Serine protease activity of Per a 10 augments allergen‐induced airway inflammation in a mouse model

No abstract is available for this paper.

• Publication year

  2009

• Venue

  European Journal of Clinical Investigation

• Publication date

  2009-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/j.1365-2362.2009.02112.xPMID 19397689
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Identification of a serine protease as a major allergen (Per a 10) of Periplaneta americana

  2008cited by this paper
• Biopotency and identification of allergenic proteins in Periplaneta americana extract for clinical applications.

  2007cited by this paper
• Cockroach allergen biology and mitigation in the indoor environment.

  2007cited by this paper
• Role of Breast Milk in a Mouse Model of Maternal Transmission of Asthma Susceptibility

  2007cited by this paper
• Proteases as Th2 adjuvants

  2007cited by this paper
• Effect of choline chloride in allergen-induced mouse model of airway inflammation

  2007cited by this paper
• Role of Breast Milk in a Mouse Model of Maternal Transmission of Asthma Susceptibility1

  2006cited by this paper
• Crucial Commitment of Proteolytic Activity of a Purified Recombinant Major House Dust Mite Allergen Der p1 to Sensitization toward IgE and IgG Responses1

  2006cited by this paper
• Allergenicity assessment of transgenic mustard (Brassica juncea) expressing bacterial codA gene

  2006cited by this paper
• Pen ch 13 allergen induces secretion of mediators and degradation of occludin protein of human lung epithelial cells

  2006cited by this paper
• Cockroach allergen Bla g 2: an unusual aspartic proteinase.

  2005cited by this paper
• Cockroach allergen extract stimulates protease-activated receptor-2 (PAR-2) expressed in mouse lung fibroblast

  2004cited by this paper
• Characterization of Exposure to Low Levels of Viable Penicillium chrysogenum Conidia and Allergic Sensitization Induced by a Protease Allergen Extract from Viable P. chrysogenum Conidia in Mice

  2003cited by this paper
• Proteolytic activity of the house dust mite allergen Der p 1 enhances allergenicity in a mouse inhalation model

  2003cited by this paper
• German cockroach extract increases bronchial epithelial cell interleukin‐8 expression

  2003cited by this paper
• Alkaline Serine Proteinase from Aspergillus fumigatus Has Synergistic Effects on Asp-f-2-Induced Immune Response in Mice

  2002cited by this paper
• A Protease-Activated Pathway Underlying Th Cell Type 2 Activation and Allergic Lung Disease1

  2002cited by this paper
• Intrinsic properties of allergens and environmental exposure as determinants of allergenicity *

  2002cited by this paper
• Purified recombinant A. fumigatus allergens induce different responses in mice.

  2001cited by this paper
• Temporal association between airway hyperresponsiveness and airway eosinophilia in ovalbumin-sensitized mice.

  2001cited by this paper
• The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from faecal pellets of Dermatophagoides pteronyssinus

  2001cited by this paper
• Peptidase allergens, occludin and claudins. Do their interactions facilitate the development of hypersensitivity reactions at mucosal surfaces?

  2001cited by this paper
• Cockroach Allergen-Induced Eosinophilic Airway Inflammation in HLA-DQ/Human CD4+ Transgenic Mice1

  2001cited by this paper
• Trypsin Induces Activation and Inflammatory Mediator Release from Human Eosinophils Through Protease-Activated Receptor-21

  2001cited by this paper
• The proteolytic activity of the major dust mite allergen Der p 1 enhances the IgE antibody response to a bystander antigen

  2001cited by this paper
• Cutting Edge: The Absence of C3 Demonstrates a Role for Complement in Th2 Effector Functions in a Murine Model of Pulmonary Allergy1

  2001cited by this paper
• Interleukin-8 secretion and neutrophil recruitment accompanies induced sputum eosinophil activation in children with acute asthma.

