Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension

No abstract is available for this paper.

• Publication year

  2016

• Venue

  HYPERTENSION

• Publication date

  2016-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/HYPERTENSIONAHA.115.06123PMID 26693821PMCID PMC4713264
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Faculty Opinions recommendation of Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis.

  2018cited by this paper
• Correction: Corrigendum: KLF4-dependent phenotypic modulation of smooth muscle cells has a key role in atherosclerotic plaque pathogenesis

  2015cited by this paper
• KLF4 Dependent Phenotypic Modulation of SMCs Plays a Key Role in Atherosclerotic Plaque Pathogenesis

  2015cited by this paper
• Components of Hemodynamic Load and Cardiovascular Events: The Framingham Heart Study

  2015cited by this paper
• Endothelial cells contribute to generation of adult ventricular myocytes during cardiac homeostasis.

  2014cited by this paper
• CXCR6 Plays a Critical Role in Angiotensin II–Induced Renal Injury and Fibrosis

  2014cited by this paper
• Coronary adventitial cells are linked to perivascular cardiac fibrosis via TGFβ1 signaling in the mdx mouse model of Duchenne muscular dystrophy.

  2013cited by this paper
• Origin and function of myofibroblasts in kidney fibrosis

  2013cited by this paper
• Inflammation and Mechanical Stretch Promote Aortic Stiffening in Hypertension Through Activation of p38 Mitogen-Activated Protein Kinase

  2013cited by this paper
• Myocardial migration by fibroblast progenitor cells is blood pressure dependent in a model of angII myocardial fibrosis

  2012cited by this paper
• Identification of a Monocyte-Predisposed Hierarchy of Hematopoietic Progenitor Cells in the Adventitia of Postnatal Murine Aorta

  2012cited by this paper
• FGF regulates TGF-β signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression.

  2012cited by this paper
• The adventitia: a dynamic interface containing resident progenitor cells.

  2011cited by this paper
• Inhibition and Genetic Ablation of the B7/CD28 T-Cell Costimulation Axis Prevents Experimental Hypertension

  2010cited by this paper
• Arterial Stiffness and Cardiovascular Events: The Framingham Heart Study

  2010cited by this paper
• In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium

  2010cited by this paper
• NADPH Oxidase-4 Mediates Myofibroblast Activation and Fibrogenic Responses to Lung Injury

  2009cited by this paper
• A sonic hedgehog signaling domain in the arterial adventitia supports resident Sca1+ smooth muscle progenitor cells

  2008influential reference
• Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis

  2006cited by this paper
• Isolation of “Side Population” Progenitor Cells From Healthy Arteries of Adult Mice

  2005cited by this paper
• The Chemokine Receptor CCR7 Activates in Dendritic Cells Two Signaling Modules That Independently Regulate Chemotaxis and Migratory Speed1

  2005cited by this paper
• Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis.

  2004cited by this paper
• Abundant progenitor cells in the adventitia contribute to atherosclerosis of vein grafts in ApoE-deficient mice.

  2004cited by this paper
• 6-C-kine (SLC), a Lymphocyte Adhesion-triggering Chemokine Expressed by High Endothelium, Is an Agonist for the MIP-3β Receptor CCR7

  1998cited by this paper
• Circulating Fibrocytes Define a New Leukocyte Subpopulation That Mediates Tissue Repair

  1994cited by this paper
• Stimulation of collagen synthesis in fibroblast cultures by superoxide.

  1991cited by this paper

• The role of vascular aging, bone marrow and immune system in hypertension

  2026cites this paper
• Advanced technologies of artery-on-a-chip: a review of construction strategies and disease models

  2026cites this paper
• Growth Arrest of Thoracic Aortic Aneurysms in Aging Marfan Mice

  2025cites this paper
• Bridging aging, immunity, and atherosclerosis: novel insights into senescence-related genes

  2025cites this paper
• Short-term aircraft noise stress induces a fundamental metabolic shift in heart proteome and metabolome that bears the hallmarks of cardiovascular disease.

  2025cites this paper
• PVAT Adipocyte: Energizing, Modulating, and Structuring Vascular Function During Normotensive and Hypertensive States.

  2025cites this paper
• Harnessing iPSCs to Model Marfan Syndrome: Advancing Clinical Diagnosis and Drug Discovery

  2025cites this paper
• Multi-Scale Multi-Cell Computational Model of Inflammation-Mediated Aortic Remodeling in Hypertension

  2025cites this paper
• Smooth muscle cell phenotypic modulation during atherosclerosis.

  2025cites this paper
• Fibroblast-Specific Loss of TGF-β Signaling Mediates Lipomatous Metaplasia in the Infarcted Heart.

  2025cites this paper
• Chronic Pod-Mod E-Cigarette Aerosol Exposure Induces Aortic Dysfunction in Hypercholesterolemic Mice: Role of Oxidative Stress and Inflammation.

