Osteochondral regeneration using a novel aragonite-hyaluronate bi-phasic scaffold in a goat model

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Knee Surgery, Sports Traumatology, Arthroscopy

• Publication date

  2014-06-01

• Fields of study

  Medicine, Engineering

• Identifiers
  DOI 10.1007/s00167-013-2467-2PMID 23479056
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Electrospinning of polymeric nanofibers for drug delivery applications.

  2014cited by this paper
• Scaffold-based repair for cartilage healing: a systematic review and technical note.

  2013cited by this paper
• Influence of in vitro maturation of engineered cartilage on the outcome of osteochondral repair in a goat model.

  2012cited by this paper
• ACI and MACI

  2012cited by this paper
• A novel nano-structured porous polycaprolactone scaffold improves hyaline cartilage repair in a rabbit model compared to a collagen type I/III scaffold: in vitro and in vivo studies

  2012cited by this paper
• What is a systematic review?

  2011cited by this paper
• Novel Nano-composite Multilayered Biomaterial for Osteochondral Regeneration

  2011cited by this paper
• The regenerative effect of platelet-rich plasma on healing in large osteochondral defects

  2010cited by this paper
• Platelet autologous growth factors decrease the osteochondral regeneration capability of a collagen-hydroxyapatite scaffold in a sheep model

  2010cited by this paper
• A Hyaluronate–Atelocollagen/β-Tricalcium Phosphate–Hydroxyapatite Biphasic Scaffold for the Repair of Osteochondral Defects: A Porcine Study

  2010cited by this paper
• A New Histology Scoring System for the Assessment of the Quality of Human Cartilage Repair: ICRS II

  2010cited by this paper
• Mid-term results of Autologous Matrix-Induced Chondrogenesis for treatment of focal cartilage defects in the knee

  2010cited by this paper
• Delayed incorporation of a TruFit plug: perseverance is recommended.

  2009cited by this paper
• Matrix-Assisted Autologous Chondrocyte Transplantation for the Repair of Cartilage Defects of the Knee

  2009cited by this paper
• Preclinical animal models in single site cartilage defect testing: a systematic review.

  2008cited by this paper
• Second Generation Issues in Cartilage Repair

  2008cited by this paper
• Electrospinning of Polymeric Nanofibers for Tissue Engineering Applications: A Review

  2006cited by this paper
• Alginate‐Based Nanofibrous Scaffolds: Structural, Mechanical, and Biological Properties

  2006cited by this paper
• Phospholipid Nonwoven Electrospun Membranes

  2006cited by this paper
• Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision.

  2006cited by this paper
• Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering

  2005cited by this paper
• Electrospun chitosan-based nanofibers and their cellular compatibility.

  2005cited by this paper
• Inhibition of interleukin-1beta-stimulated production of matrix metalloproteinases by hyaluronan via CD44 in human articular cartilage.

  2004cited by this paper
• Inhibition of interleukin-1β-stimulated production of matrix metalloproteinases by hyaluronan via CD44 in human articular cartilage

  2004cited by this paper
• The effect of hyaluronan on CD44-mediated survival of normal and hydroxyl radical-damaged chondrocytes.

  2003cited by this paper
• Natural coral exoskeleton as a bone graft substitute: A review

  2002influential reference
• Hard tissue remodeling using biofabricated coralline biomaterials.

  2002cited by this paper
• Applications

  2001cited by this paper
• Anti-Fas-induced apoptosis in chondrocytes reduced by hyaluronan: evidence for CD44 and CD54 (intercellular adhesion molecule 1) invovement.

  2001cited by this paper
• Hyaluronan and hyaluronan-binding proteins. Probes for specific detection.

  2001cited by this paper
• Hyaluronan‐based polymers in the treatment of osteochondral defects

  2000cited by this paper
• Nos ancêtres les coraux.

  2000cited by this paper
• Tissue engineering of biphasic joint cartilage transplants.

  1999influential reference
• Coralline bone graft substitutes.

