Stimulation of gastrin-CCKB receptor promotes migration of gastric AGS cells via multiple paracrine pathways.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  American Journal of Physiology - Gastrointestinal and Liver Physiology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPGI.00300.2002PMID 12488236
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Identification of plasminogen activator inhibitor-2 as a gastrin-regulated gene: Role of Rho GTPase and menin.

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• Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry

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• Activated Release of Membrane-anchored TGF-ct in the Absence of Cytosol

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• Involvement of Phosphatidylinositol 3-Kinase and Mitogen-activated Protein Kinases in Glycine-extended Gastrin-induced Dissociation and Migration of Gastric Epithelial Cells*

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• Measurement of MAP kinase activation by flow cytometry using phospho-specific antibodies to MEK and ERK: potential for pharmacodynamic monitoring of signal transduction inhibitors.

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• Glycine-extended gastrin synergizes with gastrin 17 to stimulate acid secretion in gastrin-deficient mice.

  2000cited by this paper
• Induction and regulation of epithelial-mesenchymal transitions.

  2000cited by this paper
• Induction of Heparin Binding Epidermal Growth Factor-like Growth Factor and Amphiregulin mRNAs by Gastrin in the Rat Stomach

  2000cited by this paper
• Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation.

  2000cited by this paper
• Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer.

  2000influential reference
• The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor*

  2000cited by this paper
• The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor.

  2000cited by this paper
• Cholecystokinin-B/gastrin receptors enhance wound healing in the rat gastric mucosa.

  2000cited by this paper
• The current state of two‐dimensional electrophoresis with immobilized pH gradients

  2000cited by this paper
• Gastrin induces heparin-binding epidermal growth factor-like growth factor in rat gastric epithelial cells transfected with gastrin receptor.

  1999cited by this paper
• Identification of proteins by matrix-assisted laser desorption/ionization mass spectrometry using peptide and fragment ion masses.

  1999cited by this paper
• EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF

  1999cited by this paper
• Regulation of tyrosine kinase cascades by G-protein-coupled receptors.

  1999cited by this paper
• Metalloprotease-mediated ligand release regulates autocrine signaling through the epidermal growth factor receptor.

  1999cited by this paper
• Regenerating gene protein may mediate gastric mucosal proliferation induced by hypergastrinemia in rats.

  1998cited by this paper
• Comparison of the signal transduction pathways activated by gastrin in enterochromaffin-like and parietal cells.

  1998cited by this paper
• Extracellular calcium influx stimulates metalloproteinase cleavage and secretion of heparin‐binding EGF‐like growth factor independently of protein kinase C

  1998influential reference
• Signal characteristics of G protein‐transactivated EGF receptor

  1997cited by this paper
• CCK-B receptors produce similar signals but have opposite growth effects in CHO and Swiss 3T3 cells.

  1997cited by this paper
• Induction of heparin binding epidermal growth factor-like growth factor and amphiregulin mRNAs by gastrin in the rat stomach.

  1997cited by this paper
• Cholecystokinin (CCK) regulates somatostatin secretion through both the CCK‐A and CCK‐B/gastrin receptors in sheep

  1997cited by this paper
• Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

  1996cited by this paper
• Phorbol ester induces the rapid processing of cell surface heparin-binding EGF-like growth factor: conversion from juxtacrine to paracrine growth factor activity.

  1995influential reference
• Production of basic fibroblast growth factor by gastric carcinoid tumors and their putative cells of origin.

  1994cited by this paper
• CCKA and CCKB receptors are expressed in small cell lung cancer lines and mediate Ca2+ mobilization and clonal growth.

  1993cited by this paper
• Activated release of membrane-anchored TGF-alpha in the absence of cytosol

  1993cited by this paper
• Molecular aspects of mesenchymal-epithelial interactions.

  1993cited by this paper
• Improved staining of proteins in polyacrylamide gels including isoelectric focusing gels with clear background at nanogram sensitivity using Coomassie Brilliant Blue G‐250 and R‐250

  1988cited by this paper
• How does gastrin act to stimulate oxyntic cell secretion

  1987cited by this paper

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  2020cites this paper
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  2020cites this paper
• Chemerin acts via CMKLR1 and GPR1 to stimulate migration and invasion of gastric cancer cells: putative role of decreased TIMP-1 and TIMP-2

  2019cites this paper
• Biomarkers of the effect of gastrin on Barrett's oesophagus

  2018cites this paper
• Cell cycle dependent expression of the CCK2 receptor by gastrointestinal myofibroblasts: putative role in determining cell migration

  2017cites this paper
• Insights into gastric neuroendocrine tumors burden

  2017cites this paper
• Gastrin activates autophagy and increases migration and survival of gastric adenocarcinoma cells

  2017cites this paper
• Gastrin-induced miR-222 promotes gastric tumor development by suppressing p27kip1

  2016cites this paper
• Gastrokine 1 inhibits gastrin-induced cell proliferation

  2016cites this paper
• Gastrin stimulates MMP-1 expression in gastric epithelial cells: putative role in gastric epithelial cell migration.

  2015cites this paper
• Evaluation of a Nonpeptidic Ligand for Imaging of Cholecystokinin 2 Receptor–Expressing Cancers

  2015cites this paper
• CMKLR1 and GPR1 mediate chemerin signaling through the RhoA/ROCK pathway.

