Production by lithocholic acid of DNA strand breaks in L1210 cells.

No abstract is available for this paper.

• Publication year

  1980

• Venue

  Cancer Research

• Publication date

  1980-08-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  PMID 7388816
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effect of cholesterol metabolites and promoting effect of lithocholic acid in colon carcinogenesis in germ-free and conventional F344 rats.

  1979cited by this paper
• Transformation of hamster embryo cells by cholesterol-α-epoxide and lithocholic acid*

  1979cited by this paper
• Transformation of hamster embryo cells by cholesterol-alpha-epoxide and lithocholic acid.

  1979cited by this paper
• Stimulation of thymidine incorporation in mouse liver and biliary tract epithelium by lithocholate and deoxycholate.

  1978cited by this paper
• Does bile promote extra-colonic cancer?

  1978cited by this paper
• Bile acids: co-mutagenic activity in the Salmonella-mammalian-microsome mutagenicity test: brief communication.

  1977cited by this paper
• Fecal bile acids and neutral sterols in patients with familial polyposis

  1976cited by this paper
• Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.

  1976cited by this paper
• Detection and repair of single-strand breaks in nuclear DNA

  1976cited by this paper
• Enhancement of postreplication repair in Chinese hamster cells.

  1976cited by this paper
• In vitro DNA damage/alkaline elution assay for predicting carcinogenic potential.

  1976cited by this paper
• Fractionation of DNA from mammalian cells by alkaline elution.

  1976cited by this paper
• Supercoils in human DNA.

  1975cited by this paper
• Faecal bile-acids and clostridia in patients with cancer of the large bowel.

  1975cited by this paper
• Promoting effect of bile acids on colon carcinogenesis after intrarectal instillation of N-methyl-N'-nitro-N-nitrosoguanidine in rats.

  1974cited by this paper
• Effects of dietary fat level and dimethylhydrazine on fecal acid and neutral sterol excretion and colon carcinogenesis in rats.

  1974cited by this paper
• Phenomenology of an inducible mutagenic DNA repair pathway in Escherichia coli: SOS repair hypothesis

  1974cited by this paper
• Effect of lithocholic acid on DL-ethionine carcinogenesis in rat liver.

  1971cited by this paper

• Systematic identification of secondary bile acid production genes in global microbiome

  2024cites this paper
• Swertiamarin relieves radiation-induced intestinal injury by limiting DNA damage

  2024cites this paper
• A Narrative Review: Immunometabolic Interactions of Host–Gut Microbiota and Botanical Active Ingredients in Gastrointestinal Cancers

  2024cites this paper
• Bile Acids, Gut Microbes, and the Neighborhood Food Environment—a Potential Driver of Colorectal Cancer Health Disparities

  2022cites this paper
• Gut Microbiome-Linked Metabolites in the Pathobiology of Major Depression With or Without Anxiety—A Role for Bile Acids

  2022cites this paper
• Destination and Specific Impact of Different Bile Acids in the Intestinal Pathogen Clostridioides difficile

  2022cites this paper
• Dietary fat, bile acid metabolism and colorectal cancer.

  2020cites this paper
• Obesity and cancer: A mechanistic overview of metabolic changes in obesity that impact genetic instability

  2019cites this paper
• Regulation of bile acids by prebiotic food components: Studies in rat caecum and in serum of mice and humans

  2018cites this paper
• Influence of Bile Acids on Colorectal Cancer Risk: Potential Mechanisms Mediated by Diet-Gut Microbiota Interactions

  2017cites this paper
• Consequences of bile salt biotransformations by intestinal bacteria

  2016cites this paper
• The human gut sterolbiome: bile acid-microbiome endocrine aspects and therapeutics

  2015cites this paper
• Effect of Soyasaponin Fractions on Human Colon Cancer Cells

  2011cites this paper
• Bile acids as possible human carcinogens: new tricks from an old dog

  2009cites this paper
• Effects of Lactobacillus acidophilus 43121 and a Mixture of Lactobacillus casei and Bifidobacterium longum on the Serum Cholesterol Level and Fecal Sterol Excretion in Hypercholesterolemia-Induced Pigs

  2008cites this paper
• Requirements for Induction of DMA Strand Breaks by Lithocholic Acid 1

  2006cites this paper
• Bile acids as carcinogens in human gastrointestinal cancers.

  2005cites this paper
• Effect of hyperthermia and doxorubicin on nucleoid sedimentation and poly (ADP-ribose) Polymerase activity in L1210 cells

  2004cites this paper
• Effects of bile acids on the mutagenicity and recombinogenicity of triethylene melamine in yeast strains MP1 and D61.M

  2004cites this paper
• The role of bile acids in carcinogenesis.

  2001cites this paper
• The induction of SOS function in Escherichia coli K-12/PQ37 by 4-nitroquinoline oxide (4-NQO) and fecapentaenes-12 and -14 is bile salt sensitive: implications for colon carcinogenesis.

  2000cites this paper
• Lithocholic Acid, a Putative Tumor Promoter, Inhibits Mammalian DNA Polymerase β

  1998cites this paper
• Primary biliary cirrhosis in patients with breast cancer: studying the link.

  1998cites this paper
• The stress-response proteins poly(ADP-ribose) polymerase and NF-κB protect against bile salt-induced apoptosis

  1998cites this paper
• Factors influencing the development of sigmoid colon cancer: Bacteriologic and biochemical studies

  1996cites this paper
• Role of bile acids in colorectal carcinogenesis.

