Analysis of the respiratory effects of cannabinoids in rats

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Naunyn-Schmiedeberg's Archives of Pharmacology

• Publication date

  2003-09-10

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/s00210-003-0787-3PMID 13680088
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cardiovascular effects.

  2005cited by this paper
• The peripheral sympathetic nervous system is the major target of cannabinoids in eliciting cardiovascular depression

  2003cited by this paper
• Effects of imidazoline antihypertensive drugs on sympathetic tone and noradrenaline release in the prefrontal cortex

  2001cited by this paper
• Effects of cannabinoids on sympathetic and parasympathetic neuroeffector transmission in the rabbit heart.

  2001cited by this paper
• Modulation of the cardiac autonomic transmission of pithed rats by presynaptic opioid OP4 and cannabinoid CB1 receptors

  2001cited by this paper
• Effects of cannabinoids on adrenaline release from adrenal medullary cells

  2001cited by this paper
• Cardiovascular effects of endocannabinoids--the plot thickens.

  2000cited by this paper
• Cannabinoids cause central sympathoexcitation and bradycardia in rabbits.

  2000cited by this paper
• Bidirectional control of airway responsiveness by endogenous cannabinoids

  2000cited by this paper
• Pharmacology of cannabinoid receptor ligands.

  1999cited by this paper
• Effect of the cannabinoid receptor agonist WIN55212‐2 on sympathetic cardiovascular regulation

  1999cited by this paper
• Central control of the cardiovascular and respiratory systems and their interactions in vertebrates.

  1999cited by this paper
• Analgesic, respiratory and heart rate effects of cannabinoid and opioid agonists in rhesus monkeys: antagonist effects of SR 141716A.

  1998cited by this paper
• Cardiovascular actions of cannabinoids and their generation during shock

  1998cited by this paper
• Analgesic , Respiratory and Heart Rate Effects of Cannabinoid and Opioid Agonists in Rhesus Monkeys : Antagonist Effects of SR 141716 A 1 , 2

  1998cited by this paper
• Cannabinoid CB1 receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat

  1997cited by this paper
• Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats.

  1997cited by this paper
• Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.

  1997influential reference
• Cardiovascular effects of (-)-11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl in rats.

  1996cited by this paper
• Mechanism of the hypotensive action of anandamide in anesthetized rats.

  1996influential reference
• Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.

  1996cited by this paper
• Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB 1 receptors on peripheral sympathetic nerves

  1996cited by this paper
• Cardiovascular effects of (−)-11-OH-Δ8-tetrahydrocannabinol-dimethylheptyl in rats

  1996cited by this paper
• A Systems View of Respiratory Regulation

  1996cited by this paper
• Novel antagonist implicates the CB1 cannabinoid receptor in the hypotensive action of anandamide.

  1995cited by this paper
• Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.

  1995cited by this paper
• Regional Cerebral Blood Flow after Marijuana Smoking

  1992cited by this paper
• Characterization of the absorption phase of marijuana smoking

  1992cited by this paper
• Effects of hypercapnia and hypoxia on the cardiovascular system: vascular capacitance and aortic chemoreceptors.

  1990cited by this paper
• Cardiovascular effects of Δ9- andΔ9(11)-tetrahydrocannabinol and their interaction with epinephrine

  1987influential reference
• Cardiovascular effects of delta 9- and delta 9(11)-tetrahydrocannabinol and their interaction with epinephrine.

  1987cited by this paper
• Effects of diethyl ether, halothane, ketamine and urethane on sympathetic activity in the rat.

  1987cited by this paper
• Cannabinoid pharmacology.

  1986cited by this paper
• Cellular effects of cannabinoids.

  1986cited by this paper
• Synaptic mechanisms involved in the inspiratory modulation of vagal cardio‐inhibitory neurones in the cat.

  1984cited by this paper
• Respiratory and cardiovascular depressant effects of nabilone, N-methyllevonantradol and delta 9-tetrahydrocannabinol in anesthetized cats.

  1983cited by this paper
• Delta9-tetrahydrocannabinol: depression of ventilatory regulation; other respiratory and cardiovascular effects.

