Diverse plant viruses: a toolbox for dissection of cellular pathways

Research in virology has usually focused on one selected host-virus pathosystem to examine the mechanisms underlying a particular disease. However, as exemplified by the mechanistically versatile suppression of antiviral RNA silencing by plant viruses, there may be functionally convergent evolution. Assuming this is a widespread feature, we propose that effector proteins from diverse plant viruses can be a powerful resource for discovering new regulatory mechanisms of distinct cellular pathways. The efficiency of this approach will depend on how deeply and widely the studied pathway is integrated into viral infections. Beyond this, comparative studies using broad virus diversity should increase our global understanding of plant-virus interactions.

• Publication year

  2019

• Venue

  Journal of Experimental Botany

• Publication date

  2019-03-18

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1093/jxb/erz122PMID 30882863PMCID 6598076
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Susceptibility Genes to Plant Viruses

  2018cited by this paper
• Barley stripe mosaic virus γb Protein Subverts Autophagy to Promote Viral Infection by Disrupting the ATG7-ATG8 Interaction

  2018cited by this paper
• Selective autophagy limits cauliflower mosaic virus infection by NBR1-mediated targeting of viral capsid protein and particles

  2017cited by this paper
• Arabidopsis thaliana as a model host for Brevipalpus mite-transmitted viruses

  2017cited by this paper
• Viral rewiring of cellular lipid metabolism to create membranous replication compartments

  2017cited by this paper
• Turnip Mosaic Virus Counteracts Selective Autophagy of the Viral Silencing Suppressor HCpro1

  2017cited by this paper
• The stress granule component G3BP is a novel interaction partner for the nuclear shuttle proteins of the nanovirus pea necrotic yellow dwarf virus and geminivirus abutilon mosaic virus.

  2017cited by this paper
• The roles of membranes and associated cytoskeleton in plant virus replication and cell-to-cell movement.

  2017cited by this paper
• Autophagy functions as an antiviral mechanism against geminiviruses in plants

  2017cited by this paper
• Nontargeted virus sequence discovery pipeline and virus clustering for metagenomic data

  2017cited by this paper
• Who Regulates Whom? An Overview of RNA Granules and Viral Infections

  2016cited by this paper
• NB-LRR signaling induces translational repression of viral transcripts and the formation of RNA processing bodies through mechanisms differing from those activated by UV stress and RNAi.

  2016cited by this paper
• The dual edge of RNA silencing suppressors in the virus-host interactions.

  2016cited by this paper
• Plant Virus Infection and the Ubiquitin Proteasome Machinery: Arms Race along the Endoplasmic Reticulum

  2016cited by this paper
• How does the stressed out ER find relief during virus infection?

  2016cited by this paper
• Elucidating the Role of Effectors in Plant-Fungal Interactions: Progress and Challenges

  2016cited by this paper
• The impact of phytohormones on virus infection and disease.

  2016cited by this paper
• Geminivirus Activates ASYMMETRIC LEAVES 2 to Accelerate Cytoplasmic DCP2-Mediated mRNA Turnover and Weakens RNA Silencing in Arabidopsis

  2015cited by this paper
• Plants, viruses and the environment: Ecology and mutualism.

  2015cited by this paper
• viral silencing suppressors: Tools forged to fine-tune host-pathogen coexistence.

  2015cited by this paper
• Different roles for RNA silencing and RNA processing components in virus recovery and virus-induced gene silencing in plants.

  2015cited by this paper
• NIK1-mediated translation suppression functions as a plant antiviral immunity mechanism

  2015cited by this paper
• Plasmodesmata: channels for viruses on the move.

  2015cited by this paper
• Viruses and cells intertwined since the dawn of evolution

  2015cited by this paper
• Evolution of viruses and cells: do we need a fourth domain of life to explain the origin of eukaryotes?

  2015cited by this paper
• Formation of Potato Virus A-Induced RNA Granules and Viral Translation Are Interrelated Processes Required for Optimal Virus Accumulation

  2015cited by this paper
• Water Balance, Hormone Homeostasis, and Sugar Signaling Are All Involved in Tomato Resistance to Tomato Yellow Leaf Curl Virus1[C][W][OPEN]

  2014cited by this paper
• Viral Manipulation of Plant Host Membranes.