  1999cited by this paper
• Coral graft restoration of osteochondral defects.

  1998cited by this paper
• Evaluation of proliferation and protein expression of human bone marrow cells cultured on coral crystallized in the aragonite of calcite form.

  1998cited by this paper
• Hyaluronic acid inhibits interleukin-1-induced superoxide anion in bovine chondrocytes

  1997cited by this paper
• [Additive medial osteotomy of the tibia locked with a coral callus. First results apropos of 38 operations].

  1997cited by this paper
• Adhesion, growth and differentiation of human bone marrow stromal cells on non-porous calcium carbonate and plastic substrata: effects of dexamethasone and 1,25dihydroxyvitamin D3

  1996cited by this paper
• Bone marrow induced osteogenesis in hydroxyapatite and calcium carbonate implants.

  1996cited by this paper
• Natural coral as a substrate for fibroblastic growth in vitro

  1993influential reference
• [Coral substituted for bone grafting in posterior vertebral arthrodesis in children. Initial results].

  1989cited by this paper
• Ossification de corail implanté dans une mâchoire d'ovin: détermination quantitative par des méthodes physiques et étude anatomo-pathologique

  1989cited by this paper
• Comparison of coral resorption and bone apposition with two natural corals of different porosities.

  1989cited by this paper
• Madreporic coral: a new bone graft substitute for cranial surgery.

  1988cited by this paper
• [Madreporal periapical augmentation. Clinical experience in use of a madrepore filling material for loss of periapical bone].

  1988cited by this paper
• [Madreporic coral].

  1987cited by this paper
• The use of coral as a bone graft substitute.

  1987cited by this paper
• Substrate-bonded hyaluronic acid exhibits a size-dependent stimulation of chondrogenic differentiation of stage 24 limb mesenchymal cells in culture.

  1986cited by this paper
• The chondrogenic potential of free autogenous periosteal grafts for biological resurfacing of major full-thickness defects in joint surfaces under the influence of continuous passive motion. An experimental investigation in the rabbit.

  1986cited by this paper
• Coral, a new biomedical material. Experimental and first clinical investigations on Madreporaria.

  1985cited by this paper
• Particle size of periodontal bone grafting materials.

  1984cited by this paper
• [Use of Madreporaria coral skeletons in reparative surgery].

  1983cited by this paper
• [Fate of a fragment of madrepore coral skeleton implanted in the diaphysis of long bones in dogs].

  1981cited by this paper
• [Use of madreporaria coral skeletal fragments in orthopedic and reconstructive surgery: experimental studies and human clinical application (author's transl)].

  1980cited by this paper
• Tissue ingrowth of Replamineform implants.

  1975cited by this paper

• Subchondral bone repair potential of an osteochondral scaffold augmented with BMP-2 or strontium-enriched amorphous calcium phosphate: a co-culture in vitro model.

  2026cites this paper
• Clinical Experience With an Aragonite-Based Scaffold Implant for Knee Cartilage Repair: A Multicenter Case Series

  2025cites this paper
• Osteochondral solutions for cartilage lesions of the knee: a narrative review

  2025cites this paper
• Female patients report comparable results to males after the implantation of an aragonite-based scaffold for the treatment of knee chondral and osteochondral defects: a gender-based analysis of a RCT at 4 years’ follow-up

  2025cites this paper
• Matrices Used for Cartilage Regeneration.

  2025cites this paper
• Report on Evolving Indications, Techniques, and Outcome of Novel and Innovative Surgical procedure – Agili C®

  2025influential citation
• Osteochondral Knee Joint Lesion Treated With an Aragonite-Based Scaffold. 12-Year Follow-Up of the World's First Implantation: Case Report.

  2025cites this paper
• Acellular Aragonite-Based Scaffold for the Treatment of Joint Surface Lesions of the Knee: A Minimum 5-Year Follow-Up Study

  2024cites this paper
• Multilayered Cryogel Enriched with Exosomes Regenerates and Maintains Cartilage Architecture and Phenotype in Goat Osteochondral Injuries.