  1976cited by this paper
• Respiratory modulation of barareceptor and chemoreceptor reflexes affecting heart rate and cardiac vagal efferent nerve activity.

  1976cited by this paper
• Δ9-Tetrahydrocannabinol: Depression of ventilatory regulation; Other respiratory and cardiovascular effects

  1976influential reference
• Intravenous Δ9‐Tetrahydrocannabinol: Effects on Ventilatory Control and Cardiovascular Dynamics

  1975influential reference
• Combination of Δ9‐Tetrahydrocannabinol with Oxymorphone or Pentobarbital: Effects on Ventilatory Control and Cardiovascular Dynamics

  1975cited by this paper
• Baroreceptor and chemoreceptor influences on heart rate during the respiratory cycle in the dog.

  1975influential reference
• Intravenous delta9-Tetrahydrocannabinol: Effects of ventilatory control and cardiovascular dynamics.

  1975cited by this paper
• Inhalation, parenteral and oral LD50 values of delta 9-tetrahydrocannabinol in Fischer rats.

  1974cited by this paper
• Inhalation, parenteral and oral LD50 values of Δ9-tetrahydrocannabinol in Fischer rats

  1974influential reference
• Cardiovascular and respiratory effects of cannabis in cat and rat

  1973cited by this paper
• Certain observations on interrelationships between respiratory and cardiovascular effects of (-)- 9 -trans-tetrahydrocannabinol.

  1972cited by this paper
• Acute toxicity of delta-9-tetrahydrocannabinol in rats and mice.

  1971cited by this paper
• Acute Toxicity of Δ9-Tetrahydrocannabinol in Rats and Mice 1

  1971cited by this paper
• The effects of artificially induced hyperventilation on the primary cardiac reflex response to stimulation of the carotid bodies in the dog

  1963cited by this paper

• CB1 cannabinoid receptor agonists induce acute respiratory depression in awake mice

  2025cites this paper
• Synthetic cannabinoid receptor agonists exacerbate fentanyl-elicited respiratory depression and confer resistance to naloxone rescue in mice.

  2025cites this paper
• Exploring the Impact of Chirality of Synthetic Cannabinoids and Cathinones: A Systematic Review on Enantioresolution Methods and Enantioselectivity Studies

  2025cites this paper
• Evidence for enduring cardiac and multiorgan toxicity after repeated exposure to the synthetic cannabinoid JWH-018 in male rats.

  2024cites this paper
• Sex‐ and age‐specific respiratory alterations induced by prenatal exposure to the cannabinoid receptor agonist WIN 55,212‐2 in rats

  2023cites this paper
• Inhaled Δ9-tetrahydrocannabinol does not enhance oxycodone-induced respiratory depression: randomised controlled trial in healthy volunteers.

  2023cites this paper
• Δ^9-Tetrahydrocannabinol Effects on Respiration and Heart Rate Across Route of Administration in Female and Male Mice

  2023cites this paper
• Acute Cardiovascular and Cardiorespiratory Effects of JWH-018 in Awake and Freely Moving Mice: Mechanism of Action and Possible Antidotal Interventions?

  2023cites this paper
• The endocannabinoid system and breathing

  2023influential citation
• The Old and the New: Cardiovascular and Respiratory Alterations Induced by Acute JWH-018 Administration Compared to Δ9-THC—A Preclinical Study in Mice

  2023influential citation
• In Vivo Bio-Activation of JWH-175 to JWH-018: Pharmacodynamic and Pharmacokinetic Studies in Mice

  2022cites this paper
• Synthetic cannabinoids in Europe – a review

  2021influential citation
• Brain Penetrant, but not Peripherally Restricted, Synthetic Cannabinoid 1 Receptor Agonists Promote Morphine-Mediated Respiratory Depression

  2021cites this paper
• Respiratory failure in confirmed synthetic cannabinoid overdose

  2021cites this paper
• Pharmacological and Toxicological Effects of Phytocannabinoids and Recreational Synthetic Cannabinoids: Increasing Risk of Public Health

  2021cites this paper
• Functional role for preoptic CB1 receptors in breathing and thermal control.