  2015cites this paper
• Anti-Gastrins Antiserum Combined with Lowered Dosage Cytotoxic Drugs to Inhibit the Growth of Human Gastric Cancer SGC7901 Cells in Nude Mice

  2015cites this paper
• The Chemerin Receptor GPR1 Signals Through a RhoA/ROCK Pathway and Contributes to Glucose Homeostasis in Obese Mice

  2015cites this paper
• A network map of the gastrin signaling pathway

  2014cites this paper
• Increased Expression of Chemerin in Squamous Esophageal Cancer Myofibroblasts and Role in Recruitment of Mesenchymal Stromal Cells

  2014cites this paper
• Salt-Inducible Kinase 1 (SIK1) Is Induced by Gastrin and Inhibits Migration of Gastric Adenocarcinoma Cells

  2014cites this paper
• The Role of Proteasome Beta Subunits in Gastrin-Mediated Transcription of Plasminogen Activator Inhibitor-2 and Regenerating Protein1

  2013cites this paper
• Comparative proteomic analysis implicates eEF2 as a novel target of PI3Kγ in the MDA-MB-231 metastatic breast cancer cell line

  2013cites this paper
• Gastrin-induced proliferation involves MEK partner 1 (MP1)

  2013cites this paper
• Comparative proteomic analysis implicates eEF 2 as a novel target of PI 3 Kγ in the MDA-MB-231 metastatic breast cancer cell line

  2013cites this paper
• The C-terminal flanking peptide of progastrin induces gastric cell apoptosis and stimulates colonic cell division in vivo.

  2013cites this paper
• Somatic Mutations in CCK2R Alter Receptor Activity that Promote Oncogenic Phenotypes

  2012cites this paper
• Helicobacter pylori CagL dependent induction of gastrin expression via a novel αvβ5-integrin–integrin linked kinase signalling complex

  2012cites this paper
• Immunotherapy for gastric premalignant lesions and cancer.

  2012cites this paper
• NIR-activated content release from plasmon resonant liposomes for probing single-cell responses.

  2012cites this paper
• Dissecting the First Transcriptional Divergence During Human Embryonic Development

  2011cites this paper
• Role of AMP-18 in oral mucositis.

  2011cites this paper
• Gastrin increases its own synthesis in gastrointestinal cancer cells via the CCK2 receptor

  2010cites this paper
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  2010cites this paper
• Gastrin: an acid-releasing, proliferative and immunomodulatory peptide?

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• The production and role of gastrin-17 and gastrin-17-gly in gastrointestinal cancers.

  2009cites this paper
• Gastrin induces the interaction between human mononuclear leukocytes and endothelial cells through the endothelial expression of P-selectin and VCAM-1.

  2009cites this paper
• G protein-coupled receptors stimulation and the control of cell migration.

  2009cites this paper
• CCK2 receptor expression transforms non‐tumorigenic human NCM356 colonic epithelial cells into tumor forming cells

  2009cites this paper
• Importance of gastrin in the pathogenesis and treatment of gastric tumors.

  2009cites this paper
• Gastrin activates paracrine networks leading to induction of PAI-2 via MAZ and ASC-1.

  2009cites this paper
• Flow cytometric detection of progastrin interaction with gastrointestinal cells.

  2008cites this paper
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  2007cites this paper
• Increased gastric expression of MMP-7 in hypergastrinemia and significance for epithelial-mesenchymal signaling.

  2007cites this paper
• G17DT: an antigastrin immunogen for the treatment of gastrointestinal malignancy

  2007cites this paper
• Attack and defence in the gastric epithelium – a delicate balance

  2007influential citation
• Lessons from the gastrin knockout mice.

  2007cites this paper
• Constitutively active CCK2 receptor splice variant increases Src-dependent HIF-1α expression and tumor growth

  2007cites this paper
• Effect of peroxisome proliferator‐activated receptor‐α agonist (bezafibrate) on gastric secretion and gastric cytoprotection in rats

  2007cites this paper
• CHAPTER 143 – Gastrin

  2006cites this paper
• Ectopeptidases in tumour biology: a review.

  2006cites this paper
• Cholecystokinin and gastrin receptors.

  2006cites this paper
• Attenuation of Peroxisome Proliferator-activated Receptor γ (PPARγ) Mediates Gastrin-stimulated Colorectal Cancer Cell Proliferation*

  2006cites this paper
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  2006cites this paper
• Attenuation of peroxisome proliferator-activated receptor gamma (PPARgamma) mediates gastrin-stimulated colorectal cancer cell proliferation.

  2006cites this paper
• Differentiation of the gastric mucosa. II. Role of gastrin in gastric epithelial cell proliferation and maturation.

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• Cholecystokinin-2 receptor modulates cell adhesion through β1-integrin in human pancreatic cancer cells

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• Inhibition of Epidermal Growth Factor Receptor Activation Enhances In Vivo Histamine-Stimulated Gastric Acid Secretion in the Rat

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• Role of CYP27A in cholesterol and bile acid metabolism Published, JLR Papers in Press, November 1, 2004. DOI 10.1194/jlr.M400219-JLR200

  2005cites this paper
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• Bi-directional Signaling between Gastrointestinal Peptide Hormone Receptors and Epidermal Growth Factor Receptor

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• Expression of cholecystokinin-2/gastrin receptor in the murine pancreas modulates cell adhesion and cell differentiation in vivo.

  2004cites this paper
• Gastrin: old hormone, new functions

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• Involvement of JAK2 upstream of the PI 3-kinase in cell-cell adhesion regulation by gastrin.

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• Role of progastrins and gastrins and their receptors in GI and pancreatic cancers: targets for treatment.

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• Helicobacter pylori Induces Plasminogen Activator Inhibitor 2 in Gastric Epithelial Cells through Nuclear Factor-κB and RhoA

  2004cites this paper
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  2003cites this paper
• EGFR signal transactivation in cancer cells.

  2003cites this paper