  1996cites this paper
• Mutation of potential phosphorylation sites in the recombinant R domain of the cystic fibrosis transmembrane conductance regulator has significant effects on domain conformation.

  1995cites this paper
• The molecular basis of chloride transport in shark rectal gland.

  1994cites this paper