  2020cites this paper
• Cannabinoid CB2 Receptor Activation Attenuates Fentanyl-Induced Respiratory Depression

  2020cites this paper
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  2019cites this paper
• Ventilatory‐depressant effects of opioids alone and in combination with cannabinoids in rhesus monkeys

  2018cites this paper
• Betacaryophyllene - A phytocannabinoid as potential therapeutic modality for human sepsis?

  2018cites this paper
• CB1 receptor-mediated respiratory depression by endocannabinoids.

  2017cites this paper
• Fatty acid amide hydrolase-morphine interaction influences ventilatory response to hypercapnia and postoperative opioid outcomes in children.

  2017cites this paper
• Synthetic cannabinoid induced acute respiratory depression: Case series and literature review

  2017cites this paper
• A new side effect of synthetic cannabinoid use by the bucket (waterpipe) method: Acute respiratory distress syndrome (ARDS)

  2017cites this paper
• Recreational drug use and the emerging challenges of psychoactive substances in Malta : a case series

  2017cites this paper
• Endocannabinoids in cerebrovascular regulation.

  2016cites this paper
• The Effects of Synthetic Cannabinoids on Alveolar-Arterial Oxygen Gradient

  2016cites this paper
• The Wide and Unpredictable Scope of Synthetic Cannabinoids Toxicity

  2015cites this paper
• In utero cannabinoid exposure alters breathing and the response to hypoxia in newborn mice

  2014influential citation
• Role of Endocannabinoids and Cannabinoid-1 Receptors in Cerebrocortical Blood Flow Regulation

  2013influential citation
• Synthetische Cannabinoide

  2012cites this paper
• Contribution à l'étude de la morbi-mortalité lors de l'usage de drogues récréatives : GHB-THC, seuls ou associés à l'éthanol

  2012cites this paper
• DOCTORAT DE L'UNIVERSITE PARIS DESCARTES

  2012cites this paper
• Synthetic Cannabis and Respiratory Depression

  2012cites this paper
• Inactivation of Anandamide Signaling: A Continuing Debate

  2010cites this paper
• Midcervical vagotomy precludes respiratory response to novel anti-inflammatory and anti-tumour drug arvanil in rats.

  2010cites this paper
• Anandamide centrally depresses the respiratory rhythm generator of neonatal mice.

  2010cites this paper
• DOSE-DEPENDENT EFFECTS ON VENTILATION AT REST INDUCED BY HIGH DOSES OF CANNABINOIDS IN RATS

  2010influential citation
• Role of VR1 and CB1 receptors in modelling of cardio-respiratory response to arvanil, an endocannabinoid and vanilloid hybrid, in rats.

  2008cites this paper
• The contribution of VR1 and CB1 receptors and the role of the afferent vagal pathway in modelling of cardio-respiratory effects of anandamide in rats.

  2007cites this paper
• Supranodose vagotomy eliminates anandamide-evoked cardiorespiratory depression in anaesthetized rats.

  2006cites this paper
• The Endocannabinoid System as an Emerging Target of Pharmacotherapy

  2006cites this paper
• Search for an endogenous cannabinoid-mediated effect in the sympathetic nervous system

  2005cites this paper
• Cannabinoid suppressed bicuculline-induced convulsion without respiratory depression in the brainstem-spinal cord preparation from newborn rats.

  2005cites this paper
• The endocannabinoid signalling system: Implications for anaesthesia and the pain clinic

  2005cites this paper
• Cannabinoid receptor expression in peripheral arterial chemoreceptors during postnatal development.

  2004cites this paper
• The endocannabinoid system and its therapeutic exploitation

  2004cites this paper
• Gastric antisecretory effects of synthetic cannabinoids after central or peripheral administration in the rat.

  2004cites this paper
• Central effects of the cannabinoid receptor agonist WIN55212‐2 on respiratory and cardiovascular regulation in anaesthetised rats

  2004cites this paper