  2000cited by this paper
• Murine Allergic Respiratory Responses to the Major House Dust Mite Allergen Der p 1

  1999cited by this paper
• The immunopathology of extrinsic (atopic) and intrinsic (non-atopic) asthma: more similarities than differences.

  1999cited by this paper
• A mite subversive: cleavage of CD23 and CD25 by Der p 1 enhances allergenicity.

  1998cited by this paper
• Temporal role of chemokines in a murine model of cockroach allergen-induced airway hyperreactivity and eosinophilia.

  1998cited by this paper
• A dose-response relationship between exposure to cockroach allergens and induction of sensitization in an experimental asthma in Hartley guinea pigs.

  1998cited by this paper
• Generation of anaphylatoxins through proteolytic processing of C3 and C5 by house dust mite protease.

  1997cited by this paper
• Kinetics and quantitation of eosinophil and neutrophil recruitment to allergic lung inflammation in a brown Norway rat model.

  1997cited by this paper
• Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

  1996cited by this paper
• Antigen-mediated pulmonary eosinophilia in immunoglobulin G1-sensitized guinea pigs: eosinophil peroxidase as a simple specific marker for detecting eosinophils in bronchoalveolar lavage fluid.

  1993cited by this paper
• Interleukin-5, eosinophils, and disease.

  1992cited by this paper
• IL-4 directs the development of Th2-like helper effectors.

  1990cited by this paper
• IL-4 is required to generate and sustain in vivo IgE responses.

  1988cited by this paper

• Flagellin conjugated Per a 10 and its T cell peptides attenuate airway inflammation and restore cellular function

  2024cites this paper
• Airborne indoor allergen serine proteases and their contribution to sensitisation and activation of innate immunity in allergic airway disease

  2024cites this paper
• The New Paradigm: The Role of Proteins and Triggers in the Evolution of Allergic Asthma

  2024cites this paper
• Protease allergens as initiators–regulators of allergic inflammation

  2023cites this paper
• Sensing of protease activity as a triggering mechanism of Th2 cell immunity and allergic disease

  2023cites this paper
• Periplaneta americana (Insecta: Blattodea) and organ fibrosis: A mini review

  2022cites this paper
• Identification of Per a 13 as a novel allergen in American cockroach.

  2022cites this paper
• Cockroaches: Allergens, Component-resolved Diagnosis (CRD) and Component-resolved Immunotherapy.

  2020cites this paper
• A Novel Serine Protease Inhibitor PE-BBI Ameliorates Cockroach Extract-Mediated Airway Epithelial Barrier Dysfunction

  2020cites this paper
• Airway Mycosis and the Regulation of Type 2 Immunity

  2020cites this paper
• Benefits of antifungal therapy in asthma patients with airway mycosis: A retrospective cohort analysis

  2018cites this paper
• Serine protease allergen favours Th2 responses via PAR‐2 and STAT3 activation in murine model

  2018cites this paper
• Cockroach protease allergen induces allergic airway inflammation via epithelial cell activation

  2017cites this paper
• Role of proteases in pathophysiology of allergic diseases

  2016cites this paper
• PI3K and ERK1/2 kinase inhibition potentiate protease inhibitor to attenuate allergen induced Th2 immune response in mouse.

  2016cites this paper
• Immunogenic peptides: B & T Cell Epitopes of Per a 10 Allergen of Periplaneta americana.

  2016cites this paper
• Protease activity of Per a 10 potentiates Th2 polarization by increasing IL‐23 and OX40L

  2015cites this paper
• Per a 10 protease activity modulates CD40 expression on dendritic cell surface by nuclear factor‐kappaB pathway

  2015cites this paper
• DC type 2 polarization depends on both the allergic status of the individual and protease activity of Per a 10.

  2015cites this paper
• Per a 10 activates human derived epithelial cell line in a protease dependent manner via PAR-2.