  2025cites this paper
• KLF4 in smooth muscle cell-derived progenitor cells is essential for angiotensin II-induced cardiac inflammation and fibrosis

  2024cites this paper
• Multiscale computational modeling of arterial micromechanics: A review

  2024cites this paper
• Cardiac and perivascular myofibroblasts, matrifibrocytes, and immune fibrocytes in hypertension; commonalities and differences with myocardial infarction and other cardiovascular diseases.

  2024cites this paper
• Arterial Stiffness: From Basic Primers to Integrative Physiology.

  2024cites this paper
• Aortic Cellular Heterogeneity in Health and Disease: Novel Insights Into Aortic Diseases From Single-Cell RNA Transcriptomic Data Sets

  2024cites this paper
• Astragali Radix-Angelicae Sinensis Radix inhibits the activation of vascular adventitial fibroblasts and vascular intimal proliferation by regulating the TGF-β1/Smad2/3 pathway.

  2024cites this paper
• Resting Heart Rate Mediates the Association Between Circulating Neutrophil Count and Arterial Stiffness Progression: The Kailuan Study

  2024cites this paper
• Management of arterial hypertension in patients with peripheral arterial disease.

  2024cites this paper
• Transcriptome analysis of the aortic coarctation area

  2024cites this paper
• The Role of Progenitor Cells in the Pathogenesis of Arteriosclerosis

  2024cites this paper
• Circulating fibrocyte levels correlate with left ventricular mass in middle-aged healthy adults without hypertension

  2024cites this paper
• The Potential Mechanisms of Catechins in Tea for Anti-Hypertension: An Integration of Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation

  2024cites this paper
• Discovery of an embryonically derived bipotent population of endothelial-macrophage progenitor cells in postnatal aorta

  2024cites this paper
• Vascular remodelling in cardiovascular diseases: hypertension, oxidation, and inflammation.

  2024cites this paper
• Biomechanical dysregulation of SGK-1 dependent aortic pathologic markers in hypertension

  2024cites this paper
• The many roles of cathepsins in restenosis

  2024cites this paper
• The Pathogenesis and Impact of Arterial Stiffening in Hypertension The 2023 John H. Laragh Research Award.

  2024cites this paper
• Immune and inflammatory mechanisms in hypertension

  2024cites this paper
• Angiotensin II Type 1A Receptor Expressed in Smooth Muscle Cells is Required for Hypertensive Vascular Remodeling in Mice Infused With Angiotensin II

  2023cites this paper
• Serum Sema7A is increased in patients with acute aortic dissection

  2023cites this paper
• Emerging evidence for a cardiovascular protective effect of concentrated Japanese plum juice

  2023cites this paper
• Telocytes/CD34+ Stromal Cells in the Normal, Hyperplastic, and Adenomatous Human Parathyroid Glands

  2023cites this paper
• Hibiscus attenuates renovascular hypertension–induced aortic remodeling dose dependently: the oxidative stress role and Ang II/cyclophilin A/ERK1/2 signaling

  2023cites this paper
• Infused juice concentrate of Japanese plum Prunus mume attenuates inflammatory vascular remodeling in a mouse model of hypertension induced by angiotensin II

  2023cites this paper
• Advances in mechanical biomarkers

  2023cites this paper
• Mapping the unicellular transcriptome of the ascending thoracic aorta to changes in mechanosensing and mechanoadaptation during aging

  2022cites this paper
• How vascular smooth muscle cell phenotype switching contributes to vascular disease

  2022cites this paper
• The Adventitia in Arterial Development, Remodeling, and Hypertension.

  2022cites this paper
• Mammalian organ regeneration in spiny mice

  2022cites this paper
• Vascular Stem/Progenitor Cells in Vessel Injury and Repair

  2022cites this paper
• The age, NT-proBNP, and Ejection Fraction Score as a Novel Predictor of Clinical Outcomes in CAD Patients After PCI

  2022cites this paper
• Mediterranean G6PD variant rats are protected from Angiotensin II-induced hypertension and kidney damage, but not from inflammation and arterial stiffness.

  2022cites this paper
• Synthesis of multidimensional pathophysiological process leading to type A aortic dissection: a narrative review

  2021cites this paper
• Diet alters age-related remodeling of aortic collagen in mice susceptible to atherosclerosis.

  2021cites this paper
• Effects of Angiotensin II type I receptor shRNA on blood pressure and left ventricular remodeling in spontaneously hypertensive rats

  2021cites this paper
• Aortic carboxypeptidase-like protein regulates vascular adventitial progenitor and fibroblast differentiation through myocardin related transcription factor A

  2021cites this paper
• Heterogeneous subpopulations of adventitial progenitor cells regulate vascular homeostasis and pathological vascular remodeling.

