Molecular dynamics and circular dichroism studies of human and rat C-peptides.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Molecular Graphics and Modelling

• Publication date

  2006-12-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.JMGM.2006.03.002PMID 16750642
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Conformational analysis of circular dichroism spectra of insulin, proinsulin and c-peptides by non-linear regression.

  2009cited by this paper
• Structural changes involved in the folding of proinsulin.

  2009cited by this paper
• Molecular parameters of C-peptide from bovine proinsulin.

  2009cited by this paper
• Molecular dynamics simulations of peptide-surface interactions.

  2005cited by this paper
• Molecular dynamics simulations of helical antimicrobial peptides in SDS micelles: what do point mutations achieve?

  2005cited by this paper
• Solution structure of human proinsulin C‐peptide

  2005cited by this paper
• The Proinsulin C-peptide—A Multirole Model

  2004cited by this paper
• BMC Bioinformatics BioMed Central Methodology article

  2004cited by this paper
• C‐peptide: new findings and therapeutic implications in diabetes

  2004cited by this paper
• UniProt: the Universal Protein knowledgebase

  2004cited by this paper
• C-peptide stimulates ERK1/2 and JNK MAP kinases via activation of protein kinase C in human renal tubular cells

  2004cited by this paper
• Two-dimensional conformation-dependent electrophoresis (2D-CDE) to separate DNA fragments containing unmatched bulge from complex DNA samples.

  2004cited by this paper
• GenBank: update

  2004cited by this paper
• C-peptide stimulates Na+, K+-ATPase via activation of ERK1/2 MAP kinases in human renal tubular cells

  2004cited by this paper
• Equilibrium structure and folding of a helix-forming peptide: circular dichroism measurements and replica-exchange molecular dynamics simulations.

  2004cited by this paper
• Multiple sequence alignment with the Clustal series of programs

  2003cited by this paper
• In Vitro Refolding of Human Proinsulin

  2003cited by this paper
• Acidic residues on the N-terminus of proinsulin C-Peptide are important for the folding of insulin precursor.

  2002cited by this paper
• Role of C-peptide in human physiology.

  2000cited by this paper
• Unordered structure of proinsulin C-peptide in aqueous solution and in the presence of lipid vesicles

  2000cited by this paper
• The Protein Data Bank

  2000cited by this paper
• NPS@: network protein sequence analysis.

  2000cited by this paper
• Specific binding of proinsulin C-peptide to human cell membranes.

  1999cited by this paper
• Predicted structural alterations in proinsulin during its interactions with prohormone convertases.

  1999cited by this paper
• Prevention of vascular and neural dysfunction in diabetic rats by C-peptide.

  1997cited by this paper
• A set of constructed type spectra for the practical estimation of peptide secondary structure from circular dichroism.

  1997cited by this paper
• Circular dichroism.

  1995cited by this paper
• Sequence requirements for proinsulin processing at the B-chain/C-peptide junction.

  1995cited by this paper
• [4] Circular dichroism

  1995cited by this paper
• Stabilization of alpha-helical structures in short peptides via end capping.

  1993cited by this paper
• Comparison of secondary structures of insulin and proinsulin by FTIR

  1993cited by this paper
• Evaluation of secondary structure of proteins from UV circular dichroism spectra using an unsupervised learning neural network.

  1993cited by this paper
• NMR and photo-CIDNP studies of human proinsulin and prohormone processing intermediates with application to endopeptidase recognition.

  1990cited by this paper
• Intraorganellar calcium and pH control proinsulin cleavage in the pancreatic β cell via two distinct site-specific endopeptidases

  1988cited by this paper
• Improved tools for biological sequence comparison.

  1988cited by this paper
• On the Role of the Proinsulin C-peptide

  1978cited by this paper
• Proinsulin and C-peptide: a review.

  1977cited by this paper
• Two-Point Calibration of Circular Dichrometer with d-10-Camphorsulfonic Acid

  1977cited by this paper
• Cell-free synthesis of rat preproinsulins: characterization and partial amino acid sequence determination.

  1976cited by this paper
• The conformational protential of porcine proinsulin C-peptide.

  1976cited by this paper
• Proinsulin: a proposed three-dimensional structure.

  1975cited by this paper
• Studies on polypeptides. V. Improved synthesis of human proinsulin C-peptide and its benzyloxycarbonyl derivative. Circular dichroism and immunological studies of human C-peptide.

  1975cited by this paper
• Insulin: The Structure in the Crystal and its Reflection in Chemistry and Biology by

  1972cited by this paper
• Insulin and Proinsulin Conformation in Solution

  1972cited by this paper
• Studies on human proinsulin. Isolation and amino acid sequence of the human pancreatic C-peptide.

  1971cited by this paper
• Proinsulin: Crystallization and preliminary x-ray diffraction studies.

  1970cited by this paper
• Secretion of Proinsulin C-Peptide by Pancreatic β Cells and its Circulation in Blood

  1969cited by this paper
• Insulin Biosynthesis: Evidence for a Precursor

  1967cited by this paper
• Methods in Enzymology , Vol

  1966cited by this paper
• Electronic Reprint Biological Crystallography the Protein Data Bank Biological Crystallography the Protein Data Bank

  year unknowncited by this paper

• Enhanced glucose regulation potential of C-peptide mimics.

  2025cites this paper
• Unlocking Insights into Folding, Structure, and Function of Proteins through Circular Dichroism Spectroscopy—A Short Review

  2023cites this paper
• Elucidation of a Copper Binding Site in Proinsulin C-peptide and Its Implications for Metal-Modulated Activity.

  2020cites this paper
• Is GPR146 really the receptor for proinsulin C-peptide?

  2020cites this paper
• Biological activity versus physiological function of proinsulin C-peptide

  2020cites this paper
• Unraveling the aggregation propensity of human insulin C‐peptide

  2017cites this paper
• A subdivided molecular architecture with separate features and stepwise emergence among proinsulin C-peptides.

  2014cites this paper
• Evidence for inhibitory autocrine effects of proinsulin C‐peptide on pancreatic β‐cell function and insulin secretion

  2014influential citation
• The structure, molecular interactions and bioactivities of proinsulin C-peptide correlate with a tripartite molecule

  2014cites this paper
• Sensitive and specific time-resolved fluorescence immunoassay of rat C-peptide for measuring hormone secretory and storage capacity of β-cells in vivo and in vitro.

  2013cites this paper
• [Pleiotropic action of proinsulin C-peptide].

  2012cites this paper
• Biological Significances, Diagnostic Values and Therapeutic Approach of Proinsulin Connecting Peptide

  2011cites this paper
• Mass spectrometric characterization and activity of zinc-activated proinsulin C-peptide and C-peptide mutants.

  2010cites this paper
• Structural features of proinsulin C‐peptide oligomeric and amyloid states

  2010cites this paper
• The use of circular dichroism spectroscopy to study protein folding, form and function

  2009cites this paper