  2024cites this paper
• Differential analysis of the impact of lesions’ location on clinical and radiological outcomes after the implantation of a novel aragonite-based scaffold to treat knee cartilage defects

  2024cites this paper
• Die Bedeutung des subchondralen Knochens in der Behandlung von Knorpeldefekten

  2024cites this paper
• Aragonite-Based Scaffold Versus Microfracture and Debridement for the Treatment of Knee Chondral and Osteochondral Lesions: Results of a Multicenter Randomized Controlled Trial

  2023cites this paper
• Nanosilicate‐Reinforced Silk Fibroin Hydrogel for Endogenous Regeneration of Both Cartilage and Subchondral Bone

  2022cites this paper
• Articular cartilage and osteochondral tissue engineering techniques: Recent advances and challenges

  2021cites this paper
• Recuperation and characterization of calcium carbonate from residual oyster and clamshells and their incorporation into a residential finish.

  2021cites this paper
• Hyaluronic-Acid-Based Organic-Inorganic Composites for Biomedical Applications

  2021cites this paper
• Scaffolds for Cartilage Repair

  2021cites this paper
• Coral-Based Bioscaffold for the Treatment of Osteochondral Lesions of the Knee

  2021cites this paper
• Joint Surface Lesions in the Knee Treated with an Acellular Aragonite-Based Scaffold: A 3-Year Follow-Up Case Series

  2021cites this paper
• Small Ruminant Models for Articular Cartilage Regeneration by Scaffold-Based Tissue Engineering

  2021cites this paper
• Aragonite-Based Scaffold for the Treatment of Joint Surface Lesions in Mild to Moderate Osteoarthritic Knees: Results of a 2-Year Multicenter Prospective Study

  2021cites this paper
• Complex Osteochondral Lesions of the Talus Treated With a Novel Bi-Phasic Aragonite-based Implant.

  2020cites this paper
• Osteochondral Injury, Management and Tissue Engineering Approaches

  2020cites this paper
• Management of Large Focal Chondral and Osteochondral Defects in the Knee

  2020cites this paper
• Aragonite-based Scaffold for the Treatment of Joint Surface

  2020cites this paper
• Reconstruction of Large Osteochondral Defects Using a Hemicondylar Aragonite-based Implant in a Caprine Model.

  2020cites this paper
• Characterisation of Polymesoda bengalensis Shell Powder

  2020cites this paper
• Recent advances and future trends in articular cartilage repair

  2020cites this paper
• Single/two-step scaffold-based cartilage repair in the knee and ankle joint

  2019cites this paper
• Advances of nanotechnology in osteochondral regeneration.

  2019cites this paper
• MaioRegen Osteochondral Substitute for the Treatment of Knee Defects: A Systematic Review of the Literature

  2019influential citation
• Current Trends in the Evaluation of Osteochondral Lesion Treatments: Histology, Histomorphometry, and Biomechanics in Preclinical Models

  2019cites this paper
• Therapeutic Potential of Articular Cartilage Regeneration using Tissue Engineering Based on Multiphase Designs

  2019cites this paper
• Osteogenic differentiation of human bone marrow-derived mesenchymal stem cells is enhanced by an aragonite scaffold.

  2019cites this paper
• Osteochondral Tissue Engineering

  2018cites this paper
• Bilayered PLGA/PLGA-HAp Composite Scaffold for Osteochondral Tissue Engineering and Tissue Regeneration.

  2018cites this paper
• Agili-C implant promotes the regenerative capacity of articular cartilage defects in an ex vivo model

  2018cites this paper
• Large Animal Models for Osteochondral Regeneration.

  2018cites this paper
• Hierarchically structured seamless silk scaffolds for osteochondral interface tissue engineering.

  2018cites this paper
• Hyaluronic Acid.

  2018cites this paper
• Osteochondral Tissue Engineering: Translational Research and Turning Research into Products.

