Anemia hemolítica como manifestación inicial de macroglobulinemia de Waldenström

Waldenström macroglobulinemia (WM) is a hematological malignancy with lymphoplasmacytic proliferation, monoclonal production of immunoglobulin M (IgM) and spinal infiltration. In Mexico, it has an incidence of 0.18%. This article presents the case of a 63-year-old boy with dyspnea, asthenia, weight loss, jaundice, pancytopenia, serum protein electrophoresis (SPEP) with Rouleaux and direct Coombs with cold autoantibodies. The protocol of autoimmune hemolytic anemia, bone marrow aspirate with Mott cells and some plasmatic and bone biopsy with abnormal plasma cells in 15%. Serum protein electrophoresis with hypergammaglobulinemia and monoclonal peak, immunofixation with IgM-l and immunofixation in urine for Bence Jones protein negative. It concludes with the diagnosis of WM. (Hosp Med Clin Manag. 2018;11:148-54) Corresponding author: Daniela Hernández-Islas, daniela.islas@outlook.com

• Publication year

  2018

• Venue

  Revista Hospital Medicine and Clinical Management

• Publication date

  2018-10-05

• Fields of study

  Medicine

• Identifiers
  DOI 10.24875/HMCM.18000133
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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