Enhanced selectivity for sulfatide by engineered human glycolipid transfer protein.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Structure

• Publication date

  2011-11-09

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.str.2011.09.011PMID 22078563PMCID PMC3220887
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Directed Evolution of a Protein Container

  2011cited by this paper
• Structural Determination and Tryptophan Fluorescence of Heterokaryon Incompatibility C2 Protein (HET-C2), a Fungal Glycolipid Transfer Protein (GLTP), Provide Novel Insights into Glycolipid Specificity and Membrane Interaction by the GLTP Fold*

  2010cited by this paper
• Human GLTP: Three distinct functions for the three tryptophans in a novel peripheral amphitropic fold.

  2010cited by this paper
• Structure-guided reprogramming of serine recombinase DNA sequence specificity

  2010cited by this paper
• Multi-dimensional mass spectrometry-based shotgun lipidomics and the altered lipids at the mild cognitive impairment stage of Alzheimer's disease.

  2010cited by this paper
• Designer enzymes for glycosphingolipid synthesis by directed evolution.

  2009cited by this paper
• Basis of substrate binding and conservation of selectivity in the CLC family of channels and transporters

  2009cited by this paper
• Sulfatide, A Major Lipid Component of Myelin Sheath, Activates Inflammatory Responses As an Endogenous Stimulator in Brain-Resident Immune Cells1

  2008cited by this paper
• Endosomes and lysosomes play distinct roles in sulfatide-induced neuroblastoma apoptosis: potential mechanisms contributing to abnormal sulfatide metabolism in related neuronal diseases.

  2008cited by this paper
• The Role and Metabolism of Sulfatide in the Nervous System

  2008influential reference
• Potential mechanisms contributing to sulfatide depletion at the earliest clinically recognizable stage of Alzheimer’s disease: a tale of shotgun lipidomics

  2007cited by this paper
• Mini Review: Immune Response to Myelin-Derived Sulfatide and CNS-Demyelination

  2007cited by this paper
• CD1 mediated T cell recognition of glycolipids.

  2007cited by this paper
• Glycolipid transfer proteins.

  2007cited by this paper
• The Liganding of Glycolipid Transfer Protein Is Controlled by Glycolipid Acyl Structure

  2006cited by this paper
• Structural evidence for adaptive ligand binding of glycolipid transfer protein.

  2006cited by this paper
• Mass spectrometric analysis reveals changes in phospholipid, neutral sphingolipid and sulfatide molecular species in progressive epilepsy with mental retardation, EPMR, brain: a case study

  2005cited by this paper
• Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity

  2005cited by this paper
• Point Mutational Analysis of the Liganding Site in Human Glycolipid Transfer Protein

  2005cited by this paper
• Structural basis for glycosphingolipid transfer specificity

  2004cited by this paper
• Crystal structure of CD1a in complex with a sulfatide self antigen at a resolution of 2.15 Å

  2003cited by this paper
• Crystal structure of saposin B reveals a dimeric shell for lipid binding

  2002cited by this paper
• A fluorescence resonance energy transfer approach for monitoring protein-mediated glycolipid transfer between vesicle membranes.

  1999cited by this paper
• Fluorescence Resonance Energy Transfer Approach or Monitoring Protein-Mediated Glycolipid Transfer etween Vesicle Membranes

  1999cited by this paper
• Refinement of macromolecular structures by the maximum-likelihood method.

  1997cited by this paper
• AMoRe: an automated package for molecular replacement

  1994cited by this paper
• Automated refinement of protein models.

  1993cited by this paper
• Spontaneous lipid transfer between organized lipid assemblies.

  1992influential reference
• Synthesis and characterization of new fluorescent glycolipid probes. Molecular organisation of glycosphingolipids in mixed-composition lipid bilayers

  1991cited by this paper
• Glycolipid transfer protein and intracellular traffic of glucosylceramide

  1990cited by this paper

• Use of Bicelle-Generated Lipid Bilayer Vesicle Nanoparticles for In Vitro Measurement of Lipid Intermembrane Transport.

  2025cites this paper
• Leveraging the Thermodynamics of Protein Conformations in Drug Discovery

  2024cites this paper
• Chronic brain damage in HIV-infected individuals under antiretroviral therapy is associated with viral reservoirs, sulfatide release, and compromised cell-to-cell communication

  2023cites this paper
• The repertoire of protein-sulfatide interactions reveal distinct modes of sulfatide recognition

  2022influential citation
• Structural Predictions of the SNX-RGS Proteins Suggest They Belong to a New Class of Lipid Transfer Proteins

  2021cites this paper
• Ceramide-1-phosphate transfer protein promotes sphingolipid reorientation needed for binding during membrane interaction

  2021influential citation
• Ceramide-1-phosphate transfer protein (CPTP) regulation by phosphoinositides

  2021cites this paper
• Emerging roles for human glycolipid transfer protein superfamily members in the regulation of autophagy, inflammation, and cell death.

  2020influential citation
• Measuring Lipid Transfer Protein Activity using Bicelle-Dilution Model Membranes.

  2020cites this paper
• In Vitro Measurement of Sphingolipid Intermembrane Transport Illustrated by GLTP Superfamily Members.

  2019cites this paper
• In Silico Docking of Vitamin E Isomers on Transport Proteins.

  2019cites this paper
• Functional evaluation of tryptophans in glycolipid binding and membrane interaction by HET-C2, a fungal glycolipid transfer protein.

  2018cites this paper
• Structural analyses of 4-phosphate adaptor protein 2 yield mechanistic insights into sphingolipid recognition by the glycolipid transfer protein family

  2018influential citation
• CPTP: A sphingolipid transfer protein that regulates autophagy and inflammasome activation†

  2018cites this paper
• Sphingolipids and their metabolism in physiology and disease

  2017cites this paper
• How α-Helical Motifs Form Functionally Diverse Lipid-Binding Compartments.

  2017cites this paper
• Phosphatidylserine Stimulates Ceramide 1-Phosphate (C1P) Intermembrane Transfer by C1P Transfer Proteins*

  2016cites this paper
• Specificity of the mammalian glycolipid transfer proteins.

  2016cites this paper
• Sphingolipid transfer proteins defined by the GLTP-fold

  2015influential citation
• Studies on interactions of norovirus capsid protein with fucosylated glycans and galactosylceramide as soluble and membrane bound ligands

  2014cites this paper
• Membranes and mammalian glycolipid transferring proteins.

  2014cites this paper
• Arabidopsis accelerated cell death 11, ACD11, is a ceramide-1-phosphate transfer protein and intermediary regulator of phytoceramide levels.

  2014influential citation
• Nonvesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids

  2013cites this paper
• Chemical Tools for Studying the Biological Function of Glycolipids

  2013cites this paper
• The glycolipid transfer protein (GLTP) domain of phosphoinositol 4-phosphate adaptor protein-2 (FAPP2): structure drives preference for simple neutral glycosphingolipids.

  2013cites this paper
• GLTP-fold interaction with planar phosphatidylcholine surfaces is synergistically stimulated by phosphatidic acid and phosphatidylethanolamine[S]

  2013cites this paper
• The enigmatic role of sulfatides: new insights into cellular functions and mechanisms of protein recognition.

  2013cites this paper