  2015cites this paper
• A cockroach derived serine protease allergen activates airway epithelial cells via PAR2 receptors

  2015cites this paper
• Cockroach Allergy , Respiratory Allergic Diseases and Its Immunotherapy

  2015cites this paper
• Recombinant Allergens for Diagnosis of Cockroach Allergy

  2014cites this paper
• Protease Inhibitor Reduces Airway Response and Underlying Inflammation in Cockroach Allergen-Induced Murine Model

  2014cites this paper
• Investigating cockroach allergens: aiming to improve diagnosis and treatment of cockroach allergic patients.

  2014cites this paper
• MECANISMOS ENVOLVIDOS NA INDUÇÃO DA INFLAMAÇÃO ALÉRGICA PULMONAR PELA SERINO PROTEASE SUBTILISINA

  2014cites this paper
• Role of Allergen Source-Derived Proteases in Sensitization via Airway Epithelial Cells

  2014cites this paper
• Cockroach Allergy, Respiratory Allergic Diseases and Its Immunotherapy

  2014cites this paper
• Efficacy of Recombinant Allergens for Diagnosis of Cockroach Allergy in Patients with Asthma and/or Rhinitis

  2013cites this paper
• Computerized analysis of the relationship between allergenicity of microorganisms and their habitats

  2013cites this paper
• The Longevity of Th2 Humoral Response Induced by Proteases Natterins Requires the Participation of Long-Lasting Innate-Like B Cells and Plasma Cells in Spleen

  2013cites this paper
• Role of Cockroach Proteases in Allergic Disease

  2012cites this paper
• Mechanisms Underlying the Immune Response to Inhaled House Dust Mite

  2012cites this paper
• Assessment of Environmental Cockroach Allergen Exposure

  2012cites this paper
• Characterization of Recombinant Per a 10 from Periplaneta americana

  2012cites this paper
• Serine Protease Inhibitor Attenuates Ovalbumin Induced Inflammation in Mouse Model of Allergic Airway Disease

  2012cites this paper
• Serine protease Per a 10 from Periplaneta americana bias dendritic cells towards type 2 by upregulating CD86 and low IL‐12 secretions

  2012cites this paper
• Proteolytic activity in cowshed dust extracts induces C5a release in murine bronchoalveolar lavage fluids which may account for its protective properties in allergic airway inflammation

  2012cites this paper
• Role of Allergen Source-Derived Proteases in Sensitization via Airway Epithelial Cells

  2012cites this paper
• Cockroach Induces Inflammatory Responses through Protease-Dependent Pathways

  2011cites this paper
• Mucosal exposure to cockroach extract induces allergic sensitization and allergic airway inflammation

  2011cites this paper
• Protease-activated receptor 2 activation of myeloid dendritic cells regulates allergic airway inflammation

  2011cites this paper
• Longterm persistence of proteolytic activities in frass of Blattella germanica increases its allergenic potential

  2011cites this paper
• Molecular and immunological characterization of subtilisin like serine protease, a major allergen of Curvularia lunata.

  2011cites this paper
• A new protease assay system using gelatin thin film for monitoring indoor air quality.

  2011cites this paper
• The Protease Allergen Pen c 13 Induces Allergic Airway Inflammation and Changes in Epithelial Barrier Integrity and Function in a Murine Model*

  2011cites this paper
• Fungi Linking the Pathophysiology of Chronic Rhinosinusitis with Nasal Polyps and Allergic Asthma

  2011cites this paper
• Mucosal sensitization to German cockroach involves protease-activated receptor-2

  2010cites this paper
• Enzymatic activities of allergen extracts from three species of dust mites and cockroaches commonly found in Korean home.

  2010cites this paper
• Proteolytically Inactive Per a 10 Allergen of Periplaneta americana Modulates Th2 Response and Enhances IL-10 in Mouse Model

  2010influential citation
• German Cockroach Frass Proteases Modulate the Innate Immune Response via Activation of Protease-Activated Receptor-2

  2010cites this paper
• New Insights Into Innate Immune Mechanisms Underlying Allergenicity

  2009cites this paper