  2014cited by this paper
• Cloning of the Arabidopsis rwm1 gene for resistance to Watermelon mosaic virus points to a new function for natural virus resistance genes.

  2014cited by this paper
• Cell-to-cell movement of viruses via plasmodesmata

  2014cited by this paper
• Plant Immune Responses Against Viruses: How Does a Virus Cause Disease?[OA]

  2013cited by this paper
• Autophagy and Viruses: Adversaries or Allies?

  2013cited by this paper
• Assessing Global Transcriptome Changes in Response to South African Cassava Mosaic Virus [ZA-99] Infection in Susceptible Arabidopsis thaliana

  2013cited by this paper
• FIRST REPORT OF COCHLIOBOLUS AUSTRALIENSIS CAUSING LEAF SPOT OF BERMUDAGRASS IN PAKISTAN

  2013cited by this paper
• Citrus leprosis virus C infects Arabidopsis thaliana, the model for plant-pathogen interactions

  2013influential reference
• Exploitation of natural genetic diversity to study plant-virus interactions: what can we learn from Arabidopsis thaliana?

  2013cited by this paper
• The absence of eukaryotic initiation factor eIF(iso)4E affects the systemic spread of a Tobacco etch virus isolate in Arabidopsis thaliana.

  2013cited by this paper
• Human viruses: discovery and emergence

  2012cited by this paper
• Lectin-Mediated Resistance Impairs Plant Virus Infection at the Cellular Level[C][W][OA]

  2012cited by this paper
• Viral population dynamics and virulence thresholds.

  2012cited by this paper
• Do persistent RNA viruses fit the trade-off hypothesis of virulence evolution?

  2012cited by this paper
• Susceptibility of Arabidopsis Ecotypes to Infection by Iris yellow spot virus

  2012cited by this paper
• Advances in plant virus evolution: translating evolutionary insights into better disease management.

  2011cited by this paper
• Processing bodies and plant development.

  2011cited by this paper
• Natural Variation in Arabidopsis: From Molecular Genetics to Ecological Genomics1[W][OA]

  2011cited by this paper
• ARGONAUTE2 Mediates RNA-Silencing Antiviral Defenses against Potato virus X in Arabidopsis1[W][OA]

  2011cited by this paper
• Top 10 plant viruses in molecular plant pathology.

  2011cited by this paper
• Emerging viral diseases of tomato crops.

  2010cited by this paper
• Arabidopsis thaliana as a model for the study of plant–virus co-evolution

  2010cited by this paper
• The virulence–transmission trade-off in vector-borne plant viruses: a review of (non-)existing studies

  2010cited by this paper
• The first DNA 1-like alpha satellites in association with New World begomoviruses in natural infections.

  2010cited by this paper
• Horizontal gene transfer: sustaining pathogenicity and optimizing host-pathogen interactions.

  2009cited by this paper
• A model system for plant-virus interaction—infectivity and seed transmission of Cherry leaf roll virus (CLRV) in Arabidopsis thaliana

  2009cited by this paper
• Apple latent spherical virus vectors for reliable and effective virus-induced gene silencing among a broad range of plants including tobacco, tomato, Arabidopsis thaliana, cucurbits, and legumes.

  2009cited by this paper
• Rates of evolutionary change in viruses: patterns and determinants

  2008cited by this paper
• Agroinfection of cloned Sri Lankan cassava mosaic virus DNA to Arabidopsis thaliana, Nicotiana tabacum and cassava

  2008cited by this paper
• Structural and Genetic Requirements for the Biogenesis of Tobacco Rattle Virus-Derived Small Interfering RNAs

  2008cited by this paper
• Transcriptional analysis of complementary sense genes in Spinach curly top virus and functional role of C2 in pathogenesis.

  2007cited by this paper
• Interactions between Brome Mosaic Virus RNAs and Cytoplasmic Processing Bodies

  2007cited by this paper
• Arabidopsis thaliana is a host of the legume nanovirus Faba bean necrotic yellows virus.

