Effects of Different Adjuvants in the Context of Intramuscular and Intranasal Routes on Humoral and Cellular Immune Responses Induced by Detergent-Split A/H3N2 Influenza Vaccines in Mice

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Clinical and Vaccine Immunology

• Publication date

  2011-12-21

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/CVI.05441-11PMID 22190392PMCID PMC3272927
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Immunogenicity and safety in adults of one dose of influenza A H1N1v 2009 vaccine formulated with and without AS03A-adjuvant: preliminary report of an observer-blind, randomised trial.

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• Characterisation of myeloid receptor expression and interferon alpha/beta production in murine plasmacytoid dendritic cells by flow cytomtery.

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  2009cited by this paper
• Emergence of a novel swine-origin influenza A (H1N1) virus in humans.

  2009cited by this paper
• Cutting Edge: Inflammasome Activation by Alum and Alum’s Adjuvant Effect Are Mediated by NLRP31

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• Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

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• Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

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• Vaccines Against Pandemic Influenza: What Can be Done Before the Next Pandemic?

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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
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  2007cited by this paper
• The humoral immune response and protective efficacy of vaccination with inactivated split and whole influenza virus vaccines in BALB/c mice.

  2006cited by this paper
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  2006cited by this paper
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  2006cited by this paper
• Influenza and the challenge for immunology

  2006cited by this paper
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  2006cited by this paper
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  2005cited by this paper
• A novel intranasal Protollin-based measles vaccine induces mucosal and systemic neutralizing antibody responses and cell-mediated immunity in mice.

  2005cited by this paper
• Aluminium adjuvants--in retrospect and prospect.

  2004cited by this paper
• Aluminium compounds for use in vaccines

  2004cited by this paper
• Protollin: a novel adjuvant for intranasal vaccines.

  2004cited by this paper
• A nasal Proteosome influenza vaccine containing baculovirus-derived hemagglutinin induces protective mucosal and systemic immunity.

  2003cited by this paper
• Surveillance for influenza--United States, 1997-98, 1998-99, and 1999-00 seasons.

  2002cited by this paper
• WHO Manual on Animal Influenza Diagnosis and Surveillance

  2002cited by this paper
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  2001cited by this paper
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• Tlr4: central component of the sole mammalian LPS sensor.

  2000influential reference
• Aluminium‐induced granulomas after inaccurate intradermal hyposensitization injections of aluminium‐adsorbed depot preparations

  2000cited by this paper
• Effectiveness and cost-benefit of influenza vaccination of healthy working adults: A randomized controlled trial.

  2000cited by this paper
• Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2.

  1999cited by this paper
• Adjuvants--a classification and review of their modes of action.

  1997cited by this paper
• Intransal or intragastric immunization with proteosome-Shigella lipopolysaccharide vaccines protects against lethal pneumonia in a murine model of Shigella infection

  1995cited by this paper
• Adjuvants--a balance between toxicity and adjuvanticity.

  1993cited by this paper
• Immunogenicity and efficacy of oral or intranasal Shigella flexneri 2a and Shigella sonnei proteosome-lipopolysaccharide vaccines in animal models

  1993cited by this paper
• Modulation of the human immune response by the non-toxic and non-pyrogenic adjuvant aluminium hydroxide: effect on antigen uptake and antigen presentation.

  1985cited by this paper
• Immunity to influenza in man.

  1983cited by this paper
• Side effects during immunotherapy with purified grass pollen extracts.

  1982cited by this paper
• Side Effects during Immunotherapy with Purified Grass Pollen Extracts

  1982cited by this paper
• Genetic relatedness between the new 1977 epidemic strains (H1N1) of influenza and human influenza strains isolated between 1947 and 1957 (H1N1).

  1978cited by this paper
• Brain Aluminum Distribution in Alzheimer's Disease and Experimental Neurofibrillary Degeneration

  1973cited by this paper

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• Advances in Adjuvanted Influenza Vaccines

  2023cites this paper
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  2023cites this paper
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  2022cites this paper
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  2021cites this paper
• Development of spike receptor-binding domain nanoparticle as a vaccine candidate against SARS-CoV-2 infection in ferrets

  2021influential citation
• Protective antibodies elicited by SARS-CoV-2 spike protein vaccination are boosted in the lung after challenge in nonhuman primates

  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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• Early suppression of B cell immune responses by low doses of chloroquine and pyrimethamine: implications for studying immunity in malaria

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• Protamine Nanocapsules for the Development of Thermostable Adjuvanted Nanovaccines.

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