The myeloid-cell-specific c-fes promoter is regulated by Sp1, PU.1, and a novel transcription factor

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Molecular and Cellular Biology

• Publication date

  1996-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.16.4.1676PMID 8657143PMCID PMC231154
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• DNA binding specificities of Spi-1/PU.1 and Spi-B transcription factors and identification of a Spi-1/Spi-B binding site in the c-fes/c-fps promoter.

  1995cited by this paper
• Activation of the granulocyte-macrophage colony-stimulating factor promoter in T cells requires cooperative binding of Elf-1 and AP-1 transcription factors

  1994cited by this paper
• The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells

  1994cited by this paper
• The Fps/Fes protein-tyrosine kinase promotes angiogenesis in transgenic mice

  1994cited by this paper
• c-fes expression in ontogenetic development and hematopoietic differentiation.

  1994cited by this paper
• Combinatorial interactions between AP-1 and ets domain proteins contribute to the developmental regulation of the macrophage scavenger receptor gene

  1994cited by this paper
• Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages.

  1994cited by this paper
• The macrophage transcription factor PU.1 directs tissue-specific expression of the macrophage colony-stimulating factor receptor

  1993cited by this paper
• c‐fps/fes protein‐tyrosine kinase is implicated in a signaling pathway triggered by granulocyte‐macrophage colony‐stimulating factor and interleukin‐3.

  1993cited by this paper
• Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation

  1993cited by this paper
• Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell types.

  1993cited by this paper
• Molecular regulation of the human IL-3 gene: inducible T cell- restricted expression requires intact AP-1 and Elf-1 nuclear protein binding sites

  1993cited by this paper
• The proto-oncogene PU.1 regulates expression of the myeloid-specific CD11b promoter.

  1993influential reference
• The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB.

  1993cited by this paper
• PU.1Recruits a SecondNuclear Factor toa Site Important for Immunoglobulin K 3'Enhancer Activity

  1992cited by this paper
• Expression of truncated transcripts of the proto-oncogene c-fps/fes in human lymphoma and lymphoid leukemia cell lines.

  1992cited by this paper
• Evolutionarily conserved Ets family members display distinct DNA binding specificities [published erratum appears in J Exp Med 1993 Sep 1;178(3):1133]

  1992cited by this paper
• Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element.

  1992cited by this paper
• PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity

  1992cited by this paper
• A novel modulator domain of Ets transcription factors.

  1992cited by this paper
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  1991cited by this paper
• A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells.

  1991cited by this paper
• Optimization of transient transfection into human myeloid cell lines using a luciferase reporter gene.

  1991cited by this paper
• Differential effects of c-myb and c-fes antisense oligodeoxynucleotides on granulocytic differentiation of human myeloid leukemia HL60 cells.

  1990cited by this paper
• Characterization of human and mouse c-fes cDNA clones and identification of the 5' end of the gene.

  1990cited by this paper
• The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene.

  1990cited by this paper
• Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor.

  1990cited by this paper
• Myeloid expression of the human c-fps/fes proto-oncogene in transgenic mice

  1990cited by this paper
• Expression pattern of c‐fes oncogene mRNA in human myeloid cells

  1989cited by this paper
• K562 leukemia cells transfected with the human c-fes gene acquire the ability to undergo myeloid differentiation.

  1989influential reference
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  1988cited by this paper
• Identification of the differentiation-associated p93 tyrosine protein kinase of HL-60 leukemia cells as the product of the human c-fes locus and its expression in myelomonocytic cells.

  1988cited by this paper
• The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck.

  1988cited by this paper
• Association of p93c-fes tyrosine protein kinase with granulocytic/monocytic differentiation and resistance to differentiating agents in HL-60 leukemia cells.

  1988cited by this paper
• Evolutionary conserved close linkage of the c‐fes/fps proto‐oncogene and genetic sequences encoding a receptor‐like protein.

  1986cited by this paper
• The structure of the human c‐fes/fps proto‐oncogene.

  1985cited by this paper
• Preferential expression of the c-fps protein in chicken macrophages and granulocytic cells

  1985cited by this paper
• Expression of the mammalian c-fes protein in hematopoietic cells and identification of a distinct fes-related protein

  1985cited by this paper
• Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells.

  1985cited by this paper
• The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter.

  1983cited by this paper
• Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.

  1983cited by this paper
• A Multipotential Leukemia Cell Line (K-562) of Human Origin 1

  1981cited by this paper

• Elf1 Deficiency Impairs Macrophage Development in Zebrafish Model Organism

  2025cites this paper
• The FES Gene at the 15q26 Coronary-Artery-Disease Locus Inhibits Atherosclerosis

  2022cites this paper
• A frameshift variant in specificity protein 1 triggers superactivation of Sp1-mediated transcription in familial bone marrow failure

  2020cites this paper
• Kinases/Phosphatases | Fes Tyrosine Kinase

  2020cites this paper
• MicroRNA-125b inhibits AML cells differentiation by directly targeting Fes.

  2017cites this paper
• E2A Antagonizes PU.1 Activity through Inhibition of DNA Binding

  2016cites this paper
• Prostacyclin receptors: Transcriptional regulation and novel signalling mechanisms.

