Intima media thickness of carotid arteries is reduced in heterozygous carriers of the Gly972Arg variant in the insulin receptor substrate‐1 gene

No abstract is available for this paper.

• Publication year

  2003

• Venue

  European Journal of Clinical Investigation

• Publication date

  2003-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1046/j.1365-2362.2003.01113.xPMID 12588284
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Amino acid polymorphism Gly 972 Arg in IRS-1 is not associated to lower clamp-derived insulin sensitivity in young healthy first degree relatives of patients with type 2 diabetes.

  2009cited by this paper
• Insulin and Insulin-Like Growth Factor I Receptors: Similarities and Differences in Signal Transduction

  2004cited by this paper
• Molecular scanning of the insulin receptor substrate-1 (IRS-1) gene in Japanese patients with NIDDM: identification of five novel polymorphisms

  2004cited by this paper
• Peroxisome proliferator-activated receptor-gamma coactivator-1 gene locus: associations with obesity indices in middle-aged women.

  2002cited by this paper
• Peroxisome Proliferator-Activated Receptor-γ Coactivator-1 Gene Locus Associations With Obesity Indices in Middle-Aged Women

  2002cited by this paper
• Use of carotid ultrasound to stratify risk.

  2001cited by this paper
• A common polymorphism in the promoter of UCP2 is associated with decreased risk of obesity in middle-aged humans

  2001cited by this paper
• The G972R variant of the Insulin Receptor Substrate-1 (IRS-1) gene, body fat distribution and insulin-resistance

  2001cited by this paper
• Effects of Blood Pressure, Smoking, and Their Interaction on Carotid Artery Structure and Function

  2001cited by this paper
• Increased Expression of the Sterol Regulatory Element-binding Protein-1 Gene in Insulin Receptor Substrate-2−/−Mouse Liver*

  2001cited by this paper
• Two novel mutations in the lipoprotein lipase gene in a family with marked hypertriglyceridemia in heterozygous carriers. Potential interaction with the polymorphic marker D1S104 on chromosome 1q21-q23.

  2000cited by this paper
• IRS-1 variant: A new risk factor for coronary artery disease?

  2000cited by this paper
• Common carotid artery intima-media thickness and brain infarction : the Etude du Profil Génétique de l'Infarctus Cérébral (GENIC) case-control study. The GENIC Investigators.

  2000cited by this paper
• Insulin resistance syndrome predicts the risk of coronary heart disease and stroke in healthy middle-aged men: the 22-year follow-up results of the Helsinki Policemen Study.

  2000cited by this paper
• Carotid wall thickness is predictive of incident clinical stroke: the Atherosclerosis Risk in Communities (ARIC) study.

  2000cited by this paper
• CAROTID-ARTERY INTIMA AND MEDIA THICKNESS AS A RISK FACTOR FOR MYOCARDIAL INFARCTION AND STROKE IN OLDER ADULTS

  2000cited by this paper
• Two novel mutations in the lipoprotein lipase gene in a family with marked hypertriglyceridemia in heterozygous carriers : potential interaction with the polymorphic marker D 1 S 104 on chromosome 1 q 21 – q 23

  2000cited by this paper
• Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group.

  1999cited by this paper
• Carotid plaque, intima media thickness, cardiovascular risk factors, and prevalent cardiovascular disease in men and women: the British Regional Heart Study.

  1999cited by this paper
• A common mutation of the insulin receptor substrate-1 gene is a risk factor for coronary artery disease.

  1999cited by this paper
• Insulin Sensitivity Is Not Affected by Mutation of Codon 972 of the Human IRS-1 Gene

  1999cited by this paper
• Insulin resistance and classic risk factors in type 2 diabetic patients with different subtypes of ischemic stroke.

  1999cited by this paper
• Common carotid intima-media thickness and risk of stroke and myocardial infarction: the Rotterdam Study.

  1997cited by this paper
• UKPDS 19: heterogeneity in NIDDM: separate contributions of IRS-1 and beta 3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations. UK Prospective Diabetes Study.

  1996cited by this paper
• Hyperinsulinaemia, insulin resistance, microalbuminuria and the risk of coronary heart disease.

  1996cited by this paper
• The normal menopause transition: an overview.

