[Genetic background of sex determination and gonadal development disorders].

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Endokrynologia Polska

• Publication date

  2008-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 19347816
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling.

  2008cited by this paper
• Sex determination and gonadal development in mammals.

  2007cited by this paper
• Genetyczne mechanizmy determinacji plci i roznicowania gonad ssakow

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• SOX9 Regulates Prostaglandin D Synthase Gene Transcription in Vivo to Ensure Testis Development*

  2007cited by this paper
• WNT4 and RSPO1 Are Not Involved in a Case of Male-to-Female Sex Reversal with Partial Duplication of 1p

  2007cited by this paper
• Sry and the hesitant beginnings of male development.

  2007cited by this paper
• R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6

  2007cited by this paper
• Sex determination and sex reversal.

  2006cited by this paper
• Expression profiling of purified mouse gonadal somatic cells during the critical time window of sex determination reveals novel candidate genes for human sexual dysgenesis syndromes.

  2006cited by this paper
• Homozygous Inactivation of Sox9 Causes Complete XY Sex Reversal in Mice1

  2006cited by this paper
• Fgf9 and Wnt4 Act as Antagonistic Signals to Regulate Mammalian Sex Determination

  2006influential reference
• R-spondin1 is essential in sex determination, skin differentiation and malignancy

  2006cited by this paper
• Silencing of unsynapsed meiotic chromosomes in the mouse

  2005cited by this paper
• The pathway to femaleness: current knowledge on embryonic development of the ovary.

  2005cited by this paper
• Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination.

  2005influential reference
• Foxl2 is required for commitment to ovary differentiation.

  2005cited by this paper
• Gene expression during sex determination reveals a robust female genetic program at the onset of ovarian development.

  2005cited by this paper
• One tissue, two fates: molecular genetic events that underlie testis versus ovary development

  2004cited by this paper
• Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development.

  2004cited by this paper
• The endless quest for sex determination genes

  2004influential reference
• Functional analysis of Sox8 and Sox9 during sex determination in the mouse

  2004cited by this paper
• Insights into the physiological role of WT1 from studies of genetically modified mice.

  2004influential reference
• Wnt4 is required for proper male as well as female sexual development.

  2004influential reference
• Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis

  2004cited by this paper
• A WNT4 mutation associated with Müllerian-duct regression and virilization in a 46,XX woman.

  2004cited by this paper
• ATRX and sex differentiation.

  2004influential reference
• A microdeletion in the ligand binding domain of human steroidogenic factor 1 causes XY sex reversal without adrenal insufficiency.

  2004cited by this paper
• The effects of estrogen on the expression of genes underlying the differentiation of somatic cells in the murine gonad.

  2004cited by this paper
• Disrupted gonadogenesis and male-to-female sex reversal in Pod1 knockout mice

  2004cited by this paper
• Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function.

  2004influential reference
• Porcine SRY Promoter Is a Target for Steroidogenic Factor 11

  2003cited by this paper
• Pdgfr-alpha mediates testis cord organization and fetal Leydig cell development in the XY gonad.

  2003influential reference
• Sex determination: the fishy tale of Dmrt1.

  2003cited by this paper
• Synergistic Cooperation between the β-Catenin Signaling Pathway and Steroidogenic Factor 1 in the Activation of the Mullerian Inhibiting Substance Type II Receptor*

  2003cited by this paper
• The complex life of WT1

  2003cited by this paper
• Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad

  2003cited by this paper
• A SOX9 Defect of Calmodulin-dependent Nuclear Import in Campomelic Dysplasia/Autosomal Sex Reversal*

  2003cited by this paper
• Gonad development in Drash and Frasier syndromes depends on WT1 mutations.

  2003cited by this paper
• Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early-acting gene in vertebrate ovarian development.

  2003cited by this paper
• Regulation of the phenotype of ovarian somatic cells by estrogen.

  2003cited by this paper
• Turning on the male – SRY, SOX9 and sex determination in mammals

  2003cited by this paper
• Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans

  2002influential reference
• Steroidogenic factor 1: an essential mediator of endocrine development.