  2007cited by this paper
• Identification and Host Relations of Turnip ringspot virus, A Novel Comovirus from Ohio.

  2007cited by this paper
• The complete genomes of three viruses assembled from shotgun libraries of marine RNA virus communities

  2007cited by this paper
• The Polerovirus F box protein P0 targets ARGONAUTE1 to suppress RNA silencing.

  2007cited by this paper
• Arabidopsis thaliana is an asymptomatic host of Alfalfa mosaic virus.

  2006cited by this paper
• Multiple resistance traits control Plum pox virus infection in Arabidopsis thaliana.

  2006cited by this paper
• Beet poleroviruses: close friends or distant relatives?

  2005cited by this paper
• Synthesis of infectious in vitro transcripts from Cassia yellow blotch bromovirus cDNA clones and a reassortment analysis with other bromoviruses in protoplasts

  2005cited by this paper
• Symbiosis versus competition in plant virus evolution

  2005cited by this paper
• A Sobemovirus coat protein gene complements long-distance movement of a coat protein-null Dianthovirus.

  2004cited by this paper
• Infection and RNA recombination of Brome mosaic virus in Arabidopsis thaliana.

  2004cited by this paper
• Nucleotide sequence of Chinese rape mosaic virus (oilseed rape mosaic virus), a crucifer tobamovirus infectious on Arabidopsis thaliana

  2004cited by this paper
• Multiple resistance phenotypes to Lettuce mosaic virus among Arabidopsis thaliana accessions.

  2003cited by this paper
• Complete nucleotide sequence of spring beauty latent virus, a bromovirus infectious to Arabidopsis thaliana

  2003cited by this paper
• Mutations that delay flowering in Arabidopsis de-couple symptom response from cauliflower mosaic virus accumulation during infection.

  2002cited by this paper
• Asymmetric infectivity of pseudorecombinants of cabbage leaf curl virus and squash leaf curl virus: implications for bipartite geminivirus evolution and movement.

  1998cited by this paper
• Pathogenic interactions between variants of cauliflower mosaic virus and Arabidopsis thaliana

  1998cited by this paper
• Identification of three genetic loci controlling leaf senescence in Arabidopsis thaliana.

  1997cited by this paper
• Identification of three genetic loci controlling leaf senescence in Arabidopsis thaliana

  1997cited by this paper
• Movement and subcellular localization of a tobamovirus in Arabidopsis.

  1997cited by this paper
• Identification and map location of TTR1, a single locus in Arabidopsis thaliana that confers tolerance to tobacco ringspot nepovirus.

  1996cited by this paper
• Infection ofArabidopsis thaliana ecotype columbia by tomato spotted wilt virus

  1995cited by this paper
• Suitability of Arabidopsis thaliana as a system for the study of plant-virus interactions.

  1994cited by this paper
• Hypersensitive response in cucumber mosaic virus-inoculated Arabidopsis thaliana

  1994cited by this paper
• Identification of loci in Arabidopsis that confer resistance to geminivirus infection.

  1994cited by this paper
• The genomic sequence of cardamine chlorotic fleck carmovirus.

  1993cited by this paper
• Isolation of mutants of Arabidopsis thaliana in which accumulation of tobacco mosaic virus coat protein is reduced to low levels

  1991cited by this paper
• Symptom intensification on cruciferous hosts by the virulent satellite RNA of turnip crinkle virus.

  1990cited by this paper
• Symptoms of Cauliflower Mosaic Virus Infection in Arabidopsis thaliana and Turnip

  1989cited by this paper

• A novel RAV transcription factor from pear interacts with viral RNA-silencing suppressors to inhibit viral infection.

  2024cites this paper
• Urdbean Leaf Crinkle Virus: A Mystery Waiting to Be Solved

  2023cites this paper
• Assembly of plant virus agroinfectious clones using biological material or DNA synthesis

  2022cites this paper
• Transcriptional Regulatory Networks Associate with Early Stages of Potato Virus X Infection of Solanum tuberosum

  2021cites this paper
• Turnip crinkle virus targets host ATG8 proteins to attenuate antiviral autophagy

  2021cites this paper
• G3BPs in Plant Stress

  2021cites this paper