  1996cited by this paper
• UKPDS 19: Heterogeneity in NIDDM: separate contributions of IRS-1 and b3-adrenergic-receptor mutations to insulin resistance and obesity respectively with no evidence for glycogen synthase gene mutations

  1996cited by this paper
• Insulin action in man.

  1996cited by this paper
• Insulin resistance and coronary heart disease

  1996cited by this paper
• Codon 972 polymorphism in the insulin receptor substrate-1 gene, obesity, and risk of noninsulin-dependent diabetes mellitus.

  1996cited by this paper
• Human Insulin Receptor Substrate‐1: Variant Sequences in Familial Non‐insulin‐dependent Diabetes Mellitus

  1996cited by this paper
• Diverse signaling pathways in the cellular actions of insulin.

  1996cited by this paper
• No Association Between The Gly971 Arg Variant of the Insulin Receptor Substrate 1 Gene and NIDDM in the Taiwanese Population

  1996cited by this paper
• Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.

  1995cited by this paper
• Insulin receptor substrate-1 gene mutations in NIDDM; implications for the study of polygenic disease

  1995cited by this paper
• Insulin receptor substrate-1 variants in non-insulin-dependent diabetes.

  1994cited by this paper
• Relation of components of insulin resistance syndrome to coronary disease risk.

  1994cited by this paper
• Variant sequences of insulin receptor substrate-1 in patients with noninsulin-dependent diabetes mellitus.

  1994cited by this paper
• Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.

  1993cited by this paper
• Insulin receptor substrate (IRS-1) gene polymorphisms in French NIDDM families.

  1993cited by this paper
• Human Skeletal Muscle Insulin Receptor Substrate-1: Characterization of the cDNA, Gene, and Chromosomal Localization

  1993cited by this paper
• Rationale and design for the Asymptomatic Carotid Artery Plaque Study (ACAPS). The ACAPS Group.

  1992cited by this paper
• Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man

  1985cited by this paper

• A REVIEW ON SERUM MARKERS AND GENETICS OF ENDOTHELIAL DYSFUNCTION

  2020cites this paper
• Endothelial Dysfunction in Type 2 Diabetes Mellitus

  2015cites this paper
• Genetics of Atherosclerotic Cardiovascular Disease

  2013cites this paper
• Allelic variants of insulin receptor substrate-1 gene in Egyptian women with polycystic ovary syndrome

  2012cites this paper
• Authors’ response: „Carotid intima-media thickness, thrombin and atherosclersosis“

  2011cites this paper
• Relationship between thrombin generation and carotid intima-media thickness.

  2010cites this paper
• Genes and Nutrition

  2010cites this paper
• Are plasma VEGF and its soluble receptor sFlt-1 atherogenic risk factors? Cross-sectional data from the SAPHIR study.

  2009cites this paper
• Analysis of the Association of Preeclampsia with Polymorphisms of the INS, INSR and IRS1 Genes in Mexican Women

  2008cites this paper
• Comparison of different definitions of the metabolic syndrome

  2007cites this paper
• An association between a common variant (G972R) in the IRS-1 gene and sex hormone levels in post-menopausal breast cancer survivors

  2006cites this paper
• Prediction of Cardiovascular Morbidity and Mortality: Comparison of the Internal Carotid Artery Resistive Index With the Common Carotid Artery Intima-Media Thickness

  2006cites this paper
• Plasma Adiponectin Levels and Sonographic Phenotypes of Subclinical Carotid Artery Atherosclerosis: Data From the SAPHIR Study

  2005cites this paper
• The Metabolic Syndrome Is a Stronger Risk Factor for Early Carotid Atherosclerosis in Women Than in Men

  2005cites this paper
• Lack of association of the Gly972Arg mutation of the insulin receptor substrate‐1 gene with coronary artery disease in the Austrian population

  2004cites this paper
• Increased Insulin Receptor Substrate 1 Serine Phosphorylation and Stress-Activated Protein Kinase/c-Jun N-Terminal Kinase Activation Associated With Vascular Insulin Resistance in Spontaneously Hypertensive Rats

  2004cites this paper
• Resistance in Spontaneously Hypertensive Rats Protein Kinase / c-Jun N-Terminal Kinase Activation Associated With Vascular Insulin Increased Insulin Receptor Substrate 1 Serine Phosphorylation and Stress-Activated

  2004cites this paper