  2021cites this paper
• Age and Sex Dependency of Thoracic Aortopathy in a Mouse Model of Marfan Syndrome.

  2021cites this paper
• Effects of Angiotensin II type I receptor shRNA on blood pressure and left 3 ventricular remodeling in spontaneously hypertensive rats

  2021cites this paper
• Discovery of an embryonically derived bipotent population of endothelial-macrophage progenitor cells in postnatal aorta

  2021cites this paper
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  2020cites this paper
• Ageing and atherosclerosis: vascular intrinsic and extrinsic factors and potential role of IL-6

  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• Vascular Extracellular Matrix Remodeling and Hypertension

  2020cites this paper
• The application of big data to cardiovascular disease: paths to precision medicine.

  2020cites this paper
• Cell signaling model for arterial mechanobiology

  2020cites this paper
• Ion Channels and Vascular Diseases.

  2019cites this paper
• PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling—Brief Report

  2019cites this paper
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  2019cites this paper
• The Role of Vascular Smooth Muscle Cells in Arterial Remodeling: Focus on Calcification-Related Processes

  2019cites this paper
• (2016). Discovering cardiac pericytes biology: From physiopathological mechanisms to potential therapeutic applications in ischemic heart disease. Vascular Pharmacology 86 , 53-63.

  2019cites this paper
• Intracellular retention of mutant lysyl oxidase leads to aortic dilation in response to increased hemodynamic stress.

  2019cites this paper
• Vasculogenic properties of adventitial Sca-1+CD45+ progenitor cells in mice: a potential source of vasa vasorum in atherosclerosis

  2019cites this paper
• Investigating the roles of distinct macrophage phenotypes in cardiovascular disease

  2019influential citation
• Role of Complement-Related Inflammation and Vascular Dysfunction in Hypertension

  2019cites this paper
• Dysregulation of IL-33/ST2 signaling and myocardial periarteriolar fibrosis.

  2019cites this paper
• Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications.

  2019cites this paper
• Hypertension Induced Morphological and Physiological Changes in Cells of the Arterial Wall

  2018cites this paper
• 7 – Inflammation and Immunity in Hypertension

  2018cites this paper
• Vascular Fibrosis and Disease

  2018cites this paper
• An update on clonality: what smooth muscle cell type makes up the atherosclerotic plaque?

  2018cites this paper
• Multiphoton Imaging of Collagen, Elastin, and Calcification in Intact Soft‐Tissue Samples

  2018cites this paper
• EndMT: A promising and controversial field.

  2018cites this paper
• Arterial hypertension after age 65: from epidemiology and pathophysiology to therapy Do we know where we stand?

  2018cites this paper
• Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology.

  2018cites this paper
• Periadventitial local drug delivery to target restenosis.

  2017cites this paper
• Cyp 2 c 44 gene disruption is associated with increased hematopoietic stem cells : implication in chronic hypoxia-induced pulmonary hypertension

  2017cites this paper
• Vascular Progenitors and Smooth Muscle Cells Chicken and Egg?

  2017cites this paper
• The Vascular Wall: a Plastic Hub of Activity in Cardiovascular Homeostasis and Disease

  2017cites this paper
• Adventitial Sca1+ Cells Transduced With ETV2 Are Committed to the Endothelial Fate and Improve Vascular Remodeling After Injury

  2017cites this paper
• Inflammation and fibrosis.

  2017cites this paper
• Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular Progenitor Cells in the Adventitia Regulated by Klf4

  2017cites this paper
• Caveolin-1 Deletion Prevents Hypertensive Vascular Remodeling Induced by Angiotensin II

  2017cites this paper
• Tracking Adventitial Fibroblast Contribution to Disease: A Review of Current Methods to Identify Resident Fibroblasts.

  2017cites this paper
• Longitudinal Study of Hypertensive Subjects With Type 2 Diabetes Mellitus: Overall and Cardiovascular Risk

  2017cites this paper
• Cyp2c44 gene disruption is associated with increased hematopoietic stem cells: implication in chronic hypoxia-induced pulmonary hypertension.

  2017cites this paper
• Phenotypical characterization of aortic rupture in Friesian horses

  2016cites this paper
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  2016cites this paper
• Progenitor Cells, Bone Marrow-Derived Fibrocytes and Endothelial-to-Mesenchymal Transition: New Players in Vascular Fibrosis.

  2016cites this paper
• Discovering cardiac pericyte biology: From physiopathological mechanisms to potential therapeutic applications in ischemic heart disease.

  2016cites this paper
• Is Hypertension a Bone Marrow Disease?

  2016cites this paper
• ATVB IN FOCUS: Mechanics, Matrix, Bioengineering, and the Cardiovascular System: Damage to Repair

  year unknowncites this paper