  2015cites this paper
• Autoregulation of c-Fes by intramolecular interaction of the F-BAR and SH2 domains: a novel role for the unique N-terminal region

  2013cites this paper
• transgenic mice A minimal c-fes cassette directs myeloid-specific expression in

  2013cites this paper
• FES/FER kinase signaling in hematopoietic cells and leukemias.

  2012cites this paper
• The role of transcription factors PU.1 and GATA-1 during leukemia differentiation

  2011cites this paper
• Biochemical correction of X-CGD by a novel chimeric promoter regulating high levels of transgene expression in myeloid cells.

  2011cites this paper
• Comprehensive gene expression microarray analysis of Ets-1 blockade in PC3 prostate cancer cells and correlations with prostate cancer tissues: Insights into genes involved in the metastatic cascade.

  2011cites this paper
• The role of PU.1 and GATA-1 transcription factors during normal and leukemogenic hematopoiesis

  2010cites this paper
• Promoter methylation blocks FES protein‐tyrosine kinase gene expression in colorectal cancer

  2009cites this paper
• Transcriptional regulation of the human prostacyclin receptor gene is dependent on Sp1, PU.1 and Oct-1 in megakaryocytes and endothelial cells.

  2009cites this paper
• Reduced PU.1 concentrations lead to hematopoietic stem cell defects and lineage-inappropriate gene expression.

  2009cites this paper
• Characterizing the function of the Fps/Fes tyrosine kinase in the mammary gland

  2008cites this paper
• Investigating the regulation of c-Fes non-receptor tyrosine kinase activation and gene expression

  2008influential citation
• The Transcriptional Repressor GFI-1 Antagonizes PU.1 Activity through Protein-Protein Interaction*

  2007cites this paper
• Transcriptional regulation of c-fms gene expression

  2007cites this paper
• Granulocyte colony-stimulating factor-induced upregulation of Jak3 transcription during granulocytic differentiation is mediated by the cooperative action of Sp1 and Stat3

  2006cites this paper
• PU.1 phosphorylation correlates with hydroquinone-induced alterations in myeloid differentiation and cytokine-dependent clonogenic response in human CD34+ hematopoietic progenitor cells

  2006cites this paper
• PU.1 Regulates Cathepsin S Expression in Professional APCs1

  2006cites this paper
• Characterization of a novel, cytokine-inducible carboxypeptidase D isoform in haematopoietic tumour cells.

  2005cites this paper
• Activation of the Jak3 pathway and myeloid differentiation

  2005cites this paper
• PU.1 Regulates Cathepsin S Expression in

  2005cites this paper
• Mechanisms associated with IL-6-induced up-regulation of Jak3 and its role in monocytic differentiation.

  2004cites this paper
• Tissue-specific targeting for cardiovascular gene transfer. Potential vectors and future challenges.

  2004cites this paper
• Sp1 control of gene expression in myeloid cells.

  2004cites this paper
• The Fes tyrosine kinase: a signal transducer that regulates myeloid-specific gene expression through transcriptional activation.

  2004cites this paper
• Transcriptional Regulation of CHI3L1, a Marker Gene for Late Stages of Macrophage Differentiation*

  2003cites this paper
• Identification of the human HEX1/hExo1 gene promoter and characterization of elements responsible for promoter activity.

  2003cites this paper
• Pub, a novel PU.1 binding protein, regulates the transcriptional activity of PU.1.

  2003cites this paper
• GA-binding protein (GABP) and Sp1 are required, along with retinoid receptors, to mediate retinoic acid responsiveness of CD18 (beta 2 leukocyte integrin): a novel mechanism of transcriptional regulation in myeloid cells.

  2003cites this paper
• Identification and characterization of a PU.1/Spi-B binding site in the bovine leukemia virus long terminal repeat

  2003cites this paper
• Interferon-Gamma-Activated Gene Expression

  2003cites this paper
• Closing in on the biological functions of fps/fes and fer

  2002cites this paper
• Activated Fes Protein Tyrosine Kinase Induces Terminal Macrophage Differentiation of Myeloid Progenitors (U937 Cells) and Activation of the Transcription Factor PU.1

  2002cites this paper
• Macrophage-Specific Gene Expression: Current Paradigms and Future Challenges

  2002cites this paper
• Structural characterization of the human carboxypeptidase D gene and its promoter.

  2002cites this paper
• A Novel Role of Sp1 and Sp3 in the Interferon-γ-mediated Suppression of Macrophage Lipoprotein Lipase Gene Transcription*

  2002cites this paper
• Transcriptional mechanisms regulating myeloid-specific genes.

  2002cites this paper
• Characterization of the 5'-flanking region of the human PTK6 gene.

  2002cites this paper
• Transcriptional regulation of granulocyte and monocyte development

  2002cites this paper
• Structure of the human carboxypeptidase M gene. Identification of a proximal GC-rich promoter and a unique distal promoter that consists of repetitive elements.

  2002cites this paper
• Transcription Factors that Regulate Growth and Differentiation of Myeloid Cells

  2001cites this paper
• Transcriptional regulation of hemopoiesis.