  1995cites this paper
• Effect of dietary fiber on serum bile acids in patients with chronic cholestatic liver disease under ursodeoxycholic acid therapy.

  1995cites this paper
• Bile acids do not form adducts when incubated with DNA in vitro.

  1994cites this paper
• Influence of dietary cholesterol on facal steroid excretion and its impact on the colonic epithelium in mice: Implications for colon carcinogenesis

  1993cites this paper
• Lithocholic acid-sensitive mutant cells isolated from Chinese hamster ovary cells are cross-sensitive to cytoskeleton-disturbing agents.

  1993cites this paper
• Lithocholic acid-sensitive mutant cells isolated from Chinese hamster ovary cells are cross-sensitive to cytoskeleton-disturbing agents.

  1993cites this paper
• Bile acids influence the growth, oestrogen receptor and oestrogen-regulated proteins of MCF-7 human breast cancer cells.

  1992cites this paper
• Neoplasms and nonneoplastic liver lesions in winter flounder, Pseudopleuronectes americanus, from Boston Harbor, Massachusetts.

  1991cites this paper
• Involvement of fos in spontaneous and ultraviolet light‐induced genetic changes

  1991cites this paper
• Promotion of hepatocellular foci in female rats by chenodeoxycholic acid.

  1991cites this paper
• Biliary bile acid profiles in familial adenomatous polyposis

  1991cites this paper
• Enhanced preneoplastic liver lesion development under 'selection pressure' conditions after administration of deoxycholic or lithocholic acid in the initiation phase in rats.

  1990cites this paper
• Multiple copies of a bile acid-inducible gene in Eubacterium sp. strain VPI 12708

  1990cites this paper
• Chromosomal aberrations as a contributing factor for tumor promotion in the mouse skin.

  1989cites this paper
• Evidence for a multigene family involved in bile acid 7-dehydroxylation in Eubacterium sp. strain VPI 12708

  1988cites this paper
• Effect of adriamycin and hyperthermia on the sedimentation of nucleoids from L1210 cells.

  1988cites this paper
• The development of hepatobiliary cancer in a carrier of Salmonella typhus.

  1988cites this paper
• Cocarcinogenic activity of bile acids in the chemical transformation of C3H/10T1/2 fibroblasts in vitro.

  1988cites this paper
• Nucleotide sequence and regulation of a gene involved in bile acid 7-dehydroxylation by Eubacterium sp. strain VPI 12708

  1988cites this paper
• Bile Acids and Colonic Carcinogenesis

  1988cites this paper
• Effect of adriamycin and hyperthermia on the sedimentation of nucleoids from L1210 cells.

  1988cites this paper
• Role of bile acids and neutral sterols in carcinogenesis.

  1988cites this paper
• Molecular cloning of a gene encoding a 45,000-dalton polypeptide associated with bile acid 7-dehydroxylation in Eubacterium sp. strain VPI 12708

  1988cites this paper
• Molecular cloning of bile acid 7-dehydroxylase from Eubacterium sp. strain VPI 12708

  1987cites this paper
• Induction of gamma-glutamyltranspeptidase-positive foci in rat liver by deoxycholic acid.

  1987cites this paper
• Chronic ursodeoxycholic acid- and chenodeoxycholic acid-feeding-induced changes of colon mucosal cell proliferation in rats.

  1987cites this paper
• Characterization of the effects induced on DNA in mouse and hamster cells by lithocholic acid.

  1987cites this paper
• Restoration of hyperthermia-associated increased protein to DNA ratio of nucleoids.

  1987cites this paper
• DNA damage and repair in epithelial (mucous) cells and crypt cells from isolated colon.

  1985cites this paper
• Diet, nutrition intake, and metabolism in populations at high and low risk for colon cancer. Introduction: correlates of diet, nutrient intake, and metabolism in relation to colon cancer.

  1984cites this paper
• Mitotic aneuploidy as a possible mechanism for tumour promoting activity in bile acids.

  1984cites this paper
• Report of ICPEMC Task Group 5 on the differentiation between genotoxic and non-genotoxic carcinogens.

  1984cites this paper
• Bacterial Mutagenesis and Cell Transformation Assays of Pyrvinium Pamoate (Povan), An Antiparasitic Agent

  1984cites this paper
• Role of bile acids and neutral sterols in familial cancer syndromes of the colon

  1983cites this paper
• Effect of dietary cholesterol on azoxymethane-induced colon carcinogenesis in rats.

  1983cites this paper
• Modification of the carcinogenic process in colorectal cancer by endogenous and exogenous factors: effect of colestipol hydrochloride on tumors induced by dimethylhydrazine.

  1983cites this paper
• Carcinogenesis and aging. II. Modifying effect of aging on metabolism of methyl(acetoxymethyl)nitrosamine and its interaction with DNA of various tissues in rats.

  1983cites this paper
• Tissue bile acids in patients with colon cancer and colonic polyps.

  1982cites this paper
• Clastogenic activity of bile acids and organic acid fractions of human feces.

  1982cites this paper
• Bile salts and the liver.

  1982cites this paper
• Requirements for induction of DNA strand breaks by lithocholic acid.

  1982cites this paper
• Ursodeoxycholic acid in the treatment of cholesterol cholelithiasis part II

  1982cites this paper
• The physiological importance of the colonic microflora.

  1982cites this paper
• Cofactor requiremets for 7 alpha-dehydroxylation of cholic and chenodeoxycholic acid in cell extracts of the intestinal anaerobic bacterium, Eubacterium species V.P.I. 13708.

  1981cites this paper