Cognitive dysfunction in non-demented patients with Parkinson's disease

I. Zalonis,F. Christidi,C. Zournas,A. Ilias,E. Kararizou,M. Anagnostouli,Elissavet Andreadou,D. Vassilopoulos

Published 2010 in Annals of General Psychiatry

ABSTRACT

Materials and methods One hundred and thirty-nine non-demented PD patients (82♂/57♀; age:62.3 ± 9.2, education:11.0 ± 3.7, disease’s duration:12.2 ± 7.3), diagnosed between 19902000 according to explicit and generally accepted criteria based on neurological clinical examination, and 139 well-matched healthy controls (HC; 82♂/57♀; age:62.4 ± 9.2, education:11.0 ± 3.5) were included in the study. Both groups underwent a comprehensive series of neuropsychological tests, covered the cognitive domains of attention, learning and memory, language and academic skills, perceptual, constructional and visuomotor dexterities, verbal and visual reasoning, and executive functions. Patients did not show motor disabilities severe enough to interfere with nps performance.

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