  2001cites this paper
• Transcriptional regulation of c-fms gene expression.

  2001cites this paper
• AKT Induces Transcriptional Activity of PU.1 through Phosphorylation-mediated Modifications within Its Transactivation Domain*

  2001cites this paper
• Differential Cooperation between Regulatory Sequences Required for Human CD53 Gene Expression*

  2001cites this paper
• Fes-Cre Targets Phosphatidylinositol Glycan Class a (Piga) Inactivation to Hematopoietic Stem Cells in the Bone Marrow

  2001cites this paper
• Sp1 and C/EBP are necessary to activate the lactoferrin gene promoter during myeloid differentiation.

  2000cites this paper
• Ets target genes: past, present and future

  2000cites this paper
• PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene*

  2000cites this paper
• Regulation of granulopoiesis by transcription factors and cytokine signals

  2000cites this paper
• A minimal c-fescassette directs myeloid-specific expression in transgenic mice

  2000cites this paper
• A minimal c-fes cassette directs myeloid-specific expression in transgenic mice.

  2000cites this paper
• TFEC is a macrophage-restricted member of the microphthalmia-TFE subfamily of basic helix-loop-helix leucine zipper transcription factors.

  1999cites this paper
• PU.1 and USF Are Required for Macrophage-specific Mannose Receptor Promoter Activity*

  1999cites this paper
• Tyrosine kinases in neutrophils.

  1999cites this paper
• An Enhancer Located between the Neutrophil Elastase and Proteinase 3 Promoters Is Activated by Sp1 and an Ets Factor*

  1999cites this paper
• Prf, a novel Ets family protein that binds to the PU.1 binding motif, is specifically expressed in restricted stages of B cell development.

  1999cites this paper
• Elf-1 and PU.1 induce expression of gp91(phox) via a promoter element mutated in a subset of chronic granulomatous disease patients.

  1999cites this paper
• The Ets Factors PU.1 and Spi-B Regulate the Transcriptionin Vivo of P2Y10, a Lymphoid Restricted Heptahelical Receptor*

  1999cites this paper
• The key role of PU.1/SPI-1 in B cells, myeloid cells and macrophages.

  1999cites this paper
• SPI-B Activates Transcription via a Unique Proline, Serine, and Threonine Domain and Exhibits DNA Binding Affinity Differences from PU.1*

  1999cites this paper
• Identification and functional characterization of the murine Rac2 gene promoter.

  1999cites this paper
• Transcription Factors Helix-Loop-Helix Leucine Zipper the Microphthalmia-TFE Subfamily of Basic TFEC Is a Macrophage-Restricted Member of

  1999cites this paper
• The c-Fes family of protein-tyrosine kinases.

  1998cites this paper
• Myeloid‐specific gene expression

  1998cites this paper
• PU.1/Spi-1 is essential for the B cell-specific activity of the mouse CD72 promoter.

  1998cites this paper
• The Transcription Factor Sp1 Regulates the Myeloid-specific Expression of the Human Hematopoietic Cell Kinase (HCK) Gene through Binding to Two Adjacent GC Boxes within the HCK Promoter-Proximal Region*

  1998cites this paper
• Mouse CD 72 Promoter PU . 1 / Spi-1 Is Essential for the B Cell-Specific

  1998cites this paper
• PU.1 and hematopoiesis: lessons learned from gene targeting experiments.

  1998cites this paper
• Isolation and characterization of a chicken homologue of the Spi-1/PU.1 transcription factor

  1998cites this paper
• Role of PU.1 in Hematopoiesis

  1998cites this paper
• Expression Pattern of the Ets-related Transcription Factor Elf-1

  1998cites this paper
• Sp1 Cooperates with the ets Transcription Factor, GABP, to Activate the CD18 (β2 Leukocyte Integrin) Promoter*

  1998cites this paper
• Interaction between PU.1 and Another Ets Family Transcription Factor Promotes Macrophage-specific Basal Transcription Initiation*

  1998cites this paper
• Expression systems

  1997cites this paper
• Activation of the Megakaryocyte-specific Gene Platelet Basic Protein (PBP) by the Ets Family Factor PU.1*

  1997cites this paper
• Transcription factors, normal myeloid development, and leukemia.

  1997cites this paper
• The role of Ets transcription factors in the development and function of the mammalian immune system.

  1997cites this paper
• Expression of Two Myeloid Cell-specific Genes Requires the Novel Transcription Factor, c-fes Expression Factor*

  1997cites this paper
• Defective B cell receptor‐mediated responses in mice lacking the Ets protein, Spi‐B

  1997cites this paper
• Characterization of the bovine prion protein gene: the expression requires interaction between the promoter and intron.

  1997cites this paper
• Physical interactions between Ets and NF-kappaB/NFAT proteins play an important role in their cooperative activation of the human immunodeficiency virus enhancer in T cells

  1997cites this paper
• Structural and functional analyses of DNA bending induced by Sp1 family transcription factors.

  1997cites this paper
• The Ets protein Spi-B is expressed exclusively in B cells and T cells during development

  1996cites this paper