  2002cited by this paper
• Gonadal determination and adrenal development are regulated by the orphan nuclear receptor steroidogenic factor-1, in a dose-dependent manner.

  2002cited by this paper
• Estrogen regulates development of the somatic cell phenotype in the eutherian ovary

  2002cited by this paper
• Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis.

  2002influential reference
• A nuclear export signal within the high mobility group domain regulates the nucleocytoplasmic translocation of SOX9 during sexual determination

  2002cited by this paper
• A 11.7-kb deletion triggers intersexuality and polledness in goats

  2001cited by this paper
• Steroidogenic Factor-1 Contributes to the Cyclic-Adenosine Monophosphate Down-Regulation of Human SRY Gene Expression1

  2001cited by this paper
• Sox9 induces testis development in XX transgenic mice

  2001cited by this paper
• Compound Effects of Point Mutations Causing Campomelic Dysplasia/Autosomal Sex Reversal upon SOX9 Structure, Nuclear Transport, DNA Binding, and Transcriptional Activation*

  2001cited by this paper
• FIGalpha, a germ cell-specific transcription factor required for ovarian follicle formation.

  2000cited by this paper
• Genetics of sex determination: exceptions that prove the rule.

  2000cited by this paper
• A novel mutation of desert hedgehog in a patient with 46,XY partial gonadal dysgenesis accompanied by minifascicular neuropathy.

  2000cited by this paper
• Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes.

  2000cited by this paper
• Apparently normal ovarian differentiation in a prepubertal girl with transcriptionally inactive steroidogenic factor 1 (NR5A1/SF-1) and adrenocortical insufficiency.

  2000cited by this paper
• A new submicroscopic deletion that refines the 9p region for sex reversal.

  2000cited by this paper
• Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development.

  1999cited by this paper
• Autosomal XX sex reversal caused by duplication of SOX9.

  1999cited by this paper
• A mutation in the gene encoding steroidogenic factor-1 causes XY sex reversal and adrenal failure in humans

  1999cited by this paper
• Female development in mammals is regulated by Wnt-4 signalling

  1999cited by this paper
• Frasier syndrome is caused by defective alternative splicing of WT1 leading to an altered ratio of WT1 +/-KTS splice isoforms.

  1998cited by this paper
• Evidence for evolutionary conservation of sex-determining genes

  1998cited by this paper
• Dax1 antagonizes Sry action in mammalian sex determination

  1998cited by this paper
• A gene involved in XY sex reversal is located on chromosome 9, distal to marker D9S1779.

  1998cited by this paper
• Deletions of distal 9p associated with 46,XY male to female sex reversal: definition of the breakpoints at 9p23.3-p24.1.

  1997cited by this paper
• The Wilms' tumor gene WT1 can regulate genes involved in sex determination and differentiation: SRY, Müllerian-inhibiting substance, and the androgen receptor.

  1997cited by this paper
• Polymerase chain reaction screening for Y chromosome microdeletions: a first step towards the diagnosis of genetically-determined spermatogenic failure in men.

  1996cited by this paper
• Clinical, biochemical, and genetic findings in a large pedigree of male and female patients with 5 alpha-reductase 2 deficiency.

  1996cited by this paper
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  1995cited by this paper
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  1995cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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  1993cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1989cited by this paper
• Meiosis and differentiation of mouse germ cells.

  1984cited by this paper
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  1984cited by this paper
• Cytogenetic recognition of chromosomal duplication [dup(1)(p31.4 leads to p22.1)] and the detection of three different alleles at the PGM1 locus.

  1981cited by this paper
• Cytogenetic recognition of chromosomal duplication [dup(l)(p31.4 ‐→ p22.1)] and the detection of three different alleles at the PGM1 locus

  1981cited by this paper
• Rat gonadal and ovarioan organogenesis with and without germ cells. An ultrastructural study.

  1975cited by this paper
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  1973cited by this paper
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  1971cited by this paper
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  1970cited by this paper

• Alternative splicing and its role in pathologies of the endocrine system.

  2011cites this paper
• Alternative splicing and its role in pathologies of the endocrine system Różnicowe składanie pierwotnego transkryptu w patologiach układu endokrynnego

  2011cites this paper