  2018cites this paper
• Generation of Cashmere Goats Carrying an EDAR Gene Mutant Using CRISPR-Cas9-Mediated Genome Editing

  2018cites this paper
• Enhancing Biological and Biomechanical Fixation of Osteochondral Scaffold: A Grand Challenge.

  2018cites this paper
• Emerging Technologies in Cartilage Repair

  2018cites this paper
• Osteochondral tissue repair in osteoarthritic joints: clinical challenges and opportunities in tissue engineering

  2018cites this paper
• Articular cartilage regeneration and tissue engineering models: a systematic review

  2018cites this paper
• Towards osteochondral regeneration with human bone marrow derived mesenchymal stromal cells in a functionalized hydrogel system

  2017influential citation
• Cell-Free Scaffolds for the Treatment of Chondral and Osteochondral Lesions

  2017cites this paper
• Genetic variability of myostatin and prolactin genes in popular goat breeds in Egypt

  2017cites this paper
• Osteochondral Repair Using a Hybrid Implant Composed of Stem Cells and Biomaterial

  2017cites this paper
• Pre-clinical and clinical management of osteochondral lesions

  2017cites this paper
• The Application of Nanotechnology for Implant Drug Release

  2016cites this paper
• Autologous tissue transplantations for osteochondral repair.

  2016cites this paper
• Effect of insulin-like growth factor-1 and hyaluronic acid in experimentally produced osteochondral defects in rats

  2016cites this paper
• A novel aragonite-based scaffold for osteochondral regeneration: early experience on human implants and technical developments.

  2016cites this paper
• Current Strategies in Osteochondral Repair with Biomaterial Scaffold

  2016cites this paper
• Cartilage Repair: Scaffolding

  2016cites this paper
• Recent Advances in Cartilage Repair (ICL 3)

  2016cites this paper
• Biomimetic strategies for engineering composite tissues.

  2016cites this paper
• A Review of Major Animal Models Relevant to Contemporary Orthopaedic Repair of the Appendicular Skeleton in Humans (Part 1: healing in the presence of bone defects, non-union and inter-current disease)

  2016cites this paper
• The osteochondral interface as a gradient tissue: from development to the fabrication of gradient scaffolds for regenerative medicine.

  2015cites this paper
• Three-dimensional Stem Cell Aggregates for Cartilage Tissue Engineering

  2015cites this paper
• Biomedical Materials for Regenerating Bone Tissue Utilizing Marine Invertebrate

  2015influential citation
• Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system

  2015cites this paper
• A Road Map to Commercialization of Cartilage Therapy in the United States of America

  2015cites this paper
• Osteochondral regeneration with a novel aragonite-hyaluronate biphasic scaffold: up to 12-month follow-up study in a goat model

  2015influential citation
• Biomimetic biphasic scaffolds for osteochondral defect repair

  2015cites this paper
• Current concepts: tissue engineering and regenerative medicine applications in the ankle joint

  2014cites this paper
• Treatment of Large Knee Osteochondral Lesions With a Biomimetic Scaffold

  2014cites this paper
• Osteochondral Repair Using a Scaffold-Free Tissue-Engineered Construct Derived from Synovial Mesenchymal Stem Cells and a Hydroxyapatite-Based Artificial Bone

  2014cites this paper
• Bioinspired Scaffolds for Osteochondral Regeneration

  2014cites this paper
• Tissue Engineering of Skeletal Tissues

  2014cites this paper
• Scaffold-based regeneration of skeletal tissues to meet clinical challenges.

  2014cites this paper
• Osteochondral Tissue Engineering with Biphasic Scaffold: Current Strategies and Techniques

  2014cites this paper
• A one-step treatment for chondral and osteochondral knee defects: clinical results of a biomimetic scaffold implantation at 2 years of follow-up

  2014cites this paper
• Clinical results of multilayered biomaterials for osteochondral regeneration

  2014cites this paper
• Chronic posttraumatic cartilage lesion of the knee treated with an acellular osteochondral-regenerating implant: case history with rehabilitation guidelines.

  2014cites this paper